1982
Accelerated recovery of single nephron function by the postischemic infusion of ATP-MgCl2
Gaudio K, Taylor M, Chaudry I, Kashgarian M, Siegel N. Accelerated recovery of single nephron function by the postischemic infusion of ATP-MgCl2. Kidney International 1982, 22: 13-20. PMID: 7120752, DOI: 10.1038/ki.1982.126.Peer-Reviewed Original ResearchConceptsClearance of inulinSingle nephron functionATP-MgCl2Proximal tubular pressureNephron functionTubular pressureBeneficial effectsRenal artery ischemiaSaline-treated animalsSaline-treated ratsCourse of recoveryGroups of animalsPostischemic administrationArtery ischemiaPattern of recoveryCIN 1Postischemic infusionInitial insultInulin clearanceInitial improvementControl animalsMost epithelial cellsEnhanced recoveryWhole kidneyTubular fluid
1978
Effects of potassium depletion on renal tubular chloride transport in the rat
Luke R, Wright F, Fowler N, Kashgarian M, Giebisch G. Effects of potassium depletion on renal tubular chloride transport in the rat. Kidney International 1978, 14: 414-427. PMID: 35645, DOI: 10.1038/ki.1978.146.Peer-Reviewed Original ResearchConceptsEarly distal tubuleLoop of HenleDistal tubulesKD groupChloride reabsorptionProximal tubulesPotassium depletionAbsolute chloride reabsorptionAdministration of DOCASingle nephron GFRRenal tubular reabsorptionPotassium-depleted ratsLate distal tubuleEffects of KDNephron GFRTubular reabsorptionChloride intakeFractional reabsorptionClearance studiesDay 2Fractional deliveryMuscle potassiumWhole kidneyDay 9Rats