1998
Antibodies against mesangial cells and their secretory products in chronic renal allograft rejection in the rat.
Paul L, Muralidharan J, Muzaffar S, Manting E, Valentin J, de Heer E, Kashgarian M. Antibodies against mesangial cells and their secretory products in chronic renal allograft rejection in the rat. American Journal Of Pathology 1998, 152: 1209-23. PMID: 9588890, PMCID: PMC1858589.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAutoantibodiesAutoantigensBasement MembraneBiglycanBlotting, WesternCells, CulturedChronic DiseaseDecorinEndothelium, VascularExtracellular Matrix ProteinsFlow CytometryFluorescent Antibody Technique, IndirectGlomerular MesangiumGraft RejectionKidney TransplantationMaleProteoglycansRatsRats, Inbred F344Rats, Inbred LewTransplantation, HomologousConceptsMesangial cell culture supernatantsChronic renal allograft rejectionRenal allograft rejectionMesangial cellsChronic rejectionAllograft rejectionCell culture supernatantsChronic renal transplant rejectionFlow cytometryWestern blotEndothelial cellsGlomerular basement membrane antigenPost-transplant seraRenal transplant rejectionCell-mediated immunityPost-immunization seraPresence of antibodiesMesangial cell surfaceStrong autoantibody responseCulture supernatantsCultured mesangial cellsIndirect immunofluorescent studiesBasement membrane antigensIndirect immunofluorescent stainingTissue repair process
1993
Effect of transforming growth factor-β on extracellular matrix productionby cultured rat mesangial cells
ISHIMURA E, MORII H, STERZEL R, KASHGARIAN M. Effect of transforming growth factor-β on extracellular matrix productionby cultured rat mesangial cells. 日本腎臓学会誌 1993, 35: 311-320. PMID: 8341006, DOI: 10.14842/jpnjnephrol1959.35.311.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCells, CulturedCollagenExtracellular MatrixExtracellular Matrix ProteinsGene ExpressionGlomerular MesangiumLamininMaleRatsRats, Sprague-DawleyTransforming Growth Factor betaConceptsNorthern blottingCultured rat mesangial cellsRat mesangial cellsCollagen IExtracellular matrix constituentsMesangial cellsGrowth factorEnzyme-linked immunoadsorbent assayGene expressionProtein productionSingle growth factorECM constituentsProtein synthesisGenetic expressionMatrix componentsLamininExpressionGlomerular remodelingECM accumulationTGF-beta administrationBlottingMRNA expressionMatrix constituentsCellsGlomerular injury
1992
Extracellular matrix protein: gene expression and synthesis in cultured rat mesangial cells
ISHIMURA E, STERZEL R, MORII H, KASHGARIAN M. Extracellular matrix protein: gene expression and synthesis in cultured rat mesangial cells. 日本腎臓学会誌 1992, 34: 9-17. PMID: 1593802, DOI: 10.14842/jpnjnephrol1959.34.9.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlotting, NorthernEnzyme-Linked Immunosorbent AssayExtracellular Matrix ProteinsGene ExpressionGlomerular MesangiumMaleRatsRats, Inbred StrainsRNA, MessengerConceptsGene expressionProtein synthesisExtracellular matrixNorthern blottingBasement membrane matrix componentsFetal calf serumCollagen IMesangial cellsMRNA expressionDNA amountSynthesis of ECMCellular confluenceECM productionCultured rat mesangial cellsMatrix componentsRat mesangial cellsExpressionLamininBlottingCellsCalf serumImmunocytochemical studyPrevious immunocytochemical studiesCIIIMRNA