The effect of inhaled nitric oxide in acute respiratory distress syndrome in children and adults: a Cochrane Systematic Review with trial sequential analysis
Karam O, Gebistorf F, Wetterslev J, Afshari A. The effect of inhaled nitric oxide in acute respiratory distress syndrome in children and adults: a Cochrane Systematic Review with trial sequential analysis. Anaesthesia 2016, 72: 106-117. PMID: 27762438, DOI: 10.1111/anae.13628.Peer-Reviewed Original ResearchMeSH KeywordsAcute Lung InjuryAdministration, InhalationBiasBronchodilator AgentsHumansNitric OxideRandomized Controlled Trials as TopicRespiratory Distress SyndromeInhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adults
Gebistorf F, Karam O, Wetterslev J, Afshari A. Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adults. 2016, 2018: cd002787. PMID: 27347773, PMCID: PMC6464789, DOI: 10.1002/14651858.cd002787.pub3.Peer-Reviewed Original ResearchConceptsAcute respiratory distress syndromeAcute hypoxaemic respiratory failureTrial sequential analysisEffects of iNORespiratory distress syndromeINO groupControl groupDistress syndromeNitric oxideRisk ratioSecondary objectiveHypoxaemic respiratory failureTrial methodological componentsVentilator-free daysCochrane Central RegisterPrimary outcome measureEffect of administrationLength of stayRisk of biasConfidence intervalsAllied Health LiteratureSearch of MEDLINELevel of evidenceEffects of interventionsNitric oxide results