2020
Implementation of the TaperGuard™ endotracheal tube in an unselected surgical population to reduce postoperative pneumonia
Martini RP, Yanez ND, Treggiari MM, Tekkali P, Soelberg C, Aziz MF. Implementation of the TaperGuard™ endotracheal tube in an unselected surgical population to reduce postoperative pneumonia. BMC Anesthesiology 2020, 20: 211. PMID: 32838740, PMCID: PMC7446207, DOI: 10.1186/s12871-020-01117-4.Peer-Reviewed Original ResearchConceptsPostoperative pneumoniaSubgroup of patientsBaseline cohortSurgical patientsIntervention cohortEndotracheal intubationOdds ratioNational Surgical Quality Improvement ProjectSurgical Quality Improvement ProjectUnselected surgical populationUnadjusted odds ratioHigh-risk populationPatient-level dataRisk of ventilatorQuality improvement projectInterrupted time series designElectronic health recordsHospital mortalityVAP bundleSurgical populationPatient characteristicsPneumonia riskHistoric cohortHospital admissionFurther risk reduction
2016
Randomized Pilot Trial of Two Modified Endotracheal Tubes To Prevent Ventilator-associated Pneumonia
Deem S, Yanez D, Sissons-Ross L, Broeckel JA, Daniel S, Treggiari M. Randomized Pilot Trial of Two Modified Endotracheal Tubes To Prevent Ventilator-associated Pneumonia. Annals Of The American Thoracic Society 2016, 13: 72-80. PMID: 26523433, PMCID: PMC4722846, DOI: 10.1513/annalsats.201506-346oc.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedEquipment DesignEquipment SafetyFemaleHumansIntubation, IntratrachealMaleMiddle AgedPilot ProjectsPneumonia, Ventilator-AssociatedTreatment OutcomeConceptsEndotracheal tubeTracheal colonizationChest radiograph criteriaOccurrence of VAPPrevention of VAPCoprimary end pointsSerious adverse eventsInstitutional review board approvalEmergency endotracheal intubationStandard endotracheal tubeMajority of intubationsReview board approvalModified Endotracheal TubeSafety concernsAdverse eventsVAP preventionEndotracheal intubationSubglottic secretionsEmergency intubationClinical trialsClinical signsNosocomial infectionsPilot trialStudy groupHospital setting
2014
Variation in Tracheal Reintubations Among Patients Undergoing Cardiac Surgery Across Washington State Hospitals
Khandelwal N, Dale CR, Benkeser DC, Joffe AM, Yanez ND, Treggiari MM. Variation in Tracheal Reintubations Among Patients Undergoing Cardiac Surgery Across Washington State Hospitals. Journal Of Cardiothoracic And Vascular Anesthesia 2014, 29: 551-559. PMID: 25802193, PMCID: PMC4427545, DOI: 10.1053/j.jvca.2014.11.009.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAirway ExtubationAirway ManagementCardiac Surgical ProceduresCohort StudiesCoronary Artery BypassCritical CareDatabases, FactualFemaleHealth SurveysHumansIntubation, IntratrachealMaleMiddle AgedRetrospective StudiesRisk FactorsSocioeconomic FactorsTreatment FailureTreatment OutcomeWashingtonConceptsIntensive care unitCardiac surgeryWashington State hospitalsNonfederal hospitalsState HospitalAcute care daysGreater hospital volumeOdds of reintubationCoronary artery bypassRetrospective cohort studyPatient-level characteristicsMultivariate logistic regressionSignificant heterogeneityValvular surgeryArtery bypassCohort studyHospital factorsHospital volumePatient characteristicsTracheal reintubationCare unitProcedure characteristicsHospital characteristicsCare daysReintubationPrediction of Early and Late Re-intubation: Is It a Crossed or Separate Line?—Reply
Treggiari MM, Yanez ND. Prediction of Early and Late Re-intubation: Is It a Crossed or Separate Line?—Reply. Respiratory Care 2014, 59: e103-e104. PMID: 24970915, DOI: 10.4187/respcare.03455.Peer-Reviewed Original ResearchIn vitro evaluation of diffusion of lidocaine and alkalinized lidocaine through the polyurethane membrane of the endotracheal tube
Estebe JP, Treggiari M, Richebe P, Joffe A, Chevanne F, Le Corre P. In vitro evaluation of diffusion of lidocaine and alkalinized lidocaine through the polyurethane membrane of the endotracheal tube. Anaesthesia Critical Care & Pain Medicine 2014, 33: e73-e77. PMID: 24582110, DOI: 10.1016/j.annfar.2013.12.022.Peer-Reviewed Original Research
2013
Predictors of Reintubation in Critically Ill Patients
Miu T, Joffe AM, Yanez ND, Khandelwal N, Dagal AH, Deem S, Treggiari MM. Predictors of Reintubation in Critically Ill Patients. Respiratory Care 2013, 59: 178-185. PMID: 23882103, DOI: 10.4187/respcare.02527.Peer-Reviewed Original ResearchMeSH KeywordsAdultAPACHECohort StudiesFemaleHumansIntensive Care UnitsIntubation, IntratrachealLogistic ModelsMalePrognosisRespiration, ArtificialRetreatmentRisk FactorsROC CurveConceptsAcute Physiology Score IIDiastolic blood pressureExtubation failureScore IIBlood pressureMinute ventilationAdmission Simplified Acute Physiology Score IISimplified Acute Physiology Score IIRapid shallow breathing indexMultivariable logistic regression analysisPredictors of reintubationTertiary care centerShallow breathing indexAdditional independent predictorsBivariate logistic regression modelLogistic regression analysisLogistic regression modelsICU extubationExtubation successICU admissionBaseline characteristicsCohort studyIll patientsIndependent predictorsBreathing index
2012
Occurrence and Complications of Tracheal Reintubation in Critically Ill Adults
Menon N, Joffe AM, Deem S, Yanez ND, Grabinsky A, Dagal AH, Daniel S, Treggiari MM. Occurrence and Complications of Tracheal Reintubation in Critically Ill Adults. Respiratory Care 2012, 57: 1555-1563. PMID: 22324979, DOI: 10.4187/respcare.01617.Peer-Reviewed Original ResearchConceptsDifficult airwayHigh mortalityHospital stayAdmission severity scoresIll adult patientsComplications of intubationAirway management techniquesHospital mortalityInitial intubationMedian ICURespiratory failureTracheal extubationAdult patientsBaseline characteristicsCohort studyIll adultsIll patientsTracheal reintubationDifficult intubationSeverity scoreSubsequent intubationRisk factorsPatient costsReintubationRelative odds
2011
The Second-Generation Air-Q® Intubating Laryngeal Mask for Airway Maintenance during Anaesthesia in Adults: A Report of the First 70 Uses
Joffe AM, Liew EC, Galgon RE, Viernes D, Treggiari MM. The Second-Generation Air-Q® Intubating Laryngeal Mask for Airway Maintenance during Anaesthesia in Adults: A Report of the First 70 Uses. Anaesthesia And Intensive Care 2011, 39: 40-45. PMID: 21375088, DOI: 10.1177/0310057x1103900106.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnesthesia, GeneralEquipment DesignFemaleFiber Optic TechnologyHumansIntubation, IntratrachealLaryngeal MasksMaleRetrospective StudiesConceptsAirway leak pressureLaryngeal airwayAirway maintenancePrimary airwayLeak pressureMedian (IQR [range]) airway leak pressureIntubating Laryngeal MaskPostoperative throat complaintsSupraglottic airway deviceMild sore throatUnanticipated difficult airwayInitial clinical experienceDuration of useEase of insertionOropharyngeal morbidityThroat complaintsRetrospective reviewSore throatDifficult airwayLaryngeal maskAirway devicesInsertion attemptsAirwayClinical experienceIntubation
2010
New endotracheal tubes designed to prevent ventilator-associated pneumonia: do they make a difference?
Deem S, Treggiari MM. New endotracheal tubes designed to prevent ventilator-associated pneumonia: do they make a difference? Respiratory Care 2010, 55: 1046-55. PMID: 20667152.Peer-Reviewed Original ResearchMeSH KeywordsBiofilmsHumansIntention to Treat AnalysisIntubation, IntratrachealPatient SelectionPneumonia, Ventilator-AssociatedSuctionConceptsEndotracheal tubeVAP preventionVentilator-associated pneumoniaNew endotracheal tubeImportant patient outcomesInfection control methodsModified Endotracheal TubeCost-effectiveness dataProper patient positioningOral hygienePatient outcomesNosocomial infectionsInsufficient evidencePatient careStrong recommendationsImportant safety concernsPatient positioningMeticulous attentionPneumoniaSuch interventionsMicroaspirationSafety concernsMultifaceted approachPreventionFuture studies
2005
Factors Associated with Failure of Noninvasive Positive Pressure Ventilation in the Emergency Department
Merlani PG, Pasquina P, Granier JM, Treggiari M, Rutschmann O, Ricou B. Factors Associated with Failure of Noninvasive Positive Pressure Ventilation in the Emergency Department. Academic Emergency Medicine 2005, 12: 1206-1215. PMID: 16293895, DOI: 10.1197/j.aem.2005.07.018.Peer-Reviewed Original ResearchMeSH KeywordsAgedEmergency Service, HospitalFemaleHospitalizationHumansIntubation, IntratrachealMaleMultivariate AnalysisOutcome and Process Assessment, Health CarePositive-Pressure RespirationPulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk FactorsSensitivity and SpecificitySurvival AnalysisSwitzerlandTreatment FailureConceptsNoninvasive positive pressure ventilationFailure of NPPVAcute respiratory failurePositive pressure ventilationEmergency departmentRespiratory rateRespiratory failurePressure ventilationEndotracheal intubationNPPV failureGlasgow Coma Scale scoreSubsequent endotracheal intubationNegative predictive valueED admissionInstitutional protocolFactors AssociatedPatientsPredictive valueScale scoreMultivariate analysisIntubationVentilationFailureHoursDepartment