2020
Continuation phase treatment outcomes for switching, combining, or augmenting strategies for treatment‐resistant major depressive disorder: A VAST‐D report
Zisook S, Johnson G, Hicks P, Chen P, Beresford T, Michalets J, Rao S, Thase M, Wilcox J, Sevilimedu V, Mohamed S. Continuation phase treatment outcomes for switching, combining, or augmenting strategies for treatment‐resistant major depressive disorder: A VAST‐D report. Depression And Anxiety 2020, 38: 185-195. PMID: 33225492, DOI: 10.1002/da.23114.Peer-Reviewed Original ResearchMeSH KeywordsAntidepressive AgentsDepressive Disorder, MajorDepressive Disorder, Treatment-ResistantHumansQuality of LifeTreatment OutcomeConceptsDepressive symptom severityContinuation treatmentBupropion SRTreatment outcomesTreatment-resistant major depressive disorderSymptom severitySignificant differential treatment effectsContinuation treatment phaseAcute-phase treatmentAbnormal laboratory valuesLower relapse rateMajor depressive disorderQuality of lifeLess anxietyDifferential treatment effectsMore somnolenceDry mouthRelapse rateExtrapyramidal effectsFull remissionWeek 12Continuation phaseTreatment attemptsDepressive disorderLaboratory values
2016
Comparison of Intensive Case Management for Psychotic and Nonpsychotic Patients
Mohamed S. Comparison of Intensive Case Management for Psychotic and Nonpsychotic Patients. Psychological Services 2016, 13: 10-19. PMID: 26168139, DOI: 10.1037/ser0000041.Peer-Reviewed Original ResearchConceptsAssertive community treatmentPsychotic symptomsAnalysis of covariancePsychotic disordersIntensive case management programIntensive case management servicesSevere psychotic symptomsIntensive case managementCommunity-based careCase management programCase management servicesInpatient bed availabilityCommunity-based service programsBaseline characteristicsMedication complianceNonpsychotic patientsNonpsychotic disordersOutcome dataPsychotic diagnosesHospital useCommunity treatmentSuch symptomsBed availabilitySymptomsCase management
2014
Insight and attitudes towards medication among inpatients with chronic schizophrenia in the US and China
Mohamed S, Rosenheck R, He H, Yuping N. Insight and attitudes towards medication among inpatients with chronic schizophrenia in the US and China. Social Psychiatry And Psychiatric Epidemiology 2014, 49: 1063-1070. PMID: 24549835, DOI: 10.1007/s00127-014-0824-1.Peer-Reviewed Original ResearchConceptsDrug Attitude InventorySchizophrenia symptomsPsychiatric hospitalOverall severityMeasures of insightGuangzhou Psychiatric HospitalTime of admissionBenefits of medicationsLarge psychiatric hospitalNegative Syndrome ScaleTreatment Attitudes QuestionnaireSymptoms of schizophreniaAcceptance of medicationHospitalized patientsAntipsychotic treatmentDAI scoresChronic schizophreniaMedicationsAnalysis of covarianceSyndrome ScaleMental illnessBivariate analysisSymptomsLarger studySchizophrenia
2010
Impact of second-generation antipsychotics and perphenazine on depressive symptoms in a randomized trial of treatment for chronic schizophrenia.
Addington DE, Mohamed S, Rosenheck RA, Davis SM, Stroup TS, McEvoy JP, Swartz MS, Lieberman JA. Impact of second-generation antipsychotics and perphenazine on depressive symptoms in a randomized trial of treatment for chronic schizophrenia. The Journal Of Clinical Psychiatry 2010, 72: 75-80. PMID: 20868641, PMCID: PMC5052810, DOI: 10.4088/jcp.09m05258gre.Peer-Reviewed Original ResearchConceptsMajor depressive episodeSecond-generation antipsychoticsDSM-IV-defined schizophreniaCurrent major depressive episodeClinical practice recommendationsTrial of treatmentClinical practice guidelinesTreatment of depressionCalgary Depression ScaleClinical Antipsychotic TrialsSecond-generation drugsSymptoms of depressionPhase 1 analysisTardive dyskinesiaDepressive episodeChronic schizophreniaAntipsychotic TrialsPractice guidelinesDepression ScaleDepressive symptomsTreatment groupsBaseline scoresPatientsAntipsychoticsPractice recommendations
2009
Veterans Affairs Intensive Case Management for Older Veterans
Mohamed S, Neale MS, Rosenheck R. Veterans Affairs Intensive Case Management for Older Veterans. American Journal Of Geriatric Psychiatry 2009, 17: 671-681. PMID: 19625784, DOI: 10.1097/jgp.0b013e3181a88340.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge DistributionAgedAged, 80 and overCase ManagementCommunity Mental Health ServicesEvidence-Based PracticeFemaleHealth Services AccessibilityHumansLength of StayMaleMental DisordersMiddle AgedPsychiatric Status Rating ScalesSurveys and QuestionnairesTreatment OutcomeUnited StatesUnited States Department of Veterans AffairsVeteransConceptsSevere mental illnessAssertive community treatmentOlder veteransIntensive case management programComorbid substance abuseNursing home placementIntensive case managementLate-onset problemsCase management programCommunity-based servicesRecovery-oriented servicesNonpsychotic illnessesYounger patientsEvidence-based practiceHospital treatmentElderly veteransTreatment outcomesFamily burdenCommunity treatmentRespite servicesMental illnessRecovery-focused servicesCase managementSubstance abuseElderly people
2008
Cross-sectional and Longitudinal Relationships Between Insight and Attitudes Toward Medication and Clinical Outcomes in Chronic Schizophrenia
Mohamed S, Rosenheck R, McEvoy J, Swartz M, Stroup S, Lieberman JA. Cross-sectional and Longitudinal Relationships Between Insight and Attitudes Toward Medication and Clinical Outcomes in Chronic Schizophrenia. Schizophrenia Bulletin 2008, 35: 336-346. PMID: 18586692, PMCID: PMC2659303, DOI: 10.1093/schbul/sbn067.Peer-Reviewed Original ResearchConceptsPositive medication attitudesMedication attitudesSymptoms of schizophreniaSchizophrenia symptomsGreater medication complianceDrug Attitude InventoryRelationship of insightClinical Antipsychotic TrialsTreatment Attitudes QuestionnaireGreater patient understandingLevel of depressionMixed model regression analysisLower symptom levelsRecovery-oriented servicesClinical outcomesMedication adherenceMedication complianceChronic schizophreniaAntipsychotic TrialsPatient understandingModel regression analysisMedicationsCommunity functioningPsychosocial rehabilitationSymptoms
2007
Subsyndromal Depressive Symptoms in Middle-Aged and Older Persons with Schizophrenia
Zisook S, Montross L, Kasckow J, Mohamed S, Palmer BW, Patterson TL, Golshan S, Fellows I, Lehman D, Solorzano E. Subsyndromal Depressive Symptoms in Middle-Aged and Older Persons with Schizophrenia. American Journal Of Geriatric Psychiatry 2007, 15: 1005-1014. PMID: 18056819, DOI: 10.1097/jgp.0b013e3180a725ec.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsChronic DiseaseCitalopramComorbidityDepressionDepressive Disorder, MajorDouble-Blind MethodFemaleFollow-Up StudiesHealth StatusHumansMaleMiddle AgedPlacebosPsychiatric Status Rating ScalesPsychotic DisordersSchizophreniaSchizophrenic PsychologySelective Serotonin Reuptake InhibitorsSuicideTreatment OutcomeConceptsSubsyndromal depressive symptomsDepressive symptomsOlder patientsClinical featuresSchizoaffective disorderNegative symptomsHamilton Depression Rating ScaleImportant clinical dimensionGeneral medical conditionsDepression Rating ScaleSpecific depressive symptomsMental functioningSubstantial morbiditySevere akathisiaMovement abnormalitiesChronic schizophreniaMedical conditionsDepression groupOverall psychopathologyIntervention studiesDepressive symptomatologyPatientsSymptomsOlder personsGeneral psychopathology
2006
Discriminating Between Cognitive and Supportive Group Therapies for Chronic Mental Illness
Hayes SA, Hope DA, Terryberry-Spohr LS, Spaulding WD, VanDyke M, Elting DT, Poland J, Mohamed S, Garbin CP, Reed D, Sullivan M. Discriminating Between Cognitive and Supportive Group Therapies for Chronic Mental Illness. The Journal Of Nervous And Mental Disease 2006, 194: 603-609. PMID: 16909069, DOI: 10.1097/01.nmd.0000230635.03400.2d.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttitude of Health PersonnelAttitude to HealthChronic DiseaseCognitive Behavioral TherapyCohort StudiesFemaleHospitalizationHumansMaleMental DisordersPhysician-Patient RelationsPsychotherapeutic ProcessesPsychotherapy, GroupQ-SortReproducibility of ResultsTape RecordingTreatment OutcomeConceptsChronic mental illnessSupportive group therapyMental illnessGroup therapyPharmacological treatmentQ-sort processTherapyLarger studyIllnessTherapists' attitudesCognitive groupTherapy skillsTreatmentCognitive therapySupportive groupGroupSpecific factorsInpatientsParticipants' attitudesCommon factors