2020
Agreement Between the Mini-Cog in the Preoperative Clinic and on the Day of Surgery and Association With Postanesthesia Care Unit Delirium: A Cohort Study of Cognitive Screening in Older Adults.
Tiwary N, Treggiari MM, Yanez ND, Kirsch JR, Tekkali P, Taylor CC, Schenning KJ. Agreement Between the Mini-Cog in the Preoperative Clinic and on the Day of Surgery and Association With Postanesthesia Care Unit Delirium: A Cohort Study of Cognitive Screening in Older Adults. Anesthesia & Analgesia 2020, 132: 1112-1119. PMID: 33002933, DOI: 10.1213/ane.0000000000005197.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnesthesia Recovery PeriodAnesthesia, GeneralCognitionCognitive DysfunctionElective Surgical ProceduresEmergence DeliriumFemaleHumansMaleMental Status and Dementia TestsPredictive Value of TestsPreoperative CareReproducibility of ResultsRisk AssessmentRisk FactorsTreatment OutcomeConceptsPostanesthesia care unitMini-Cog scorePACU deliriumDay of surgeryTimes higher oddsNormal cognitive functionCohort studyCognitive impairmentMini-CogPostoperative deliriumCognitive functionPreoperative clinicHigher oddsPatients meeting eligibility criteriaPostanesthesia Care Unit DeliriumShort Confusion Assessment MethodConfusion Assessment MethodOlder surgical patientsProspective cohort studyAnesthesiologists physical statusMultivariable logistic regressionMeeting eligibility criteriaSubjective memory impairmentOdds ratio analysisOlder patientsImplementation of the TaperGuard™ endotracheal tube in an unselected surgical population to reduce postoperative pneumonia
Martini RP, Yanez ND, Treggiari MM, Tekkali P, Soelberg C, Aziz MF. Implementation of the TaperGuard™ endotracheal tube in an unselected surgical population to reduce postoperative pneumonia. BMC Anesthesiology 2020, 20: 211. PMID: 32838740, PMCID: PMC7446207, DOI: 10.1186/s12871-020-01117-4.Peer-Reviewed Original ResearchConceptsPostoperative pneumoniaSubgroup of patientsBaseline cohortSurgical patientsIntervention cohortEndotracheal intubationOdds ratioNational Surgical Quality Improvement ProjectSurgical Quality Improvement ProjectUnselected surgical populationUnadjusted odds ratioHigh-risk populationPatient-level dataRisk of ventilatorQuality improvement projectInterrupted time series designElectronic health recordsHospital mortalityVAP bundleSurgical populationPatient characteristicsPneumonia riskHistoric cohortHospital admissionFurther risk reduction
2016
Pre-diagnostic Sleep Duration and Sleep Quality in Relation to Subsequent Cancer Survival.
Phipps AI, Bhatti P, Neuhouser ML, Chen C, Crane TE, Kroenke CH, Ochs-Balcom H, Rissling M, Snively BM, Stefanick ML, Treggiari MM, Watson NF. Pre-diagnostic Sleep Duration and Sleep Quality in Relation to Subsequent Cancer Survival. Journal Of Clinical Sleep Medicine 2016, 12: 495-503. PMID: 26612513, PMCID: PMC4795275, DOI: 10.5664/jcsm.5674.Peer-Reviewed Original ResearchConceptsWomen's Health InitiativeShort sleep durationSleep characteristicsHazard ratioCancer survivalCancer sitesSleep durationHealth initiativesPrimary invasive cancerCancer-specific survivalConfidence intervalsPoor sleep qualityFrequent snoringStudy armsCox regressionCancer outcomesInvasive cancerCommon cancerWHI participantsPhysical activitySleep qualityElevated riskCancer typesCancerMarital status
2014
Variation in Tracheal Reintubations Among Patients Undergoing Cardiac Surgery Across Washington State Hospitals
Khandelwal N, Dale CR, Benkeser DC, Joffe AM, Yanez ND, Treggiari MM. Variation in Tracheal Reintubations Among Patients Undergoing Cardiac Surgery Across Washington State Hospitals. Journal Of Cardiothoracic And Vascular Anesthesia 2014, 29: 551-559. PMID: 25802193, PMCID: PMC4427545, DOI: 10.1053/j.jvca.2014.11.009.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAirway ExtubationAirway ManagementCardiac Surgical ProceduresCohort StudiesCoronary Artery BypassCritical CareDatabases, FactualFemaleHealth SurveysHumansIntubation, IntratrachealMaleMiddle AgedRetrospective StudiesRisk FactorsSocioeconomic FactorsTreatment FailureTreatment OutcomeWashingtonConceptsIntensive care unitCardiac surgeryWashington State hospitalsNonfederal hospitalsState HospitalAcute care daysGreater hospital volumeOdds of reintubationCoronary artery bypassRetrospective cohort studyPatient-level characteristicsMultivariate logistic regressionSignificant heterogeneityValvular surgeryArtery bypassCohort studyHospital factorsHospital volumePatient characteristicsTracheal reintubationCare unitProcedure characteristicsHospital characteristicsCare daysReintubationPreoperative Consultations for Medicare Patients Undergoing Cataract Surgery
Thilen SR, Treggiari MM, Lange JM, Lowy E, Weaver EM, Wijeysundera DN. Preoperative Consultations for Medicare Patients Undergoing Cataract Surgery. JAMA Internal Medicine 2014, 174: 380-388. PMID: 24366269, PMCID: PMC4167873, DOI: 10.1001/jamainternmed.2013.13426.Peer-Reviewed Original ResearchConceptsPreoperative consultationCataract surgeryHierarchical logistic regression modelingPatients 66 yearsElective surgical proceduresLogistic regression modelingIndex surgeryCohort studyEntire cohortElective proceduresSurgical proceduresMAIN OUTCOMEMedicare beneficiariesSurgeryMedicare Part BAnesthesia providersNational random sampleUrban residenceTemporal trendsRegression modelingConsultationCohortFacility typeSuch consultationsClear guidelines
2013
Predictors of Reintubation in Critically Ill Patients
Miu T, Joffe AM, Yanez ND, Khandelwal N, Dagal AH, Deem S, Treggiari MM. Predictors of Reintubation in Critically Ill Patients. Respiratory Care 2013, 59: 178-185. PMID: 23882103, DOI: 10.4187/respcare.02527.Peer-Reviewed Original ResearchConceptsAcute Physiology Score IIDiastolic blood pressureExtubation failureScore IIBlood pressureMinute ventilationAdmission Simplified Acute Physiology Score IISimplified Acute Physiology Score IIRapid shallow breathing indexMultivariable logistic regression analysisPredictors of reintubationTertiary care centerShallow breathing indexAdditional independent predictorsBivariate logistic regression modelLogistic regression analysisLogistic regression modelsICU extubationExtubation successICU admissionBaseline characteristicsCohort studyIll patientsIndependent predictorsBreathing index
2012
Pseudomonas aeruginosa serology and risk for re-isolation in the EPIC trial
Anstead M, Heltshe SL, Khan U, Barbieri JT, Langkamp M, Döring G, Dharia S, Gibson RL, Treggiari MM, Lymp J, Rosenfeld M, Ramsey B. Pseudomonas aeruginosa serology and risk for re-isolation in the EPIC trial. Journal Of Cystic Fibrosis 2012, 12: 147-153. PMID: 22944725, PMCID: PMC3696392, DOI: 10.1016/j.jcf.2012.08.001.Peer-Reviewed Original ResearchConceptsPulmonary exacerbationsCF patientsP. aeruginosa eradicationP. aeruginosa isolationCystic fibrosis patientsEarly P. aeruginosaBaseline seropositivityEPIC trialPositive serologyAntibiotic therapyChild TrialTreatment failurePrognostic valuePseudomonas infectionWeek 10Fibrosis patientsSerologyCulture resultsPatientsClinicians' effortsExacerbationSeropositivityP. aeruginosaRiskTrialsSedation practices in a cohort of critically ill patients receiving prolonged mechanical ventilation.
Karir V, Hough CL, Daniel S, Caldwell E, Treggiari MM. Sedation practices in a cohort of critically ill patients receiving prolonged mechanical ventilation. Minerva Anestesiologica 2012, 78: 801-9. PMID: 22475804.Peer-Reviewed Original ResearchConceptsCumulative doseMorphine equivalentsIll patientsMechanical ventilationSubstance abuseDecreased opioid useLow cumulative doseRetrospective cohort studyHigh cumulative dosesMajority of patientsAmount of sedativesPatient-specific factorsUse of sedativesLess frequent useLorazepam equivalentsSedative needsAdult patientsCohort studyOpioid usePatient characteristicsOpioid analgesicsCumulative dosesEthanol abuseSedation practicesAlcohol abuse
2011
Cardioplegia and ventricular late potentials in cardiac surgical patients
Schütz N, Romand J, Yanez ND, Treggiari MM, Bendjelid K. Cardioplegia and ventricular late potentials in cardiac surgical patients. Journal Of Clinical Monitoring And Computing 2011, 25: 269. PMID: 21932050, DOI: 10.1007/s10877-011-9305-1.Peer-Reviewed Original ResearchConceptsOccurrence of LPCardiac surgical patientsCardiopulmonary bypassCardiac surgeryLate potentialsSurgical patientsAbnormal signal-averaged electrocardiogramPrevious myocardial infarctionSignal-averaged electrocardiogramConclusionsThe present studyVentricular late potentialsCPB durationMyocardial infarctionPre-post scoresMyocardial ischemiaVentricular tachycardiaElective patientsSudden deathPatientsSurgeryCardioplegiaMcNemar testPositive scoreScoresNegative scoresIntraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injury
Chaiwat O, Vavilala MS, Philip S, Malakouti A, Neff MJ, Deem S, Treggiari MM, Wang J, Lang JD. Intraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injury. Journal Of Critical Care 2011, 26: 144-151. PMID: 20869200, DOI: 10.1016/j.jcrc.2010.08.002.Peer-Reviewed Original ResearchMeSH KeywordsAcute Lung InjuryAdolescentAdultAgedAged, 80 and overAPACHECritical IllnessFemaleGuideline AdherenceHospital MortalityHumansInjury Severity ScoreIntraoperative PeriodLength of StayMaleMiddle AgedPositive-Pressure RespirationPractice Guidelines as TopicRetrospective StudiesRisk FactorsTidal VolumeYoung AdultConceptsAcute respiratory distress syndromeAcute lung injuryALI/acute respiratory distress syndromeLTV ventilationLung injuryClinical outcomesLow tidal volume ventilation strategyALI/ARDS diagnosisLow tidal volume ventilationVolume ventilation strategyRespiratory distress syndromeTidal volume ventilationARDS diagnosisHospital mortalityIntraoperative adherenceHospital lengthSecondary outcomesSurgical patientsDistress syndromeIll patientsVolume ventilationImproved oxygenationPatient outcomesRetrospective analysisMAIN OUTCOME
2009
Atrial and brain natriuretic peptide concentrations and the response to inhaled nitric oxide in patients with acute respiratory distress syndrome
Treggiari MM, Bendjelid K, Yanez ND, Heidegger CP, Suter PM, Romand JA. Atrial and brain natriuretic peptide concentrations and the response to inhaled nitric oxide in patients with acute respiratory distress syndrome. Journal Of Critical Care 2009, 25: 23-29. PMID: 19327320, DOI: 10.1016/j.jcrc.2008.10.014.Peer-Reviewed Original ResearchConceptsAcute respiratory distress syndromeAtrial natriuretic peptideBaseline atrial natriuretic peptideRespiratory distress syndromeNT-proNatriuretic peptideBNP concentrationsDistress syndromeCardiac peptidesHigh atrial natriuretic peptideBrain natriuretic peptide concentrationsB-type natriuretic peptideNitric oxideCyclic guanosine monophosphate concentrationBaseline NT-proProspective cohort studyNatriuretic peptide concentrationsSubgroup of patientsCardiac natriuretic peptidesGuanosine monophosphate concentrationCyclic guanosine monophosphateIntrapulmonary shuntCohort studyConsecutive patientsClinical benefitEarly anti-pseudomonal acquisition in young patients with cystic fibrosis: Rationale and design of the EPIC clinical trial and observational study,
Treggiari MM, Rosenfeld M, Mayer-Hamblett N, Retsch-Bogart G, Gibson RL, Williams J, Emerson J, Kronmal RA, Ramsey BW, Group E. Early anti-pseudomonal acquisition in young patients with cystic fibrosis: Rationale and design of the EPIC clinical trial and observational study,. Contemporary Clinical Trials 2009, 30: 256-268. PMID: 19470318, PMCID: PMC2783320, DOI: 10.1016/j.cct.2009.01.003.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAnti-Bacterial AgentsChildChild, PreschoolCiprofloxacinCohort StudiesCystic FibrosisDouble-Blind MethodDrug Administration ScheduleDrug Therapy, CombinationFemaleHumansInfantLongitudinal StudiesMalePseudomonas aeruginosaPseudomonas InfectionsRisk FactorsTobramycinTreatment OutcomeConceptsEarly Pa infectionYoung CF patientsRespiratory culturesRisk factorsCystic fibrosisCohort studyPA infectionClinical trialsObservational studyCF patientsEarly CF lung diseaseProgressive obstructive pulmonary diseaseProportion of patientsClinical efficacy dataObstructive pulmonary diseasePositive respiratory culturesPatients ages 1Longitudinal cohort studyCF lung diseaseChronic endobronchial infectionInfection control programPa acquisitionPA-negative patientsOral ciprofloxacinOral placebo
2006
Risk factors for reperfusion injury after lung transplantation
Cottini SR, Lerch N, de Perrot M, Treggiari MM, Spiliopoulos A, Nicod L, Ricou B. Risk factors for reperfusion injury after lung transplantation. Intensive Care Medicine 2006, 32: 557-563. PMID: 16520995, DOI: 10.1007/s00134-006-0096-7.Peer-Reviewed Original ResearchConceptsReperfusion injuryIntensive care unitPulmonary hypertensionLung transplantationHigher systolic pulmonary pressureSurgical intensive care unitDonor/recipient pairsSystolic pulmonary hypertensionSystolic pulmonary pressureAdministration of catecholaminesDifficult hemostasisSettingRetrospective studyICU mortalityPerioperative hemostasisPostoperative variablesPulmonary pressurePreoperative valuesCare unitMechanical ventilationUniversity HospitalDonor factorsEarly recognitionRisk factorsRecipient pairsRelative odds
2005
Factors Associated with Failure of Noninvasive Positive Pressure Ventilation in the Emergency Department
Merlani PG, Pasquina P, Granier JM, Treggiari M, Rutschmann O, Ricou B. Factors Associated with Failure of Noninvasive Positive Pressure Ventilation in the Emergency Department. Academic Emergency Medicine 2005, 12: 1206-1215. PMID: 16293895, DOI: 10.1197/j.aem.2005.07.018.Peer-Reviewed Original ResearchMeSH KeywordsAgedEmergency Service, HospitalFemaleHospitalizationHumansIntubation, IntratrachealMaleMultivariate AnalysisOutcome and Process Assessment, Health CarePositive-Pressure RespirationPulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk FactorsSensitivity and SpecificitySurvival AnalysisSwitzerlandTreatment FailureConceptsNoninvasive positive pressure ventilationFailure of NPPVAcute respiratory failurePositive pressure ventilationEmergency departmentRespiratory rateRespiratory failurePressure ventilationEndotracheal intubationNPPV failureGlasgow Coma Scale scoreSubsequent endotracheal intubationNegative predictive valueED admissionInstitutional protocolFactors AssociatedPatientsPredictive valueScale scoreMultivariate analysisIntubationVentilationFailureHoursDepartment
2002
Postmenopausal hormone use and skeletal fracture: does the size of the benefit decrease with increasing age?
Weiss NS, Treggiari MM. Postmenopausal hormone use and skeletal fracture: does the size of the benefit decrease with increasing age? Obstetrics And Gynecology 2002, 100: 364-8. PMID: 12151165, DOI: 10.1016/s0029-7844(02)02046-x.Peer-Reviewed Original ResearchConceptsLong-term hormone useOlder postmenopausal womenPostmenopausal womenHormone useFracture riskYounger postmenopausal womenPostmenopausal hormone useSurrogate end pointsBone mineral densityUse of hormonesHormone therapySkeletal benefitsRandomized trialsSuch therapyMineral densitySkeletal fracturesAbsolute reductionEnd pointStudy of hormonesWomenHealth careTrialsAgeTrue declineRisk