Angiotensin-Converting Enzyme in the Male Rat Reproductive System: Autoradiographic Visualization with [3H]Captopril*
STRITTMATTER S, SNYDER S. Angiotensin-Converting Enzyme in the Male Rat Reproductive System: Autoradiographic Visualization with [3H]Captopril*. Endocrinology 1984, 115: 2332-2341. PMID: 6094156, DOI: 10.1210/endo-115-6-2332.Peer-Reviewed Original ResearchConceptsACE activityMale rat reproductive systemRat reproductive systemSoluble ACE activityAutoradiographic silver grainsStages I-VIIIInitial segmentMale ratsAutoradiographic visualizationPharmacological profileTesticular slicesBasal epitheliumSilver grainsLuminal labellingReproductive tractInterstitial tissueMonoclonal antibodiesVas deferensSeminiferous tubulesLevel of bindingReproductive systemLuminal surfaceEpitheliumA fluorometric assay for angiotensin-converting enzyme activity
Kapiloff M, Strittmatter S, Fricker L, Snyder S. A fluorometric assay for angiotensin-converting enzyme activity. Analytical Biochemistry 1984, 140: 293-302. PMID: 6091493, DOI: 10.1016/0003-2697(84)90167-2.Peer-Reviewed Original ResearchAutoradiographic visualization of angiotensin-converting enzyme in rat brain with [3H]captopril: localization to a striatonigral pathway.
Strittmatter SM, Lo MM, Javitch JA, Snyder SH. Autoradiographic visualization of angiotensin-converting enzyme in rat brain with [3H]captopril: localization to a striatonigral pathway. Proceedings Of The National Academy Of Sciences Of The United States Of America 1984, 81: 1599-1603. PMID: 6324207, PMCID: PMC344885, DOI: 10.1073/pnas.81.5.1599.Peer-Reviewed Original ResearchConceptsCaudate putamenSubstantia nigraStriatonigral pathwayRat brainAngiotensin II involvementIpsilateral caudate putamenTrans-synaptic changesIpsilateral substantia nigraMedian preoptic areaAngiotensin-converting enzymeLack of effectStriatal interneuronsAngiotensin IIEntopeduncular nucleusNeuronal perikaryaSubfornical organZona reticulataGlobus pallidusACE activityLocus coeruleusParaventricular nucleusPreoptic areaIbotenic acidMedial habenulaNeuronal pathways