2020
P122. Use of a novel allograft in single- and two-level posterolateral lumbar spinal fusion: two-year clinical and radiographic results from a prospective multicenter study
Daffner S, Bunch J, An H, Burton D, Milam R, Park D, Strenge K, Whang P. P122. Use of a novel allograft in single- and two-level posterolateral lumbar spinal fusion: two-year clinical and radiographic results from a prospective multicenter study. The Spine Journal 2020, 20: s204. DOI: 10.1016/j.spinee.2020.05.520.Peer-Reviewed Original ResearchIliac crest bone graftFusion rateBone graft substituteClinical outcomesSpinal fusionOswestry Disability Index scoresProspective multicenter cohort studyAutologous iliac crest bone graftSTUDY DESIGN/SETTINGIndependent core labPosterolateral lumbar spinal fusionSF-36v2 PCSDisability Index scoresMulticenter cohort studyPosterolateral lumbar fusion surgeryProspective multicenter studyBetter clinical outcomesLumbar fusion surgeryCrest bone graftGold standard graft materialLumbar spinal fusionDESIGN/SETTINGStandard graft materialPosterolateral spinal fusionEndogenous growth factors
2015
Superion® InterSpinous Spacer for treatment of moderate degenerative lumbar spinal stenosis: durable three-year results of a randomized controlled trial
Patel VV, Nunley PD, Whang PG, Haley TR, Bradley WD, Davis RP, Block JE, Geisler FH. Superion® InterSpinous Spacer for treatment of moderate degenerative lumbar spinal stenosis: durable three-year results of a randomized controlled trial. Journal Of Pain Research 2015, Volume 8: 657-662. PMID: 26491369, PMCID: PMC4599047, DOI: 10.2147/jpr.s92633.Peer-Reviewed Original ResearchDegenerative lumbar spinal stenosisLumbar spinal stenosisPrimary composite endpointSpinal stenosisComposite endpointClinical outcomesDrug Administration Investigational Device Exemption trialDisease-specific functional outcomesInvestigational device exemption trialDurable clinical improvementLeg pain severityRandomized study groupsZurich Claudication QuestionnaireProcedure-related complicationsIntermittent neurogenic claudicationTreatment of patientsProportion of subjectsThree-year resultsTreatment of subjectsIndividual patient successNeurogenic claudicationPrimary endpointClinical improvementCorresponding success ratesPain severity
2014
Two-year clinical outcomes of a multicenter randomized controlled trial comparing two interspinous spacers for treatment of moderate lumbar spinal stenosis
Patel VV, Whang PG, Haley TR, Bradley WD, Nunley PD, Miller LE, Block JE, Geisler FH. Two-year clinical outcomes of a multicenter randomized controlled trial comparing two interspinous spacers for treatment of moderate lumbar spinal stenosis. BMC Musculoskeletal Disorders 2014, 15: 221. PMID: 24996648, PMCID: PMC4109165, DOI: 10.1186/1471-2474-15-221.Peer-Reviewed Original ResearchMeSH KeywordsAgedBack PainDisability EvaluationEquipment DesignFemaleHumansLumbar VertebraeMaleOrthopedic ProceduresPain MeasurementPain, PostoperativePatient SatisfactionPredictive Value of TestsProspective StudiesRadiographyRecovery of FunctionSpinal StenosisSurveys and QuestionnairesTime FactorsTreatment OutcomeUnited StatesConceptsModerate lumbar spinal stenosisLumbar spinal stenosisConservative careInterspinous spacerClinical outcomesSpinal stenosisBack functionTwo-year clinical outcomesOswestry Disability IndexPhysical function scoresPatient-reported outcomesInvasive surgical alternativePatient satisfaction scoresExtremity painAxial painDisability IndexComplication dataFunction scoresSurgical alternativePatientsSatisfaction scoresSymptom severityPainIndex levelMulticenter
2009
The Management of Spinal Injuries in Patients With Ankylosing Spondylitis or Diffuse Idiopathic Skeletal Hyperostosis
Whang PG, Goldberg G, Lawrence JP, Hong J, Harrop JS, Anderson DG, Albert TJ, Vaccaro AR. The Management of Spinal Injuries in Patients With Ankylosing Spondylitis or Diffuse Idiopathic Skeletal Hyperostosis. Clinical Spine Surgery A Spine Publication 2009, 22: 77-85. PMID: 19342927, DOI: 10.1097/bsd.0b013e3181679bcb.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overComorbidityDisability EvaluationFemaleHumansHyperostosis, Diffuse Idiopathic SkeletalMaleMiddle AgedMortalityNeurosurgical ProceduresOutcome Assessment, Health CarePostoperative ComplicationsRadiographyRetrospective StudiesSpinal Cord CompressionSpinal FracturesSpinal InjuriesSpineSpondylitis, AnkylosingTreatment OutcomeConceptsDiffuse idiopathic skeletal hyperostosisIdiopathic skeletal hyperostosisSpinal injuryDISH patientsNeurologic deficitsClinical outcomesAS patientsSkeletal hyperostosisAmerican Spinal Injury Association Impairment ScaleHalo-vest orthosisOverall complication rateHalo-vest immobilizationAppropriate imaging studiesSpinal cord injurySubaxial cervical spineOdom's criteriaNonoperative treatmentComplication rateNeurologic injuryNeurologic statusASIA ARetrospective reviewOperative managementCord injurySingle institution
2007
Clinical applications of BMP-7/OP-1 in fractures, nonunions and spinal fusion
White AP, Vaccaro AR, Hall JA, Whang PG, Friel BC, McKee MD. Clinical applications of BMP-7/OP-1 in fractures, nonunions and spinal fusion. International Orthopaedics 2007, 31: 735-741. PMID: 17962946, PMCID: PMC2266670, DOI: 10.1007/s00264-007-0422-x.Peer-Reviewed Original ResearchConceptsBone morphogenetic protein-7Tibial fracturesSpinal fusionOP-1Bony fusion massDistal tibial fracturesLong bone nonunionOpen tibial fracturesRoute of administrationFuture clinical investigationsUse of BMPLong bone applicationsRecombinant human OP-1Collagen matrix resultsSupportive evidenceScaphoid nonunionClinical outcomesTibial nonunionClinical trialsClinical studiesBone nonunionClinical investigationNew therapeutic applicationsAnimal modelsMorphogenetic protein-7