2017
Process Improvement Initiative for the Perioperative Management of Patients With a Cardiovascular Implantable Electronic Device
Ellis MKM, Treggiari MM, Robertson JM, Rozner MA, Graven PF, Aziz MF, Merkel MJ, Kahl EA, Cohen NA, Stecker EC, Schulman PM. Process Improvement Initiative for the Perioperative Management of Patients With a Cardiovascular Implantable Electronic Device. Anesthesia & Analgesia 2017, 125: 58-65. PMID: 28319519, DOI: 10.1213/ane.0000000000001953.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAgedAged, 80 and overCardiac Surgical ProceduresCardiovascular SystemCohort StudiesDefibrillators, ImplantableFemaleHealth Care CostsHumansMaleMiddle AgedOperating RoomsOutcome and Process Assessment, Health CarePacemaker, ArtificialPatient SafetyPerioperative CarePerioperative PeriodRisk AssessmentTime FactorsConceptsCardiovascular implantable electronic devicesSafe perioperative carePreintervention periodPostintervention periodImplantable electronic devicesPerioperative carePerioperative surgical home modelPrimary end pointCohort of patientsSame eligibility criteriaLarge academic medical centerPatient Safety DatabaseImprovement initiativesAcademic medical centerAdequate patient safetyNew care modelsImproved operating room efficiencyBaseline characteristicsAdverse eventsPerioperative managementPotential confoundersConcurrent cohortDay surgerySurgical proceduresCare model
2016
Pre-diagnostic Sleep Duration and Sleep Quality in Relation to Subsequent Cancer Survival.
Phipps AI, Bhatti P, Neuhouser ML, Chen C, Crane TE, Kroenke CH, Ochs-Balcom H, Rissling M, Snively BM, Stefanick ML, Treggiari MM, Watson NF. Pre-diagnostic Sleep Duration and Sleep Quality in Relation to Subsequent Cancer Survival. Journal Of Clinical Sleep Medicine 2016, 12: 495-503. PMID: 26612513, PMCID: PMC4795275, DOI: 10.5664/jcsm.5674.Peer-Reviewed Original ResearchConceptsWomen's Health InitiativeShort sleep durationSleep characteristicsHazard ratioCancer survivalCancer sitesSleep durationHealth initiativesPrimary invasive cancerCancer-specific survivalConfidence intervalsPoor sleep qualityFrequent snoringStudy armsCox regressionCancer outcomesInvasive cancerCommon cancerWHI participantsPhysical activitySleep qualityElevated riskCancer typesCancerMarital status
2015
Dexmedetomidine Does Not Affect Evoked Potentials During Spine Surgery
Rozet I, Metzner J, Brown M, Treggiari MM, Slimp JC, Kinney G, Sharma D, Lee LA, Vavilala MS. Dexmedetomidine Does Not Affect Evoked Potentials During Spine Surgery. Anesthesia & Analgesia 2015, 121: 492-501. PMID: 26097987, DOI: 10.1213/ane.0000000000000840.Peer-Reviewed Original ResearchMeSH KeywordsAnesthesia, IntravenousAnesthetics, IntravenousDexmedetomidineDouble-Blind MethodEvoked PotentialsEvoked Potentials, MotorEvoked Potentials, SomatosensoryEvoked Potentials, VisualFemaleHumansHypnotics and SedativesIntraoperative Neurophysiological MonitoringMaleMiddle AgedOrthopedic ProceduresPiperidinesPropofolReaction TimeRemifentanilSpineTime FactorsConceptsEffect of dexmedetomidineVisual EPsSpine surgeryEnd pointElective spine surgeryPlacebo-controlled trialPrimary end pointSecondary end pointsLatency N1Motor EPsPlacebo groupStudy drugAdult patientsNormal salineLatency P1DexmedetomidineSomatosensory EPsIRB approvalRelevant dosesEP recordingInformed consentPatientsSurgeryEvoked PotentialsAnesthesiaComparison of train-of-four count by anesthesia providers versus TOF-Watch® SX: a prospective cohort study
Bhananker SM, Treggiari MM, Sellers BA, Cain KC, Ramaiah R, Thilen SR. Comparison of train-of-four count by anesthesia providers versus TOF-Watch® SX: a prospective cohort study. Journal Canadien D'anesthésie 2015, 62: 1089-1096. PMID: 26224034, DOI: 10.1007/s12630-015-0433-9.Peer-Reviewed Original ResearchConceptsTOF-Watch SXTOF countNeuromuscular blockadeReversal agentsAnesthesia providersCohort studyTOF-WatchMethodsThis prospective observational cohort studyAnesthesiologists physical status IIIProspective observational cohort studyDose of rocuroniumObservational cohort studyProspective cohort studyComparison of TrainPremature administrationInadequate dosingElective surgeryBlockadeDoseAmerican SocietyPatientsCountSubjective assessmentProvidersLower counts
2014
Long-Term Survival in Patients With Severe Acute Respiratory Distress Syndrome and Rescue Therapies for Refractory Hypoxemia*
Khandelwal N, Hough CL, Bansal A, Veenstra DL, Treggiari MM. Long-Term Survival in Patients With Severe Acute Respiratory Distress Syndrome and Rescue Therapies for Refractory Hypoxemia*. Critical Care Medicine 2014, 42: 1610-1618. PMID: 24732240, PMCID: PMC4061153, DOI: 10.1097/ccm.0000000000000322.Peer-Reviewed Original ResearchConceptsSevere acute respiratory distress syndromeAcute respiratory distress syndromeRespiratory distress syndromeLong-term survivalRescue therapyProportional hazards modelHospital mortalityDistress syndromeICU admissionHazard ratioHospital dischargeSevere acute respiratory distress syndrome (ARDS) patientsAcute respiratory distress syndrome survivorsConventional treatmentAcute respiratory distress syndrome patientsPaO2/FiO2 ratioBetter long-term survivalRespiratory distress syndrome patientsLevel 1 trauma centerMeeting study inclusion criteriaCox proportional hazards modelHigher hospital mortalityKaplan-Meier methodState death registryStudy inclusion criteriaImproved Analgesia, Sedation, and Delirium Protocol Associated with Decreased Duration of Delirium and Mechanical Ventilation
Dale CR, Kannas DA, Fan VS, Daniel SL, Deem S, Yanez ND, Hough CL, Dellit TH, Treggiari MM. Improved Analgesia, Sedation, and Delirium Protocol Associated with Decreased Duration of Delirium and Mechanical Ventilation. Annals Of The American Thoracic Society 2014, 11: 367-374. PMID: 24597599, PMCID: PMC4028734, DOI: 10.1513/annalsats.201306-210oc.Peer-Reviewed Original ResearchConceptsCAM-ICU assessmentsIntensive care unitMechanical ventilationMedian durationICU stayBenzodiazepine doseSedation protocolPatient assessmentBaseline cohortTrauma-surgical intensive care unitConfusion Assessment Method-ICURichmond Agitation-Sedation Scale scorePrespecified secondary endpointSedation Scale scoreDays of deliriumImproved patient outcomesMultivariable linear regressionBenzodiazepine dosingBenzodiazepine exposureDelirium protocolHospital mortalityPneumonia ratesProtocol cohortRASS assessmentsImproved analgesia
2004
Randomized trial of the effect of antipyresis by metamizol, propacetamol or external cooling on metabolism, hemodynamics and inflammatory response
Gozzoli V, Treggiari MM, Kleger GR, Roux-Lombard P, Fathi M, Pichard C, Romand JA. Randomized trial of the effect of antipyresis by metamizol, propacetamol or external cooling on metabolism, hemodynamics and inflammatory response. Intensive Care Medicine 2004, 30: 401-407. PMID: 14722642, DOI: 10.1007/s00134-003-2087-2.Peer-Reviewed Original ResearchConceptsCytokine concentrationsInflammatory responseEffects of antipyresisMean arterial pressureTertiary university hospitalC-reactive proteinEnergy expenditure indexUndesirable hemodynamic effectsBody temperatureIntravenous propacetamolMetamizol groupPropacetamol groupHemodynamic effectsSurgical ICUArterial pressureIll patientsUrine outputUnstable patientsHemodynamic variablesUniversity HospitalInterleukin-6Physical therapyTreatment groupsPropacetamolMetamizol
2003
Cervical Sympathetic Block to Reverse Delayed Ischemic Neurological Deficits After Aneurysmal Subarachnoid Hemorrhage
Treggiari MM, Romand JA, Martin JB, Reverdin A, Rüfenacht DA, de Tribolet N. Cervical Sympathetic Block to Reverse Delayed Ischemic Neurological Deficits After Aneurysmal Subarachnoid Hemorrhage. Stroke 2003, 34: 961-966. PMID: 12649526, DOI: 10.1161/01.str.0000060893.72098.80.Peer-Reviewed Original ResearchConceptsCervical sympathetic blockAneurysmal subarachnoid hemorrhageSympathetic blockCerebral perfusionNeurological statusCerebral vasospasmSubarachnoid hemorrhageMaximal medical treatmentCervical sympathetic chainIschemic neurological deficitsSuperior cervical ganglionConfirmatory angiographyHorner's signIschemic deficitsLocoregional treatmentNeurological deficitsSevere vasospasmStandard therapyCerebral angiographyConsecutive patientsSympathetic chainLocoregional anesthesiaCervical ganglionInitial hemorrhageModerate symptoms
2002
Air cysts and bronchiectasis prevail in nondependent areas in severe acute respiratory distress syndrome: A computed tomographic study of ventilator-associated changes
Treggiari MM, Romand JA, Martin JB, Suter PM. Air cysts and bronchiectasis prevail in nondependent areas in severe acute respiratory distress syndrome: A computed tomographic study of ventilator-associated changes. Critical Care Medicine 2002, 30: 1747-1752. PMID: 12163787, DOI: 10.1097/00003246-200208000-00012.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAgedAPACHEBronchiectasisBronchogenic CystFemaleHumansLungLung ComplianceLung InjuryMaleMiddle AgedPneumothoraxPredictive Value of TestsPrevalenceRespiratory Distress SyndromeRetrospective StudiesSeverity of Illness IndexStatistics as TopicSurvival AnalysisSwitzerlandTime FactorsTomography, X-Ray ComputedTreatment FailureVentilators, MechanicalConceptsSevere acute respiratory distress syndromeAcute respiratory distress syndromeRespiratory distress syndromeMechanical ventilationAir cystsDistress syndromeHigh end-inspiratory pressuresVentilator-induced lung damageRetrospective observational studyPresence of pneumothoraxEnd-inspiratory pressureHigh inspiratory pressuresSeverity of changesNondependent areasLung damageInspiratory pressureMinute ventilationTomographic scanOdds ratioTomographic scanningObservational studyLung fieldsTidal volumeBronchial divisionsAbnormal parenchyma