2018
Mapping the Proteome of the Synaptic Cleft through Proximity Labeling Reveals New Cleft Proteins
Cijsouw T, Ramsey AM, Lam TT, Carbone BE, Blanpied TA, Biederer T. Mapping the Proteome of the Synaptic Cleft through Proximity Labeling Reveals New Cleft Proteins. Proteomes 2018, 6: 48. PMID: 30487426, PMCID: PMC6313906, DOI: 10.3390/proteomes6040048.Peer-Reviewed Original ResearchProximity labelingLabel-free quantitation mass spectrometryReceptor-type tyrosine-protein phosphatase zetaProximity labeling approachCell-cell contactSynaptic cleftPost-synaptic specializationsProteomic contentSynapse heterogeneitySynCAM 1Confocal microcopySurface proteinsCell surfaceProteomeSuper-resolution imagingCultured cortical neuronsMammalian brainLabeling approachMolecular compositionReporterProteinCortical neuronsFunctional organizationExcitatory synapsesDiverse set
2015
Key Molecules: SynCAM Proteins☆
Biederer T, Shrestha N. Key Molecules: SynCAM Proteins☆. 2015 DOI: 10.1016/b978-0-12-801238-3.04784-x.Peer-Reviewed Original ResearchSynaptic cell adhesion moleculesPostsynaptic neurotransmitter receptorsPresynaptic release machineryCell adhesion moleculeAdhesion proteinsPost-synaptic specializationsInstructive signalsContact sitesSynaptic contact sitesRelease machinerySynapse inductionCentral nervous systemAdhesion moleculesNeurotransmitter receptorsProteinSynaptic specializationsNervous systemAsymmetric sitesSpecializationMachinerySitesConcomitant formationAssemblyInductionFamily