1986
No aggravation of the course of experimental glomerulonephritis in spontaneously hypertensive rats.
Stein H, Sterzel R, Hunt J, Pabst R, Kashgarian M. No aggravation of the course of experimental glomerulonephritis in spontaneously hypertensive rats. American Journal Of Pathology 1986, 122: 520-30. PMID: 3513602, PMCID: PMC1888211.Peer-Reviewed Original ResearchMeSH KeywordsAlbuminuriaAnimalsAntibodies, Anti-IdiotypicAntibody FormationAutoradiographyBlood PressureFluorescent Antibody TechniqueGlomerulonephritisHistocytochemistryHypertensionImmune System DiseasesImmunoglobulin GKidneyMaleMicroscopy, ElectronRabbitsRatsRats, Inbred SHRRats, Inbred WKYThymidineConceptsWistar-Kyoto controlsBlood pressureGBM nephritisRenal injurySystemic hypertensionHypertensive ratsNormotensive Wistar-Kyoto (WKY) controlsAntiglomerular basement membrane nephritisUrinary albumin excretionSystolic blood pressureIgG antibody productionHumoral antibody responseNonspecific esteraseLight microscopyAlbumin excretionAutoregulatory capacityControl SHRMild hypertensionMorphologic injuryCreatinine clearanceGlomerular alterationsSerum creatinineNSE stainingHumoral responseAntibody response
1983
Role of angiotensin II-induced renal functional changes in mesangial deposition of exogenous ferritin in rats.
Stein H, Feddergreen W, Kashgarian M, Sterzel R. Role of angiotensin II-induced renal functional changes in mesangial deposition of exogenous ferritin in rats. Laboratory Investigation 1983, 49: 270-80. PMID: 6350702.Peer-Reviewed Original ResearchConceptsBlood pressureFiltration fractionMesangial localizationAngiotensin IIFunctional changesAcute angiotensin IIAminohippuric acid clearanceRenal functional changesSystolic blood pressureExcretion of albuminSingle intravenous doseGlomerular capillary permeabilityGroups of ratsInjection of ferritinPressor doseAcid clearanceIntravenous doseMesangial depositionMesangial accumulationFerritin concentrationInulin clearanceTreatment periodRenal tissueSerial measurementsFerritin deposition