2024
Trend of Controlled Low-Density Lipoprotein Cholesterol in Older Adults With a History of Myocardial Infarction or Stroke
Park D, Jamil Y, Frampton J, Al Damluji A, Nanna M. Trend of Controlled Low-Density Lipoprotein Cholesterol in Older Adults With a History of Myocardial Infarction or Stroke. JACC Advances 2024, 3: 101091. PMID: 39099776, PMCID: PMC11294686, DOI: 10.1016/j.jacadv.2024.101091.Peer-Reviewed Original ResearchHistory of myocardial infarctionOlder adultsLow-density lipoprotein cholesterolControlled low-density lipoprotein cholesterol
2020
Performance of Guideline Recommendations for Prevention of Myocardial Infarction in Young Adults
Zeitouni M, Nanna MG, Sun JL, Chiswell K, Peterson ED, Navar AM. Performance of Guideline Recommendations for Prevention of Myocardial Infarction in Young Adults. Journal Of The American College Of Cardiology 2020, 76: 653-664. PMID: 32762899, PMCID: PMC7444655, DOI: 10.1016/j.jacc.2020.06.030.Peer-Reviewed Original ResearchConceptsLipid-lowering therapyYears of agePremature myocardial infarctionIntensive lipid-lowering therapyHigh-risk criteriaMyocardial infarctionYoung adultsYounger patientsHigh low-density lipoprotein cholesterolAHA/ACC guidelinesMajor adverse cardiovascular eventsLow-density lipoprotein cholesterolDuke University Medical CenterACC/AHAAdverse cardiovascular eventsRecurrent myocardial infarctionMost young patientsReductase inhibitor therapyFirst myocardial infarctionAmerican Heart AssociationUniversity Medical CenterOlder age groupsCause deathCholesterol guidelinesStatin candidates
2019
The Association Between Low‐Density Lipoprotein Cholesterol and Incident Atherosclerotic Cardiovascular Disease in Older Adults: Results From the National Institutes of Health Pooled Cohorts
Nanna MG, Navar AM, Wojdyla D, Peterson ED. The Association Between Low‐Density Lipoprotein Cholesterol and Incident Atherosclerotic Cardiovascular Disease in Older Adults: Results From the National Institutes of Health Pooled Cohorts. Journal Of The American Geriatrics Society 2019, 67: 2560-2567. PMID: 31411740, PMCID: PMC6898756, DOI: 10.1111/jgs.16123.Peer-Reviewed Original ResearchConceptsAtherosclerotic cardiovascular diseaseLow-density lipoprotein cholesterolIncident atherosclerotic cardiovascular diseaseRisk factorsEvent ratesLipoprotein cholesterolPooled cohortCardiovascular diseaseMultivariable-adjusted Cox proportional hazards modelsElevated low-density lipoprotein cholesterolIndividual level cohort dataCox proportional hazards modelOlder adultsASCVD event ratesCVD risk factorsCVD event ratesProspective cohort studyPresence of hyperlipidemiaProportional hazards modelNational InstituteCohort studyCVD riskMedian ageMedian LDLUnadjusted analyses