2018
Chapter 26 Vitamin D and the Kidney
Tebben P, Kumar R. Chapter 26 Vitamin D and the Kidney. 2018, 437-459. DOI: 10.1016/b978-0-12-809965-0.00026-4.ChaptersVitamin D receptorPlasma membrane calciumCalcium transport systemEpithelial calcium channelCalbindin-D28KConservation of calciumPhosphorus transportCalcium channelsEfficiency of calciumPhosphorus reabsorptionCalbindin-D9KVitamin DD receptorProximal nephronMembrane calciumTransport systemD28KPhosphorusNephronKidneyCalbindin
2016
Vitamin D-Mediated Hypercalcemia: Mechanisms, Diagnosis, and Treatment
Tebben P, Singh R, Kumar R. Vitamin D-Mediated Hypercalcemia: Mechanisms, Diagnosis, and Treatment. Endocrine Reviews 2016, 37: 521-547. PMID: 27588937, PMCID: PMC5045493, DOI: 10.1210/er.2016-1070.Peer-Reviewed Original ResearchConceptsVitamin D receptorD receptorVitamin D-mediated hypercalcemiaElevated serum calcium concentrationsAssociated with elevated serumProduction of 1,25-dihydroxyvitamin DSuppressing PTH concentrationsAssociated with malignancyReduced bone densityRenal stone formersSerum calcium concentrationVitamin D metabolitesVitamin D<sub>3</sub>Primary hyperparathyroidismElevated serumPTH concentrationsMonoallelic mutationsClinical featuresCYP24A1 geneD metabolitesGranulomatous diseaseBiochemical diagnosisTumor cellsVitamin DHypercalcemia