1994
The benefit of early treatment with immunosuppressive agents in lupus nephritis.
Esdaile J, Joseph L, MacKenzie T, Kashgarian M, Hayslett J. The benefit of early treatment with immunosuppressive agents in lupus nephritis. The Journal Of Rheumatology 1994, 21: 2046-51. PMID: 7869308.Peer-Reviewed Original ResearchConceptsHour urinary protein excretionUrinary protein excretionLead-time biasRenal biopsyLupus nephritisRenal insufficiencyRenal involvementSerum creatinineProtein excretionImmunosuppressive agentsEarly treatmentHigh-dose prednisoneLupus renal involvementSubsequent renal insufficiencyTime biasFirst renal biopsySelection biasDose prednisoneTubulointerstitial indexRenal diseaseLongterm prognosisImmunosuppressive drugsEffect of durationBiopsySignificant associationThe Time‐Dependence of Long‐Term Prediction in Lupus Nephritis
Esdaile J, Abrahamowicz M, Mackenzie T, Hayslett J, Kashgarian M. The Time‐Dependence of Long‐Term Prediction in Lupus Nephritis. Arthritis & Rheumatism 1994, 37: 359-368. PMID: 8129791, DOI: 10.1002/art.1780370309.Peer-Reviewed Original ResearchConceptsDisease activity measuresLupus nephritisRenal failureActivity measuresLupus nephritis patientsRenal failure outcomeObservation periodCox model analysisLong-term outcomesMean followup timeGood prognostic markerNonrenal outcomesTubulointerstitial indexChronicity indexNephritis patientsRenal outcomesExtended observation periodRenal involvementComorbid diseasesPrognostic factorsRenal functionDevelopment of diseaseRenal biopsyFollowup timeLaboratory predictors
1981
Wegener's Granulomatosis — Clinical-Pathologic Correlations and Long-Term Course
Appel G, Gee B, Kashgarian M, Hayslett J. Wegener's Granulomatosis — Clinical-Pathologic Correlations and Long-Term Course. American Journal Of Kidney Diseases 1981, 1: 27-37. PMID: 7332000, DOI: 10.1016/s0272-6386(81)80008-x.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseModern immunosuppressive therapyLong-term courseClinical-pathologic entityLong-term reportsImmunosuppressive therapyRenal involvementRenal manifestationsSerum creatinineWegener's granulomatosisRenal diseaseEventual prognosisSingle institutionLight microscopic morphologyPathologic correlationMedical CenterRenal tissueDisease processRespiratory tissuesSpecific diagnosisPotential diagnosisPatientsDiagnosisGranulomatosisBiopsy