2018
Intraosseous versus intravenous access in patients with out-of-hospital cardiac arrest: Insights from the resuscitation outcomes consortium continuous chest compression trial
Mody P, Brown SP, Kudenchuk PJ, Chan PS, Khera R, Ayers C, Pandey A, Kern K, de Lemos JA, Link MS, Idris AH. Intraosseous versus intravenous access in patients with out-of-hospital cardiac arrest: Insights from the resuscitation outcomes consortium continuous chest compression trial. Resuscitation 2018, 134: 69-75. PMID: 30391366, DOI: 10.1016/j.resuscitation.2018.10.031.Peer-Reviewed Original ResearchConceptsFavorable neurological functionIntravenous accessNeurological functionIntraosseous accessCompression trialHospital cardiac arrest resuscitationInitial drug administrationHospital cardiac arrestCardiac arrest resuscitationOptimal access routeDelivery of medicationsBystander cardiopulmonary resuscitationRate of survivalSustained ROSCHospital survivalInitial rhythmHospital dischargeOHCA patientsROSC rateSpontaneous circulationUnadjusted outcomesSustained returnCardiac arrestCardiopulmonary resuscitationPatients
2016
Hospital Variation in Time to Epinephrine for Nonshockable In-Hospital Cardiac Arrest
Khera R, Chan PS, Donnino M, Girotra S. Hospital Variation in Time to Epinephrine for Nonshockable In-Hospital Cardiac Arrest. Circulation 2016, 134: 2105-2114. PMID: 27908910, PMCID: PMC5173427, DOI: 10.1161/circulationaha.116.025459.Peer-Reviewed Original ResearchConceptsHospital cardiac arrestEpinephrine administrationCardiac arrestFunctional recoveryHospital variationNonshockable rhythmsHospital ratesSurvival rateRisk-standardized survival ratesIn-Hospital Cardiac ArrestHospital-level outcomesRisk-standardized ratesDose of epinephrineMedian survival rateOdds of delayHigh rateGuidelines-ResuscitationAdult patientsOverall survivalWorse survivalSimilar patientsLowest quartileImproved outcomesHospitalPatients