2008
Noninvasive Detection of Risk for Emotion Provoked Myocardial Ischemia
Burg MM, Graeber B, Vashist A, Collins D, Earley C, Liu J, Lampert R, Soufer R. Noninvasive Detection of Risk for Emotion Provoked Myocardial Ischemia. Psychosomatic Medicine 2008, 71: 14-20. PMID: 18941131, PMCID: PMC2739989, DOI: 10.1097/psy.0b013e318187c035.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngerAngiotensin-Converting Enzyme InhibitorsBlood PressureCoronary DiseaseEpinephrineFemaleHeart RateHumansImagery, PsychotherapyMaleManometryMiddle AgedMyocardial IschemiaNorepinephrinePlethysmographyPredictive Value of TestsPulsatile FlowRiskSensitivity and SpecificityStress, PsychologicalTomography, Emission-Computed, Single-PhotonVascular ResistanceConceptsPeripheral arterial tonometryCoronary artery diseasePAT ratioMyocardial ischemiaMajor adverse cardiac eventsStable coronary artery diseaseLower PAT ratioMental stress ischemiaAdverse cardiac eventsNew perfusion defectsCT myocardial perfusionSensitivity/specificityStress ischemiaArterial tonometryCardiac eventsArtery diseaseBlood pressureACE inhibitionPerfusion defectsHeart rateMyocardial perfusionPatientsEnzyme inhibitorsClinical settingIschemia
1998
Effects of Mental Stress on Left Ventricular and Peripheral Vascular Performance in Patients With Coronary Artery Disease
Jain D, Shaker M, Burg M, Wackers F, Soufer R, Zaret B. Effects of Mental Stress on Left Ventricular and Peripheral Vascular Performance in Patients With Coronary Artery Disease. Journal Of The American College Of Cardiology 1998, 31: 1314-1322. PMID: 9581726, DOI: 10.1016/s0735-1097(98)00092-8.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionPeripheral vascular resistanceCoronary artery diseaseRate-pressure productStress-induced fallSystolic blood pressureArtery diseaseBlood pressureCardiac outputHeart rateMental stressGroup IHemodynamic variablesAnger recallGroup IIMental stressorsEnd-systolic ventricular elastanceMental stress-induced changesSemisupine bicycle exerciseGroup II patientsComparable increaseDiastolic blood pressureVentricular ejection fractionExercise-induced changesVascular resistance
1996
Comparison of Nifedipine GITS and Hydrochlorothiazide in the Management of Elderly Patients with Stage I–III Diastolic Hypertension*
Dey H, Soufer R, Hoffer P, Wackers F, Black H. Comparison of Nifedipine GITS and Hydrochlorothiazide in the Management of Elderly Patients with Stage I–III Diastolic Hypertension*. American Journal Of Hypertension 1996, 9: 598-606. PMID: 8783785, DOI: 10.1016/0895-7061(96)00168-9.Peer-Reviewed Original ResearchConceptsNifedipine gastrointestinal therapeutic systemGastrointestinal therapeutic systemDiastolic blood pressureBlood pressureDiastolic hypertensionStage IVentricular massCardiovascular functionTreatment differencesGoal diastolic blood pressureSignificant blood pressure reductionWeek placebo washout phasePlacebo washout phaseWeek maintenance phaseBlood pressure reductionGoal blood pressureDiastolic filling rateRenal blood flowGlomerular filtration rateLeft ventricular massBlood urea nitrogenShort-term therapyAdverse side effectsSignificant adverse effectsDiuretic therapy
1993
Role of behavioral and psychological factors in mental stress-induced silent left ventricular dysfunction in coronary artery disease
Burg M, Jain D, Soufer R, Kerns R, Zaret B. Role of behavioral and psychological factors in mental stress-induced silent left ventricular dysfunction in coronary artery disease. Journal Of The American College Of Cardiology 1993, 22: 440-448. PMID: 8335813, DOI: 10.1016/0735-1097(93)90048-6.Peer-Reviewed Original ResearchConceptsSilent left ventricular dysfunctionLeft ventricular dysfunctionCoronary artery diseaseVentricular dysfunctionArtery diseaseBlood pressureChronic stable coronary artery diseaseStable coronary artery diseaseStress thallium-201 imagingMental stressGroup I patientsSilent myocardial ischemiaThallium-201 imagingAbsence of symptomsSerial radionuclide ventriculographyStructured interviewsNonischemic groupEjection fractionI patientsPsychological factorsVentricular indexRadionuclide ventriculographyClinical indicesMyocardial ischemiaReversible defects
1990
Usefulness of verapamil for congestive heart failure associated with abnormal left ventricular diastolic filling and normal left ventricular systolic performance
Setaro J, Zaret B, Schulman D, Black H, Soufer R. Usefulness of verapamil for congestive heart failure associated with abnormal left ventricular diastolic filling and normal left ventricular systolic performance. The American Journal Of Cardiology 1990, 66: 981-986. PMID: 2220622, DOI: 10.1016/0002-9149(90)90937-v.Peer-Reviewed Original ResearchConceptsCongestive heart failureNormal left ventricular systolic performanceLeft ventricular diastolic fillingLeft ventricular systolic performanceVentricular diastolic fillingVentricular systolic performanceDiastolic fillingBlood pressureHeart failureSystolic performanceAbnormal left ventricular diastolic fillingThallium-201 stress scintigraphyAbnormal diastolic fillingEDV/sHeart failure scoreSignificant valvular diseaseMean ejection fractionDiastolic blood pressureSystolic blood pressureLeft ventricular functionPeak filling rateOral verapamilExercise capacityPlacebo valuesSystolic function
1989
Differing responses in right and left ventricular filling, loading and volumes during positive end-expiratory pressure
Schulman D, Biondi J, Matthay R, Zaret B, Soufer R. Differing responses in right and left ventricular filling, loading and volumes during positive end-expiratory pressure. The American Journal Of Cardiology 1989, 64: 772-777. PMID: 2679024, DOI: 10.1016/0002-9149(89)90763-7.Peer-Reviewed Original ResearchConceptsPeak filling rateEnd-diastolic volumeLV end-diastolic volumeEjection fractionLeft ventricularCardiac outputRV volumesLV volumesPositive end-expiratory pressure (PEEP) applicationRight ventricular ejection fractionRV end-diastolic volumePositive end-expiratory pressureGroup 1 patientsLow cardiac outputSystemic vascular resistanceVentricular ejection fractionCoronary artery diseaseLV ejection fractionRV ejection fractionEnd-expiratory pressureFilling rateVascular resistanceArtery diseaseBlood pressureVentricular function