2023
Passive transfer of alloantibodies through breast milk as a mediator of hemolytic anemia
Abels E, Jacobs J, Prior D, Willets L, Sostin N, Tormey C, Binns T. Passive transfer of alloantibodies through breast milk as a mediator of hemolytic anemia. Transfusion 2023, 63: 2188-2196. PMID: 37706556, DOI: 10.1111/trf.17548.Peer-Reviewed Original ResearchConceptsMaternal breast milkBreast milkNeonatal circulationRed blood cellsPassive transferAntiviral IgG antibodiesResolution of anemiaPaucity of dataNeonatal red blood cellsIntravenous immunoglobulinMaternal alloantibodiesMaternal antibodiesPlacental transferRBC antibodiesIgG antibodiesHemolytic diseaseHemolytic anemiaPlasma titersAlloantibodiesHDFNBlood cellsAntibodiesSignificant decreasePatientsAnemiaWarm autoantibodies mimicking alloantibodies: Three cases of autoantibodies with unusual antigenic specificity
Jacobs J, Binns T, Abels E, Campos J, Elkabbani R, Kress A, Sostin N, Tormey C. Warm autoantibodies mimicking alloantibodies: Three cases of autoantibodies with unusual antigenic specificity. American Journal Of Clinical Pathology 2023, 160: 561-565. PMID: 37598315, DOI: 10.1093/ajcp/aqad095.Peer-Reviewed Original ResearchConceptsWarm autoantibodiesRed blood cellsAntigenic specificityCase of autoantibodiesCase 1Autoimmune hemolytic anemiaDirect antiglobulin testRBC transfusionPregnant womenTransfusion reactionsAntiglobulin testHemolytic anemiaAutoantibodiesRBC antigensAntibody detectionRBC unitsRare reportsBlood cellsCase 2Immunohematologic testingSignificant hemolysisRhD typingCase 3AlloantibodiesAutoantiPregnant patients with sickle cell disease and hyperhemolysis requiring intrauterine transfusion: A challenging clinical scenario
Abels E, Binns T, Sostin N, Stendahl K, Tormey C, Jacobs J. Pregnant patients with sickle cell disease and hyperhemolysis requiring intrauterine transfusion: A challenging clinical scenario. Pediatric Blood & Cancer 2023, 70: e30428. PMID: 37194476, DOI: 10.1002/pbc.30428.Peer-Reviewed Case Reports and Technical NotesHemolytic disease of the fetus and newborn mediated by anti-Dia in a U.S. hospital
Jacobs J, Abels E, Binns T, Tormey C, Sostin N. Hemolytic disease of the fetus and newborn mediated by anti-Dia in a U.S. hospital. Immunohematology 2023, 39: 32-34. PMID: 37017601, DOI: 10.21307/immunohematology-2023-006.Peer-Reviewed Case Reports and Technical NotesConceptsHemolytic diseaseCases of HDFNU.S. hospitalsHemolytic transfusion reactionsDirect antiglobulin testNeonatal bilirubin levelsSouth American descentAntibody detection testsLow-prevalence antigensU.S. patient populationNear universal absenceHDFN casesBilirubin levelsPatient populationTransfusion reactionsAntiglobulin testUnexpected causeHispanic ethnicityBlood group systemAntigenAntibodiesHDFNHospitalFetusesDiseaseWarm autoimmune hemolytic anemia with anti‐Jka specificity following babesiosis masquerading as a delayed hemolytic transfusion reaction
Jacobs J, Abels E, Binns T, Tormey C, Sostin N. Warm autoimmune hemolytic anemia with anti‐Jka specificity following babesiosis masquerading as a delayed hemolytic transfusion reaction. Transfusion 2023, 63: 872-876. PMID: 36648131, DOI: 10.1111/trf.17252.Peer-Reviewed Case Reports and Technical NotesConceptsWarm autoimmune hemolytic anemiaDirect antiglobulin testAutoimmune hemolytic anemiaHemolytic transfusion reactionsRed blood cellsRBC transfusionTransfusion reactionsHemolytic anemiaKidd antigensPositive direct antiglobulin testDevelopment of autoantibodiesBabesia microti infectionImmunohematology reference laboratoryColumn agglutination technologyAnti-JkUndetectable parasitemiaAutoantibody statusWarm autoantibodiesRBC antibodiesMicroti infectionAntiglobulin testAntigen specificityAutoantibodiesHealthcare providersAntibody detection
2022
State of the Evidence: Drug Removal via Apheresis
Binns T, Sostin N, Tormey C. State of the Evidence: Drug Removal via Apheresis. Transfusion Medicine Reviews 2022, 37: 16-20. PMID: 36604194, DOI: 10.1016/j.tmrv.2022.12.003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAlloimmunization following antigen‐negative red blood cell transfusion
Jacobs J, Binns T, Abels E, Iyer K, Villalba C, Verma A, Sostin N, Tormey C. Alloimmunization following antigen‐negative red blood cell transfusion. Transfusion 2022, 63: 430-434. PMID: 36458330, DOI: 10.1111/trf.17208.Peer-Reviewed Case Reports and Technical NotesConceptsTransfusion of RBCsRed blood cell transfusionRed blood cell alloimmunizationPrevious antigen exposureBlood cell transfusionAlloantibody specificitiesCell transfusionRBC transfusionAntigen exposureRBC alloantibodiesAntigenic stimulusDetectable titersAntigenic stimulationMyeloid neoplasmsTransfusionAlloantibodiesAlloimmunizationParticular antigenPrior exposureStimulatory eventsExact mechanismCorresponding antibodiesRBCsExposurePregnancyIncidental Discovery of a Patient with the Bombay Phenotype
Jacobs JW, Horstman E, Gisriel SD, Tormey CA, Sostin N. Incidental Discovery of a Patient with the Bombay Phenotype. Lab Medicine 2022, 54: e14-e17. PMID: 35776424, DOI: 10.1093/labmed/lmac075.Peer-Reviewed Case Reports and Technical NotesConceptsRed blood cellsH antigensIncidental discoveryAcute hemolytic transfusion reactionBombay phenotypeHemolytic transfusion reactionsAmerican hospital systemRare blood typesTransfusion reactionsCompatible bloodB antigensBlood typeAntigenBlood cellsHospital systemABO phenotypingBlood phenotypeABO systemPatientsPara-Bombay phenotypeType OH deficiencyPhenotypeIll effectsIndividuals
2018
Comparison of Biomarker Expressivity in the Esophageal Metaplasia-Dysplasia-Adenocarcinoma Sequence
Sostin N, Sostin O, Fiedler P, Campbell J. Comparison of Biomarker Expressivity in the Esophageal Metaplasia-Dysplasia-Adenocarcinoma Sequence. American Journal Of Clinical Pathology 2018, 150: s52-s52. DOI: 10.1093/ajcp/aqy090.128.Peer-Reviewed Original ResearchHigh-grade dysplasiaLow-grade dysplasiaHigh-risk lesionsEsophageal adenocarcinomaIHC stainsCyclin D1Invasive adenocarcinomaTissue microarrayMucosal biopsy specimensDepartment of PathologyP53 staining patternMucosal biopsiesDanbury HospitalHistologic diagnosisBiopsy specimensEsophageal dysplasiaMetaplasia-dysplasiaImmunohistochemical stainsClinical utilityBiopsy tissueLethal cancersPositive stainingAdenocarcinomaAdenocarcinoma sequenceIntensity staining
2017
Small Bowel Intussusception Secondary to Inflammatory Fibroid Polyp of the Ileum
Sostin N, Baqai S, Bhalla A, Orlina J, El-Fanek H. Small Bowel Intussusception Secondary to Inflammatory Fibroid Polyp of the Ileum. The American Journal Of Gastroenterology 2017, 112: s1347. DOI: 10.14309/00000434-201710001-02472.Peer-Reviewed Original ResearchA Unique Case of Gastric Calcinosis Secondary to Complete Hypoparathyroidism
Sostin O, Sostin N, Appel C, El-Fanek H. A Unique Case of Gastric Calcinosis Secondary to Complete Hypoparathyroidism. The American Journal Of Gastroenterology 2017, 112: s1445. DOI: 10.14309/00000434-201710001-02639.Peer-Reviewed Original Research
2016
NSAIDs Use after Breast Cancer Diagnosis Improves Relapse-Free and Overall Survival: Retrospective Pilot Study
Sostin N, He S, Sostin O, Troxell M. NSAIDs Use after Breast Cancer Diagnosis Improves Relapse-Free and Overall Survival: Retrospective Pilot Study. American Journal Of Clinical Pathology 2016, 146: 315. DOI: 10.1093/ajcp/aqw159.086.Peer-Reviewed Original Research