1995
PDGF and TGF-β mediate collagen production by mesangial cells exposed to advanced glycosylation end products
Throckmorton D, Brogden A, Min B, Rasmussen H, Kashgarian M. PDGF and TGF-β mediate collagen production by mesangial cells exposed to advanced glycosylation end products. Kidney International 1995, 48: 111-117. PMID: 7564067, DOI: 10.1038/ki.1995.274.Peer-Reviewed Original Research
1992
The pathobiology of the mesangium
Kashgarian M, Sterzel R. The pathobiology of the mesangium. Kidney International 1992, 41: 524-529. PMID: 1573822, DOI: 10.1038/ki.1992.74.Peer-Reviewed Original ResearchConceptsGlomerular diseaseAdvanced glomerular lesionsProgressive glomerular diseaseGlomerular capillary tuftDiabetic nephropathyIgA nephropathyMesangiocapillary glomerulonephritisGlomerular lesionsHistologic abnormalitiesGlomerular morphologySegmental glomerulosclerosisChronic diseasesSclerotic responseProliferative responseEpithelial cell layerMesangial matrixMesangial cellsCapillary tuftMesangiumDiseaseNephropathyCell layerObvious involvementPathobiologyMammalian kidney
1989
Formation of extracellular matrix by cultured rat mesangial cells.
Ishimura E, Sterzel R, Budde K, Kashgarian M. Formation of extracellular matrix by cultured rat mesangial cells. American Journal Of Pathology 1989, 134: 843-55. PMID: 2650558, PMCID: PMC1879799.Peer-Reviewed Original Research
1986
Mesangial cell hillocks. Nodular foci of exaggerated growth of cells and matrix in prolonged culture.
Sterzel R, Lovett D, Foellmer H, Perfetto M, Biemesderfer D, Kashgarian M. Mesangial cell hillocks. Nodular foci of exaggerated growth of cells and matrix in prolonged culture. American Journal Of Pathology 1986, 125: 130-40. PMID: 3535527, PMCID: PMC1888434.Peer-Reviewed Original ResearchConceptsMesangial cellsNecrotic cell debrisCollagen type IMesangial matrix productionCultured mesangial cellsGlomerular mesangial cellsIsolated rat glomeruliType ISpecific rabbit polyclonal antibodiesNodular fociFetal calf serumDiseased glomeruliMC proliferationRabbit polyclonal antibodyStellate cellsNormal glomeruliMatrix proteinsInterstitial collagen types ICell debrisImmunocytochemical studyNodular accumulationMetabolic stimuliIntracellular fibrilsRat glomeruliGlomeruli