Role of angiotensin II-induced renal functional changes in mesangial deposition of exogenous ferritin in rats.
Stein H, Feddergreen W, Kashgarian M, Sterzel R. Role of angiotensin II-induced renal functional changes in mesangial deposition of exogenous ferritin in rats. Laboratory Investigation 1983, 49: 270-80. PMID: 6350702.Peer-Reviewed Original ResearchConceptsBlood pressureFiltration fractionMesangial localizationAngiotensin IIFunctional changesAcute angiotensin IIAminohippuric acid clearanceRenal functional changesSystolic blood pressureExcretion of albuminSingle intravenous doseGlomerular capillary permeabilityGroups of ratsInjection of ferritinPressor doseAcid clearanceIntravenous doseMesangial depositionMesangial accumulationFerritin concentrationInulin clearanceTreatment periodRenal tissueSerial measurementsFerritin depositionAccelerated cellular recovery after an ischemic renal injury.
Gaudio K, Ardito T, Reilly H, Kashgarian M, Siegel N. Accelerated cellular recovery after an ischemic renal injury. American Journal Of Pathology 1983, 112: 338-46. PMID: 6604459, PMCID: PMC1916386.Peer-Reviewed Original ResearchConceptsProximal tubular pressureCellular morphologic featuresRenal ischemiaATP-MgCl2Back leakTubular integrityMorphologic featuresCellular damageIschemic cellular damageProgressive ischemic injurySevere ischemic damageIschemic renal injurySaline-treated ratsGroups of ratsEarly regenerative changesRenal injuryIschemic damageIschemic injuryIschemic alterationsNormal salineRegenerative changesSaline ratsEnhances recoverySalutary effectsHistomorphometric analysis