2024
Posttraumatic Stress Disorder, Obesity, and Accelerated Epigenetic Aging Among US Military Veterans
Fischer I, Na P, Nagamatsu S, Jeste D, Cabrera-Mendoza B, Montalvo-Ortiz J, Krystal J, Polimanti R, Gelernter J, Pietrzak R. Posttraumatic Stress Disorder, Obesity, and Accelerated Epigenetic Aging Among US Military Veterans. JAMA Psychiatry 2024, 81 PMID: 39476130, PMCID: PMC11581715, DOI: 10.1001/jamapsychiatry.2024.3403.Peer-Reviewed Original ResearchPrevalence, Correlates, and Burden of Subthreshold PTSD in US Veterans.
Fischer I, Na P, Harpaz-Rotem I, Marx B, Pietrzak R. Prevalence, Correlates, and Burden of Subthreshold PTSD in US Veterans. The Journal Of Clinical Psychiatry 2024, 85 PMID: 39480145, DOI: 10.4088/jcp.24m15465.Peer-Reviewed Original ResearchConceptsSubthreshold posttraumatic stress disorderPosttraumatic stress disorderPosttraumatic stress disorder symptom clustersLifetime psychiatric disordersUS veteransUS military veteransSymptom-related distressStress disorderPsychiatric disordersSymptom clustersTreating veteransCriterion AMilitary veteransTraumatic eventsCognitive functionWorking case definitionMental healthCriterion FFunctional impairmentVeteransNationally representative sampleFunctional correlatesDisordersElevated oddsGreater oddsGenes in context: path to more precise risk prediction in psychiatry?
Na P, Pietrzak R, Gelernter J. Genes in context: path to more precise risk prediction in psychiatry? The British Journal Of Psychiatry 2024, 1-2. PMID: 39422146, DOI: 10.1192/bjp.2024.151.Peer-Reviewed Original ResearchLoneliness Trajectories in U.S. Military Veterans: A 3-Year Longitudinal Study of Risk and Protective Factors
Ong A, Cintron D, Rottenberg J, Panaite V, Fischer I, Na P, Jeste D, Pietrzak R. Loneliness Trajectories in U.S. Military Veterans: A 3-Year Longitudinal Study of Risk and Protective Factors. The Journals Of Gerontology Series B 2024, gbae171. PMID: 39390809, DOI: 10.1093/geronb/gbae171.Peer-Reviewed Original ResearchGrowth mixture modelingU.S. military veteransLoneliness trajectoriesMilitary veteransLongitudinal Study of RiskNational Health and ResilienceEarly life adversitySelf-report ratingsProtective factorsWorse cognitive functionMental health concernsPhysical health outcomesHealth concernAdverse childhood experiencesRisk factorsLongitudinal cohort studyStudy of riskNationally representative samplePotential psychosocial riskPromote social connectednessSignificant public health concernVeterans StudyLife adversityThree-step regression analysisCognitive functionT4. RELATIONSHIP OF GENETICALLY-INDEXED PHYSICAL ACTIVITY WITH MENTAL DISORDERS
Galimberti M, Gupta P, Deak J, Dao C, Nitin R, Zhou H, Harrington K, Na P, Topiwala A, Davis L, Gaziano M, Levey D, Stein M, Gelernter J. T4. RELATIONSHIP OF GENETICALLY-INDEXED PHYSICAL ACTIVITY WITH MENTAL DISORDERS. European Neuropsychopharmacology 2024, 87: 157-158. DOI: 10.1016/j.euroneuro.2024.08.314.Peer-Reviewed Original ResearchProtective effect of PAMental health traitsMillion Veteran ProgramEffects of PAGenome-wide association studiesPhysical activityLocal genetic correlationAlcohol consumptionPosttraumatic stress disorderSmoking initiationLeisure time PARelationship of PAUse disorderMental health outcomesPsychiatric disordersSelf-reported informationSubstance useAttention-deficit/hyperactivity disorderGenetic correlation analysisLocal genetic correlation analysisTime PAGenome-wide association study statisticsHealth traitsMR analysisResults PAPersistent distress related to systemic racism among black veterans in the United States
Whealin J, Jegede O, Na P, Haeny A, Pietrzak R. Persistent distress related to systemic racism among black veterans in the United States. Journal Of Affective Disorders 2024, 365: 375-378. PMID: 39147153, DOI: 10.1016/j.jad.2024.08.052.Peer-Reviewed Original ResearchAdverse mental health sequelaeRisk of mental health problemsMilitary veteransIncreased risk of mental health problemsEthnic minority veteransSystemic racismMental health sequelaeMental health problemsUse of self-reportsEthnic minority populationsNationally representative sampleUS military veteransMultinomial logistic regression analysisSignificant emotional burdenStudy periodNon-veteransLogistic regression analysisEmotional burdenMinority veteransBlack veteransUS veteransHealth sequelaeBaseline assessmentHealthcare systemUS populationSuccessful Aging in US Veterans with Mental Disorders: Results From the National Health and Resilience in Veterans Study
Shin J, Fischer I, Na P, Jeste D, Pietrzak R. Successful Aging in US Veterans with Mental Disorders: Results From the National Health and Resilience in Veterans Study. American Journal Of Geriatric Psychiatry 2024 PMID: 39214753, DOI: 10.1016/j.jagp.2024.07.018.Peer-Reviewed Original ResearchGeneralized anxiety disorderPosttraumatic stress disorderMental disordersSomatic symptomsNational Health and ResilienceUS military veteransSuccessful agingAnxiety disordersDepressive disorderUS veteransStress disorderPromote successful agingHigher gratitudeVeterans StudyMilitary veteransInterventions targeting psychosocial factorsOne-in-fiveVeteransMDDDisordersPsychosocial factorsGratitudeNegative associationSymptomsMultivariate logistic regressionPsychological Factors, Physical Conditions, and Functioning Among US Veterans
Fischer I, Na P, Feldman D, Krist A, Kudler H, Jeste D, Pietrzak R. Psychological Factors, Physical Conditions, and Functioning Among US Veterans. JAMA Network Open 2024, 7: e2427382. PMID: 39120905, PMCID: PMC11316230, DOI: 10.1001/jamanetworkopen.2024.27382.Peer-Reviewed Original ResearchCo-occurring Chronic Pain and PTSD Among US Military Veterans: Prevalence, Correlates, and Functioning
Reed D, Fischer I, Williams R, Na P, Pietrzak R. Co-occurring Chronic Pain and PTSD Among US Military Veterans: Prevalence, Correlates, and Functioning. Journal Of General Internal Medicine 2024, 39: 2009-2016. PMID: 38780882, PMCID: PMC11306465, DOI: 10.1007/s11606-024-08803-w.Peer-Reviewed Original ResearchCo-occurring chronic painNationally representative sampleChronic painPosttraumatic stress disorderPsychosocial functioningUS veteransPatient Health Questionnaire-4Representative sampleShort-Form Health Survey-8Prevalence of chronic painNational Health and ResilienceAlcohol Use Disorders Identification TestChronic pain diagnosesDiagnosis of chronic painDisorders Identification TestCognitive Functioning ScaleMeasures of psychosocial functioningUS military veteransSelf-report itemsPosttraumatic Stress Disorder ChecklistHealth careVeterans StudyPain diagnosisFunctional scalesSuicidal Behaviors Questionnaire-RevisedWell-being domains in U.S. military veterans: identifying modifiable factors to promote whole health.
Fischer I, Na P, Feldman D, Krist A, Kudler H, Jeste D, Pietrzak R. Well-being domains in U.S. military veterans: identifying modifiable factors to promote whole health. International Psychogeriatrics 2024, 1-7. PMID: 38770709, DOI: 10.1017/s1041610224000589.Peer-Reviewed Original ResearchU.S. military veteransPromotion of overall healthModifiable factorsWell-beingU.S. Department of Veterans AffairsMilitary veteransDepartment of Veterans AffairsAnalyzed cross-sectional dataModel of healthcareDisease-centred modelNationally representative samplePromote well-beingWell-being domainsWhole healthCross-sectional dataModifiable healthVeterans AffairsSocial supportPsychosocial correlatesOverall healthSocioeconomic well-beingU.S. veteransDisease preventionSocioeconomic domainsRepresentative sampleFunctional significance of posttraumatic growth in U.S. military veterans
Gower T, Fischer I, Tsai J, Kang H, Na P, Tedeschi R, Pietrzak R. Functional significance of posttraumatic growth in U.S. military veterans. Journal Of Affective Disorders 2024, 356: 267-273. PMID: 38614442, DOI: 10.1016/j.jad.2024.04.046.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderPosttraumatic stress disorder symptomsPosttraumatic growthPsychosocial functioningTraumatic eventsTrauma-exposed U.S. veteransNational Health and ResilienceMale veteran samplePost-trauma functioningPattern of findingsRetrospective self-reportsU.S. military veteransVeteran sampleStress disorderVeterans StudyExamined relationsCross-sectional designMilitary veteransNationally representative sampleU.S. veteransAssociated with functionsPhysical functionClinical interventionsPsychosocial characteristicsVeteransProblem Opioid Use Among US Military Veterans: Prevalence, Correlates, and Psychiatric Characteristics
Na P, Petrakis I, Krystal J, Pietrzak R. Problem Opioid Use Among US Military Veterans: Prevalence, Correlates, and Psychiatric Characteristics. Journal Of Addiction Medicine 2024, 18: 313-318. PMID: 38498625, PMCID: PMC11150085, DOI: 10.1097/adm.0000000000001286.Peer-Reviewed Original ResearchInstrumental activities of daily livingInstrumental activities of daily living disabilityLifetime suicide attemptsProblem opioid useUS military veteransUS veteransPsychiatric characteristicsSuicide attemptsMilitary veteransAssociated with black race/ethnicityActivities of daily livingNational Health and ResilienceLifetime alcohol use disorderMental health morbidityPosttraumatic stress disorderMental health disordersAlcohol use disorderNon-Hispanic race/ethnicityMultivariate logistic regression modelNationally representative sampleOpioid useLogistic regression modelsInstrumental activitiesHealth morbidityDaily livingProblematic Alcohol Use Trajectories in U.S. Military Veterans during a Public Health Crisis: Results from a 3-year, Nationally Representative, Longitudinal Study
Na P, Fischer I, Petrakis I, Pietrzak R. Problematic Alcohol Use Trajectories in U.S. Military Veterans during a Public Health Crisis: Results from a 3-year, Nationally Representative, Longitudinal Study. Psychiatric Quarterly 2024, 95: 157-171. PMID: 38319532, PMCID: PMC11521206, DOI: 10.1007/s11126-024-10067-w.Peer-Reviewed Original ResearchConceptsDrug use disordersProblematic alcohol useAlcohol use trajectoriesLow social supportAdverse childhood experiencesAlcohol useGreater household incomeSocial supportUS veteransLongitudinal studyNational Health and ResilienceLatent growth mixture modelingU.S. military veteransHousehold incomeGrowth mixture modelingNon-household membersCOVID-19 pandemicVeterans StudyUse disorderMilitary veteransChildhood experiencesPublic health crisisPsychosocial characteristicsPrevention effortsVeteransGenetic and non-genetic predictors of risk for opioid dependence.
Na P, Deak J, Kranzler H, Pietrzak R, Gelernter J. Genetic and non-genetic predictors of risk for opioid dependence. Psychological Medicine 2024, 54: 1779-1786. PMID: 38317430, PMCID: PMC11132928, DOI: 10.1017/s0033291723003732.Peer-Reviewed Original ResearchPolygenic risk scoresMulti-trait analysis of genome-wide association studyOpioid use disorderPosttraumatic stress disorderPsychosocial/environmental factorsAnalysis of genome-wide association studiesHigher education levelGenome-wide association studiesNon-genetic predictorsEuropean-ancestry adultsEtiology of ODPublic health crisisPsychosocial factorsPolygenic riskMulti-trait analysisEducation levelPsychosocial environmentHousehold incomeRisk scoreAssociation studiesOpioid dependenceDiagnosis of ODLifetime diagnosisYale-PennAssociated with ODFirearm storage practices among military veterans in the United States: Findings from a nationally representative survey
Nichter B, Hill M, Fischer I, Panza K, Kline A, Na P, Norman S, Rowcliffe M, Pietrzak R. Firearm storage practices among military veterans in the United States: Findings from a nationally representative survey. Journal Of Affective Disorders 2024, 351: 82-89. PMID: 38280567, DOI: 10.1016/j.jad.2024.01.179.Peer-Reviewed Original ResearchConceptsFirearm storage practicesContemporary population-based dataNational Health and ResiliencePromote safe firearm storageTrauma exposureAssociated with increased risk of suicidePopulation-based dataCross-sectional designStorage of firearmsAssociated with increased riskRisk of suicideNationally representative surveyDrug use disordersHealthcare professionalsSociodemographic characteristicsVeterans StudyFirearm storageTraumatic brain injuryU.S. veteransService membersMilitary veteransStorage practicesTraining initiativesVeteransRisk status
2023
Functional decline during the COVID‐19 pandemic among U.S. military veterans: Results from the National Health and Resilience in Veterans Study
Morse J, Fischer I, Na P, Afari N, Pietrzak R. Functional decline during the COVID‐19 pandemic among U.S. military veterans: Results from the National Health and Resilience in Veterans Study. International Journal Of Geriatric Psychiatry 2023, 38: e6040. PMID: 38072628, DOI: 10.1002/gps.6040.Peer-Reviewed Original ResearchConceptsAdverse childhood experiencesFunctional declineU.S. military veteransGreater adverse childhood experiencesNational HealthPhysical functioningVeterans StudyIdentification of veteransSubstantial health problemPhysical functional declineMilitary veteransMental functioningU.S. adult populationStress symptomsStrongest correlatePrevalence of veteransProtective psychosocial characteristicsMultivariable analysisPosttraumatic stress symptomsHealth problemsU.S. veteransAdult populationImprovement 1Coronavirus diseaseOlder ageWell-Being of US Military Veterans
Na P, Fischer I, Krist A, Kudler H, Jeste D, Pietrzak R. Well-Being of US Military Veterans. JAMA Network Open 2023, 6: e2346709. PMID: 38060229, PMCID: PMC10704281, DOI: 10.1001/jamanetworkopen.2023.46709.Peer-Reviewed Original ResearchPosttraumatic Growth in U.S. Military Veterans: Results from the National Health and Resilience in Veterans Study
Kang H, Fischer I, Dickinson S, Na P, Tsai J, Tedeschi R, Pietrzak R. Posttraumatic Growth in U.S. Military Veterans: Results from the National Health and Resilience in Veterans Study. Psychiatric Quarterly 2023, 95: 17-32. PMID: 37938492, DOI: 10.1007/s11126-023-10061-8.Peer-Reviewed Original ResearchPosttraumatic growthU.S. military veteransPTSD symptomsTraumatic eventsPosttraumatic stress disorder (PTSD) symptomsPositive psychological changesVeterans StudyMilitary veteransGreater posttraumatic growthTrauma-exposed veteransIntrinsic religiosityPTSD symptom severitySevere PTSD symptomsHigh-risk sampleIntrusive symptomsDisorder symptomsPsychological changesPTG levelsTraumatic experiencesPTSD ChecklistVeteran samplePsychosocial characteristicsSymptom clustersDSM-5Symptom severityPositive personality traits moderate persistent high alcohol consumption, determined by polygenic risk in U.S. military veterans: results from a 10-year, population-based, observational cohort study
Na P, Zhou H, Montalvo-Ortiz J, Cabrera-Mendoza B, Petrakis I, Krystal J, Polimanti R, Gelernter J, Pietrzak R. Positive personality traits moderate persistent high alcohol consumption, determined by polygenic risk in U.S. military veterans: results from a 10-year, population-based, observational cohort study. Psychological Medicine 2023, 53: 7893-7901. PMID: 37642191, DOI: 10.1017/s003329172300199x.Peer-Reviewed Original ResearchAppreciating eudaimonic well-being and positive psychosocial characteristics in mental health research.
Na P. Appreciating eudaimonic well-being and positive psychosocial characteristics in mental health research. International Psychogeriatrics 2023, 35: 537-540. PMID: 37615107, DOI: 10.1017/s104161022300073x.Peer-Reviewed Original Research