2001
Role of NHE isoforms in mediating bicarbonate reabsorption along the nephron
Wang T, Hropot M, Aronson P, Giebisch G. Role of NHE isoforms in mediating bicarbonate reabsorption along the nephron. American Journal Of Physiology. Renal Physiology 2001, 281: f1117-f1122. PMID: 11704563, DOI: 10.1152/ajprenal.2001.281.6.f1117.Peer-Reviewed Original ResearchConceptsLoop of HenleHOE 694Proximal tubulesAddition of ethylisopropylamilorideDistal convoluted tubuleBicarbonate reabsorptionConvoluted tubulesSitu microperfusionRat kidneySignificant inhibitionNHE isoformsHenlePredominant isoformTubulesNHE3Functional roleInhibitionNHE2Apical membraneIsoformsApical isoformKidneyMicroperfusionEthylisopropylamilorideNephron
1992
Immunocytochemical characterization of Na(+)-H+ exchanger isoform NHE-1 in rabbit kidney
Biemesderfer D, Reilly RF, Exner M, Igarashi P, Aronson PS. Immunocytochemical characterization of Na(+)-H+ exchanger isoform NHE-1 in rabbit kidney. American Journal Of Physiology 1992, 263: f833-f840. PMID: 1279986, DOI: 10.1152/ajprenal.1992.263.5.f833.Peer-Reviewed Original ResearchConceptsNHE-1 proteinNHE-1Rabbit kidneyDistal convoluted tubuleMultiple nephron segmentsThick ascending limbWestern blot analysisRenal cortexRabbit renal cortexConvoluted tubulesProximal tubulesAscending limbRabbit nephronTubule cellsGuinea pigsLLC-PK1 cellsNephron segmentsIndirect immunofluorescenceKidneyImmunocytochemical characterizationPrincipal cellsExchanger isoformsBlot analysisFusion proteinAntibodies