2020
Safety and efficacy of (+)‐epicatechin in subjects with Friedreich's ataxia: A phase II, open‐label, prospective study
Qureshi M, Patterson M, Clark V, Johnson J, Moutvic M, Driscoll S, Kemppainen J, Huston J, Anderson J, Badley A, Tebben P, Wackel P, Oglesbee D, Glockner J, Schreiner G, Dugar S, Touchette J, Gavrilova R. Safety and efficacy of (+)‐epicatechin in subjects with Friedreich's ataxia: A phase II, open‐label, prospective study. Journal Of Inherited Metabolic Disease 2020, 44: 502-514. PMID: 32677106, DOI: 10.1002/jimd.12285.Peer-Reviewed Original ResearchConceptsCardiac magnetic resonance imagingMagnetic resonance imagingOpen-labelCardiac endpointsLeft ventricular (LV) structureFriedreich Ataxia Rating ScaleImprovement of cardiac functionLV mass indexSingle-center trialFriedreich's ataxiaCompared to baselineAtaxia Rating ScaleNonstatistically significant improvementPhase IIFA diagnosisStatistically significant improvementNeurological outcomeSignificant improvementPediatric subjectsAdverse eventsProspective studyCardiac functionHeart failureCardiac structureEvaluate safety
2016
Bone Pain in a 4-year-old Boy with Chronic Granulomatous Disease and History of Aspergillus pneumonia
Uzodi A, Tebben P, Boyce T. Bone Pain in a 4-year-old Boy with Chronic Granulomatous Disease and History of Aspergillus pneumonia. The Pediatric Infectious Disease Journal 2016, 35: 464-465. PMID: 26967683, DOI: 10.1097/inf.0000000000001042.Peer-Reviewed Case Reports and Technical Notes
1997
Three-Dimensional Computerized Reconstruction Illustration of Incremental Articular Cartilage Thinning
TEBBEN P, POPE T, HINSON G, BATNITZKY S, WETZEL L, DEPAOLIS D, MUNNS S, WILKINSON S, GORDON M. Three-Dimensional Computerized Reconstruction Illustration of Incremental Articular Cartilage Thinning. Investigative Radiology 1997, 32: 475-484. PMID: 9258736, DOI: 10.1097/00004424-199708000-00007.Peer-Reviewed Original ResearchConceptsThinning of articular cartilageArticular cartilageArticular cartilage thinningArticular cartilage reconstructionCartilage thinningVolume of cartilagePorcine knee modelIncrement thinningLimitations of measurement methodsShaved cartilageCartilage regionsCartilage reconstructionKnee modelThickness measurementsAverage errorAverage percent errorMeasurement methodThree-dimensionalAssessment of three-dimensionalDimensional measurementsTwo-dimensionalCartilageReconstructed imagesThicknessError