2024
Posttraumatic Stress Disorder, Obesity, and Accelerated Epigenetic Aging Among US Military Veterans
Fischer I, Na P, Nagamatsu S, Jeste D, Cabrera-Mendoza B, Montalvo-Ortiz J, Krystal J, Polimanti R, Gelernter J, Pietrzak R. Posttraumatic Stress Disorder, Obesity, and Accelerated Epigenetic Aging Among US Military Veterans. JAMA Psychiatry 2024, 81 PMID: 39476130, PMCID: PMC11581715, DOI: 10.1001/jamapsychiatry.2024.3403.Peer-Reviewed Original ResearchPrevalence, Correlates, and Burden of Subthreshold PTSD in US Veterans.
Fischer I, Na P, Harpaz-Rotem I, Marx B, Pietrzak R. Prevalence, Correlates, and Burden of Subthreshold PTSD in US Veterans. The Journal Of Clinical Psychiatry 2024, 85 PMID: 39480145, DOI: 10.4088/jcp.24m15465.Peer-Reviewed Original ResearchConceptsSubthreshold posttraumatic stress disorderPosttraumatic stress disorderPosttraumatic stress disorder symptom clustersLifetime psychiatric disordersUS veteransUS military veteransSymptom-related distressStress disorderPsychiatric disordersSymptom clustersTreating veteransCriterion AMilitary veteransTraumatic eventsCognitive functionWorking case definitionMental healthCriterion FFunctional impairmentVeteransNationally representative sampleFunctional correlatesDisordersElevated oddsGreater oddsPersistent distress related to systemic racism among black veterans in the United States
Whealin J, Jegede O, Na P, Haeny A, Pietrzak R. Persistent distress related to systemic racism among black veterans in the United States. Journal Of Affective Disorders 2024, 365: 375-378. PMID: 39147153, DOI: 10.1016/j.jad.2024.08.052.Peer-Reviewed Original ResearchAdverse mental health sequelaeRisk of mental health problemsMilitary veteransIncreased risk of mental health problemsEthnic minority veteransSystemic racismMental health sequelaeMental health problemsUse of self-reportsEthnic minority populationsNationally representative sampleUS military veteransMultinomial logistic regression analysisSignificant emotional burdenStudy periodNon-veteransLogistic regression analysisEmotional burdenMinority veteransBlack veteransUS veteransHealth sequelaeBaseline assessmentHealthcare systemUS populationSuccessful Aging in US Veterans with Mental Disorders: Results From the National Health and Resilience in Veterans Study
Shin J, Fischer I, Na P, Jeste D, Pietrzak R. Successful Aging in US Veterans with Mental Disorders: Results From the National Health and Resilience in Veterans Study. American Journal Of Geriatric Psychiatry 2024 PMID: 39214753, DOI: 10.1016/j.jagp.2024.07.018.Peer-Reviewed Original ResearchGeneralized anxiety disorderPosttraumatic stress disorderMental disordersSomatic symptomsNational Health and ResilienceUS military veteransSuccessful agingAnxiety disordersDepressive disorderUS veteransStress disorderPromote successful agingHigher gratitudeVeterans StudyMilitary veteransInterventions targeting psychosocial factorsOne-in-fiveVeteransMDDDisordersPsychosocial factorsGratitudeNegative associationSymptomsMultivariate logistic regressionCo-occurring Chronic Pain and PTSD Among US Military Veterans: Prevalence, Correlates, and Functioning
Reed D, Fischer I, Williams R, Na P, Pietrzak R. Co-occurring Chronic Pain and PTSD Among US Military Veterans: Prevalence, Correlates, and Functioning. Journal Of General Internal Medicine 2024, 39: 2009-2016. PMID: 38780882, PMCID: PMC11306465, DOI: 10.1007/s11606-024-08803-w.Peer-Reviewed Original ResearchCo-occurring chronic painNationally representative sampleChronic painPosttraumatic stress disorderPsychosocial functioningUS veteransPatient Health Questionnaire-4Representative sampleShort-Form Health Survey-8Prevalence of chronic painNational Health and ResilienceAlcohol Use Disorders Identification TestChronic pain diagnosesDiagnosis of chronic painDisorders Identification TestCognitive Functioning ScaleMeasures of psychosocial functioningUS military veteransSelf-report itemsPosttraumatic Stress Disorder ChecklistHealth careVeterans StudyPain diagnosisFunctional scalesSuicidal Behaviors Questionnaire-RevisedProblem Opioid Use Among US Military Veterans: Prevalence, Correlates, and Psychiatric Characteristics
Na P, Petrakis I, Krystal J, Pietrzak R. Problem Opioid Use Among US Military Veterans: Prevalence, Correlates, and Psychiatric Characteristics. Journal Of Addiction Medicine 2024, 18: 313-318. PMID: 38498625, PMCID: PMC11150085, DOI: 10.1097/adm.0000000000001286.Peer-Reviewed Original ResearchInstrumental activities of daily livingInstrumental activities of daily living disabilityLifetime suicide attemptsProblem opioid useUS military veteransUS veteransPsychiatric characteristicsSuicide attemptsMilitary veteransAssociated with black race/ethnicityActivities of daily livingNational Health and ResilienceLifetime alcohol use disorderMental health morbidityPosttraumatic stress disorderMental health disordersAlcohol use disorderNon-Hispanic race/ethnicityMultivariate logistic regression modelNationally representative sampleOpioid useLogistic regression modelsInstrumental activitiesHealth morbidityDaily living
2023
Positive personality traits moderate persistent high alcohol consumption, determined by polygenic risk in U.S. military veterans: results from a 10-year, population-based, observational cohort study
Na P, Zhou H, Montalvo-Ortiz J, Cabrera-Mendoza B, Petrakis I, Krystal J, Polimanti R, Gelernter J, Pietrzak R. Positive personality traits moderate persistent high alcohol consumption, determined by polygenic risk in U.S. military veterans: results from a 10-year, population-based, observational cohort study. Psychological Medicine 2023, 53: 7893-7901. PMID: 37642191, DOI: 10.1017/s003329172300199x.Peer-Reviewed Original ResearchPurpose in life protects against the development of suicidal thoughts and behaviors in U.S. veterans without a history of suicidality: A 10-year, nationally representative, longitudinal study
Fischer I, Nichter B, Feldman D, Na P, Tsai J, Harpaz-Rotem I, Schulenberg S, Pietrzak R. Purpose in life protects against the development of suicidal thoughts and behaviors in U.S. veterans without a history of suicidality: A 10-year, nationally representative, longitudinal study. Journal Of Affective Disorders 2023, 340: 551-554. PMID: 37557988, DOI: 10.1016/j.jad.2023.08.040.Peer-Reviewed Original ResearchConceptsIncident suicidal ideationAlcohol use disorderIncident suicide attemptsCurrent alcohol use disorderHistory of STBSuicidal ideationSuicide attemptsBaseline predictorsDaily livingPopulation-based prospective cohort studySuicidal thoughtsLow purposeCurrent posttraumatic stress disorderProspective cohort studyTraditional risk factorsLower annual household incomeMultivariable regression analysisEvidence-based interventionsUS military veteransPosttraumatic stress disorderAnnual household incomeCohort studyTrauma burdenRisk factorsNational HealthFunctional Disability in US Military Veterans: The Importance of Integrated Whole Health Initiatives.
Meisler A, Gianoli M, Na P, Pietrzak R. Functional Disability in US Military Veterans: The Importance of Integrated Whole Health Initiatives. The Primary Care Companion For CNS Disorders 2023, 25 PMID: 37419488, DOI: 10.4088/pcc.22m03461.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderIADL disabilityFunctional disabilityInstrumental ADLUS veteransCognitive disordersOlder ageDeployment-related injuryUS veteran populationUS military veteransLow incomeADL disabilityChronic painMale sexBlack raceClinical managementRisk factorsNational HealthSleep disordersDaily livingPsychiatric correlatesFunctional capacityVeteran populationDisability riskHealth initiativesLongitudinal Trends in Suicidal Thoughts and Behaviors Among US Military Veterans During the COVID-19 Pandemic
Fischer I, Nichter B, Na P, Norman S, Krystal J, Pietrzak R. Longitudinal Trends in Suicidal Thoughts and Behaviors Among US Military Veterans During the COVID-19 Pandemic. JAMA Psychiatry 2023, 80: 577-584. PMID: 37017978, PMCID: PMC10077136, DOI: 10.1001/jamapsychiatry.2023.0393.Peer-Reviewed Original ResearchConceptsNew-onset suicidal ideationUS military veteransLifetime substance use disorderPast-year suicidal ideationSubstance use disordersSuicidal ideationSuicide planningMilitary veteransUse disordersPsychiatric distressCOVID-19 pandemicSuicidal thoughtsPopulation-based longitudinal studyEvidence-based preventionLongitudinal studyLongitudinal trendsCohort studyNational HealthUS veteransMAIN OUTCOMEVeterans StudySuicide attemptsSuicide riskVulnerable populationsVeterans
2022
Genetic liability to suicidal thoughts and behaviors and risk of suicide attempt in US military veterans: moderating effects of cumulative trauma burden
Nichter B, Koller D, De Angelis F, Wang J, Girgenti M, Na P, Hill M, Norman S, Krystal J, Gelernter J, Polimanti R, Pietrzak R. Genetic liability to suicidal thoughts and behaviors and risk of suicide attempt in US military veterans: moderating effects of cumulative trauma burden. Psychological Medicine 2022, 53: 6325-6333. PMID: 36444557, DOI: 10.1017/s0033291722003646.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresUS military veteransLifetime suicide attemptsSuicide attemptsTrauma exposureTrauma burdenGenetic liabilityMilitary veteransDrug repurposing analysisPopulation-based sampleCumulative trauma exposureLifetime trauma exposureLow trauma exposureSuicide prediction modelsChronic inflammationInflammatory processNervous system developmentRisk scorePsychiatric characteristicsSuicidal behaviorExposure interactionsLarge genome-wide association studiesHigh levelsVeteransSuicidalityFactors Associated With Remission of Suicidal Ideation During the COVID-19 Pandemic: A Population-Based, Longitudinal Study in US Military Veterans.
Herzog S, Nichter B, Hill ML, Na PJ, Norman SB, Pietrzak RH. Factors Associated With Remission of Suicidal Ideation During the COVID-19 Pandemic: A Population-Based, Longitudinal Study in US Military Veterans. The Journal Of Clinical Psychiatry 2022, 83 PMID: 35771973, DOI: 10.4088/jcp.21br14341.Peer-Reviewed Original Research
2021
Prevalence and Trends in Suicidal Behavior Among US Military Veterans During the COVID-19 Pandemic
Nichter B, Hill ML, Na PJ, Kline AC, Norman SB, Krystal JH, Southwick SM, Pietrzak RH. Prevalence and Trends in Suicidal Behavior Among US Military Veterans During the COVID-19 Pandemic. JAMA Psychiatry 2021, 78: 1218-1227. PMID: 34431973, PMCID: PMC8387942, DOI: 10.1001/jamapsychiatry.2021.2332.Peer-Reviewed Original ResearchConceptsUS military veteransCOVID-19 infectionCohort studySuicidal behaviorPast-year suicide ideationRisk factorsMilitary veteransPopulation-based prospective cohort studyCOVID-19 pandemicSuicide ideationSuicide attemptsProspective cohort studyLifetime posttraumatic stress disorderStrong risk factorCOVID-19 public health emergencyLow social supportPosttraumatic stress disorderPublic health emergencyAlcohol use disorder severityUS veteransNational HealthMAIN OUTCOMESuicide attempt historyVeterans StudyCOVID-19-related variablesNew‐onset and exacerbated insomnia symptoms during the COVID‐19 pandemic in US military veterans: A nationally representative, prospective cohort study
McCarthy E, DeViva JC, Na PJ, Pietrzak RH. New‐onset and exacerbated insomnia symptoms during the COVID‐19 pandemic in US military veterans: A nationally representative, prospective cohort study. Journal Of Sleep Research 2021, 31: e13450. PMID: 34327743, PMCID: PMC8420100, DOI: 10.1111/jsr.13450.Peer-Reviewed Original ResearchConceptsClinical insomnia symptomsInsomnia symptomsUS military veteransPandemic-related stressMilitary veteransProspective cohort studyHigh-risk populationInsomnia Severity IndexCOVID-19 pandemicPosttraumatic stress disorderPandemic-related factorsChest painCohort studyUS veteransNational HealthRepresentative sampleSubthreshold insomniaVeterans StudySymptomsIsolation restrictionsStress disorderMental healthTreatment effortsSeverity IndexPotential targetMental health and suicidal ideation in US military veterans with histories of COVID-19 infection
Na P, Tsai J, Harpaz-Rotem I, Pietrzak R. Mental health and suicidal ideation in US military veterans with histories of COVID-19 infection. BMJ Military Health 2021, 168: 15-19. PMID: 34035155, PMCID: PMC8154290, DOI: 10.1136/bmjmilitary-2021-001846.Peer-Reviewed Original ResearchConceptsStrong independent predictorUS military veteransSuicidal ideationIndependent predictorsCOVID-19COVID-related stressorsInternalising disordersPsychiatric conditionsProtective factorsMilitary veteransCOVID-19 infectionLogistic regression analysisPsychiatric symptom severityLower household incomeCurrent suicidal ideationSubstance use problemsProspective cohortMultivariable analysisTrauma burdenPositive screenUS veteransNational HealthPsychiatric symptomsPsychiatric disordersVeterans Study