1994
The benefit of early treatment with immunosuppressive agents in lupus nephritis.
Esdaile J, Joseph L, MacKenzie T, Kashgarian M, Hayslett J. The benefit of early treatment with immunosuppressive agents in lupus nephritis. The Journal Of Rheumatology 1994, 21: 2046-51. PMID: 7869308.Peer-Reviewed Original ResearchConceptsHour urinary protein excretionUrinary protein excretionLead-time biasRenal biopsyLupus nephritisRenal insufficiencyRenal involvementSerum creatinineProtein excretionImmunosuppressive agentsEarly treatmentHigh-dose prednisoneLupus renal involvementSubsequent renal insufficiencyTime biasFirst renal biopsySelection biasDose prednisoneTubulointerstitial indexRenal diseaseLongterm prognosisImmunosuppressive drugsEffect of durationBiopsySignificant association
1977
SEQUENTIAL HISTOLOGIC CHANGES IN UNTREATED MESANGIALCAPILLARY GLOMERULONEPHRITIS (MCGN)
Siegel N, Kashgarian M. SEQUENTIAL HISTOLOGIC CHANGES IN UNTREATED MESANGIALCAPILLARY GLOMERULONEPHRITIS (MCGN). Pediatric Research 1977, 11: 557-557. DOI: 10.1203/00006450-197704000-01126.Peer-Reviewed Original ResearchInterstitial fibrosisMesangial sclerosisSubendothelial depositsSecond renal biopsyDiffuse mesangial proliferationHistologic improvementSteroid therapyImmunosuppressive agentsRenal biopsyInitial diagnosisMesangial proliferationPatientsSubepithelial depositsSequential histologicSclerosisBasement membraneFibrosisRecent dataSignificant changesProliferationProgressive changesGlomerulonephritisBiopsyHistologicTherapy