2001
Glycosylation and the Immune System
Rudd P, Elliott T, Cresswell P, Wilson I, Dwek R. Glycosylation and the Immune System. Science 2001, 291: 2370-2376. PMID: 11269318, DOI: 10.1126/science.291.5512.2370.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigen PresentationAntigen-Antibody ReactionsAntigen-Presenting CellsAntigens, CD1Carrier ProteinsCollectinsComplement System ProteinsEndoplasmic ReticulumEpitopesGlycoproteinsGlycosylationHistocompatibility AntigensHumansImmune SystemImmunoglobulinsPolysaccharidesProtein FoldingT-LymphocytesViral Envelope ProteinsConceptsImmune systemMajor histocompatibility complex antigensAntigen-presenting cellsAdaptive immune responsesCellular immune systemHistocompatibility complex antigensHumoral immune systemT cell receptor complexRheumatoid arthritisMannose-binding lectinAutoimmune diseasesCell receptor complexT cellsImmune responseComplex antigensPeptide antigensComplement componentsImmunoglobulin GAntigenKey moleculesReceptor complexSpecific glycoformsGlycoproteinGlycopeptide antigensArthritis
1976
HLA‐B specificities and w4, w6 specificities are on the same polypeptide
Ayres J, Cresswell P. HLA‐B specificities and w4, w6 specificities are on the same polypeptide. European Journal Of Immunology 1976, 6: 794-799. PMID: 63373, DOI: 10.1002/eji.1830061108.Peer-Reviewed Original ResearchMeSH KeywordsAllelesCell LineEpitopesGenesHistocompatibility AntigensHLA AntigensHumansIsoantigensPeptidesConceptsHLA-B7HLA-B12HLA-B determinantsAntigenic determinantsDistinct antigenic determinantsDifferent antigenic determinantsHLA-B specificitiesHLA-B locusHLA-B locus productsSequential immunoprecipitation experimentsLymphoblastoid cell linesAntigen poolCell linesLocus productsHunter reagentSpecificityImmunoprecipitation experimentsPapain digestionDeterminantsDiallelic systemAlloantiseraSame polypeptideHLA antigens: rabbit antisera reacting with all A series or all B series specificities
Cresswell P, Ayres J. HLA antigens: rabbit antisera reacting with all A series or all B series specificities. European Journal Of Immunology 1976, 6: 82-88. PMID: 786698, DOI: 10.1002/eji.1830060203.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBeta 2-MicroglobulinCross ReactionsCytotoxicity Tests, ImmunologicGenesHistocompatibility AntigensHLA AntigensHumansImmunoglobulin Fab FragmentsIsoantibodiesMolecular WeightRabbitsConceptsCytotoxicity of HLAHLA alloantiseraHLA antigensA2 substanceHuman peripheral blood lymphocytesPeripheral blood lymphocytesComplement-mediated cytotoxicityType of serumHLA-B12HLA-A2Blood lymphocytesHLA-B7Beta 2microglobulinHLAFragments of rabbitHLA lociCultured cell linesAntigenic determinantsAllelic productsRabbitsCell linesImmune precipitationRabbit antiserumAntigenAntiserum
1975
Purification of papain-solubilized histocompatibility antigens from a cultured human lymphoblastoid line, RPMI 4265.
Turner M, Cresswell P, Parham P, Strominger J, Mann D, Sanderson A. Purification of papain-solubilized histocompatibility antigens from a cultured human lymphoblastoid line, RPMI 4265. Journal Of Biological Chemistry 1975, 250: 4512-4519. PMID: 1141219, DOI: 10.1016/s0021-9258(19)41332-x.Peer-Reviewed Original ResearchConceptsSodium dodecyl sulfate gel electrophoresisSephadex GDodecyl sulfate gel electrophoresisSulfate gel electrophoresisDiethylaminoethylcellulose columnSingle bandCharge heterogeneityM ureaPreparationDEAE-cellulose columnChromatographyM KClSeparationGel electrophoresisMultiple bandsColumnSialic acid
1974
The Immunoglobulin‐Like Structure of Human Histocompatibility Antigens
Strominger J, Cresswell P, Grey H, Humphreys R, Mann D, Mccune J, Parham P, Robb R, Sanderson A, Springer T, Terhorst C, Turner M. The Immunoglobulin‐Like Structure of Human Histocompatibility Antigens. Immunological Reviews 1974, 21: 126-143. PMID: 4139785, DOI: 10.1111/j.1600-065x.1974.tb01549.x.Peer-Reviewed Original ResearchAntigen-Antibody ComplexBeta-GlobulinsCarbon RadioisotopesCell LineCell MembraneCells, CulturedChromatographyChromatography, GelDetergentsElectrophoresisHistocompatibility AntigensImmune SeraImmunoglobulinsIodine RadioisotopesIsoantibodiesIsoelectric FocusingLymphocyte ActivationLymphocytesMolecular WeightNeuraminidasePapainTritiumImmunological Identity of the Small Subunit of HL-A Antigens and β2-Microglobulin and Its Turnover on the Cell Membrane
Cresswell P, Springer T, Strominger J, Turner M, Grey H, Kubo R. Immunological Identity of the Small Subunit of HL-A Antigens and β2-Microglobulin and Its Turnover on the Cell Membrane. Proceedings Of The National Academy Of Sciences Of The United States Of America 1974, 71: 2123-2127. PMID: 4134761, PMCID: PMC388399, DOI: 10.1073/pnas.71.5.2123.Peer-Reviewed Original ResearchPapain-solubilized HL-A Antigens CHROMATOGRAPHIC AND ELECTROPHORETIC STUDIES OF THE TWO SUBUNITS FROM DIFFERENT SPECIFICITIES
Cresswell P, Robb R, Turner M, Strominger J. Papain-solubilized HL-A Antigens CHROMATOGRAPHIC AND ELECTROPHORETIC STUDIES OF THE TWO SUBUNITS FROM DIFFERENT SPECIFICITIES. Journal Of Biological Chemistry 1974, 249: 2828-2832. PMID: 4828322, DOI: 10.1016/s0021-9258(19)42705-1.Peer-Reviewed Original Research
1973
THE SMALL SUBUNIT OF HL-A ANTIGENS IS ß2-MICROGLOBULIN
Grey H, Kubo R, Colon S, Poulik M, Cresswell P, Springer T, Turner M, Strominger J. THE SMALL SUBUNIT OF HL-A ANTIGENS IS ß2-MICROGLOBULIN. Journal Of Experimental Medicine 1973, 138: 1608-1612. PMID: 4128442, PMCID: PMC2139471, DOI: 10.1084/jem.138.6.1608.Peer-Reviewed Original ResearchPapain-Solubilized HL-A Antigens from Cultured Human Lymphocytes Contain Two Peptide Fragments
Cresswell P, Turner M, Strominger J. Papain-Solubilized HL-A Antigens from Cultured Human Lymphocytes Contain Two Peptide Fragments. Proceedings Of The National Academy Of Sciences Of The United States Of America 1973, 70: 1603-1607. PMID: 4514327, PMCID: PMC433551, DOI: 10.1073/pnas.70.5.1603.Peer-Reviewed Original ResearchMeSH KeywordsAntigen-Antibody ComplexBuffersCells, CulturedCentrifugation, Density GradientChromatography, GelElectrophoresis, Polyacrylamide GelGlucosamineGlycopeptidesHistocompatibility AntigensHumansIsotope LabelingLymphocytesMannoseMolecular WeightPapainPeptidesSodium Dodecyl SulfateSolubilityTritium