2021
Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery (ERAS) Society Recommendations: Part 1—Preoperative: Diagnosis, Rapid Assessment and Optimization
Peden C, Aggarwal G, Aitken R, Anderson I, Foss N, Cooper Z, Dhesi J, French W, Grant M, Hammarqvist F, Hare S, Havens J, Holena D, Hübner M, Kim J, Lees N, Ljungqvist O, Lobo D, Mohseni S, Ordoñez C, Quiney N, Urman R, Wick E, Wu C, Young-Fadok T, Scott M. Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery (ERAS) Society Recommendations: Part 1—Preoperative: Diagnosis, Rapid Assessment and Optimization. World Journal Of Surgery 2021, 45: 1272-1290. PMID: 33677649, PMCID: PMC8026421, DOI: 10.1007/s00268-021-05994-9.Peer-Reviewed Original ResearchConceptsEmergency laparotomyERAS approachEmergency general surgical patientsFirst consensus guidelinesSurgery (ERAS) Society RecommendationsEmergency general surgeryGeneral surgical patientsGrading of RecommendationsHigh-risk patientsLength of stayElective surgical proceduresLarge cohort studyBest available evidenceMEDLINE database searchNon-emergency patientsEnglish-language publicationsERAS elementsCohort studyInitial managementSurgery protocolSurgical patientsPerioperative carePhysiological derangementsPreoperative carePostoperative management
2020
Opioid-Sparing Cardiac Anesthesia: Secondary Analysis of an Enhanced Recovery Program for Cardiac Surgery.
Grant M, Isada T, Ruzankin P, Gottschalk A, Whitman G, Lawton J, Dodd-O J, Barodka V. Opioid-Sparing Cardiac Anesthesia: Secondary Analysis of an Enhanced Recovery Program for Cardiac Surgery. Anesthesia & Analgesia 2020, 131: 1852-1861. PMID: 32889848, DOI: 10.1213/ane.0000000000005152.Peer-Reviewed Original ResearchConceptsIntraoperative opioid administrationEnhanced recovery programmeOpioid administrationCardiac surgeryNonopioid interventionsPostoperative outcomesNumber of interventionsOpioid patientsSecondary analysisSerratus anterior plane blockMorphine sulfate equivalentsOpioid-sparing strategiesPostoperative pain scoresFuture prospective studiesLength of stayLinear mixed-effects regression modelsMixed-effects regression modelsIntraoperative dexmedetomidineLower opioidPreoperative gabapentinMultimodal analgesiaPain scoresPostoperative complicationsOpioid usePlane blockCardiac Enhanced Recovery After Surgery: A Guide to Team Building and Successful Implementation
Salenger R, Morton-Bailey V, Grant M, Gregory A, Williams J, Engelman D. Cardiac Enhanced Recovery After Surgery: A Guide to Team Building and Successful Implementation. Seminars In Thoracic And Cardiovascular Surgery 2020, 32: 187-196. PMID: 32120008, DOI: 10.1053/j.semtcvs.2020.02.029.Peer-Reviewed Original ResearchMeSH KeywordsCardiac Surgical ProceduresClinical CompetenceCooperative BehaviorDelivery of Health Care, IntegratedEnhanced Recovery After SurgeryHumansInterdisciplinary CommunicationOrganizational InnovationPatient Care TeamPatient-Centered CareProgram DevelopmentRecovery of FunctionTime FactorsTreatment OutcomeConceptsEnhanced recoveryCardiac programApplication of ERASEffect of ERASNormal functional statusLength of stayCompleteness of recoveryPostoperative complicationsColorectal surgeryERAS programCardiac surgeryPerioperative careFunctional statusSurgeryPatientsPhysiologic stressSurgical subspecialtiesERASStaff satisfactionMultiple studiesPatient-centered systemCareComplicationsStay
2019
Opioid tolerance impacts compliance with enhanced recovery pathway after major abdominal surgery
Owodunni O, Zaman M, Ighani M, Grant M, Bettick D, Sateri S, Magnuson T, Gearhart S. Opioid tolerance impacts compliance with enhanced recovery pathway after major abdominal surgery. Surgery 2019, 166: 1055-1060. PMID: 31526584, DOI: 10.1016/j.surg.2019.08.001.Peer-Reviewed Original ResearchConceptsEnhanced recovery pathwayMajor abdominal surgeryOpioid-tolerant patientsOpioid toleranceAbdominal surgeryLength of stayTolerant patientsRecovery pathwaysPostoperative outcomesMajor complicationsPathway complianceChallenging patient cohortNon-tolerant patientsPoor postoperative outcomesOperative Severity ScoreEnUmeration of MortalityRisk-adjusted analysisPrescribed opioid medicationsOutcomes of interestEvidence-based interventionsColorectal PhysiologicalOral morphineOpioid medicationsEmergency surgeryReadmission ratesImpact of Preoperative Erythropoietin on Allogeneic Blood Transfusions in Surgical Patients
Cho B, Serini J, Zorrilla-Vaca A, Scott M, Gehrie E, Frank S, Grant M. Impact of Preoperative Erythropoietin on Allogeneic Blood Transfusions in Surgical Patients. Anesthesia & Analgesia 2019, Publish Ahead of Print: &na;. PMID: 30649068, DOI: 10.1213/ane.0000000000004005.Peer-Reviewed Original ResearchConceptsRed blood cell transfusionAllogeneic blood transfusionBlood cell transfusionAllogeneic red blood cell transfusionPerioperative allogeneic blood transfusionBlood transfusionPreoperative erythropoietinCell transfusionThromboembolic eventsPatient blood management programPreoperative erythropoietin administrationSubset of patientsBlood management programPerioperative hemoglobin levelsErythropoietic stimulating agentsLength of stayErythropoietin useSecondary outcomesSurgical patientsThromboembolic complicationsBlood lossPrimary outcomeHemoglobin levelsRisk of exposureInpatient hospitalizationAnesthesia for Spine Surgery
Zorrilla-Vaca A, Grant M, Mirski M. Anesthesia for Spine Surgery. 2019, 189-200. DOI: 10.1007/978-981-13-3387-3_14.Peer-Reviewed Original ResearchSpine surgeryMultimodal analgesic strategyIntraoperative blood lossLumbar spine surgeryLength of stayManagement of anesthesiaPatient-focused approachAnalgesic strategiesHospital stayPostoperative complicationsPostoperative nauseaPostoperative painPostoperative outcomesAnesthetic managementBlood lossAnesthetic techniqueGeneral anesthesiaIntraoperative stabilityPerioperative assessmentOptimal anesthesiaRegional anesthesiaRegional techniquesSurgery programSurgeryAnesthesiaThe Impact of Anesthesia-Influenced Process Measure Compliance on Length of Stay
Grant M, Pio Roda C, Canner J, Sommer P, Galante D, Hobson D, Gearhart S, Wu C, Wick E. The Impact of Anesthesia-Influenced Process Measure Compliance on Length of Stay. Anesthesia & Analgesia 2019, 128: 68-74. PMID: 29782405, DOI: 10.1213/ane.0000000000003458.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnesthesiaAnesthesiologistsColonDigestive System Surgical ProceduresFemaleGuideline AdherenceHumansInterdisciplinary CommunicationLength of StayMaleMiddle AgedOutcome and Process Assessment, Health CarePatient Care TeamPerioperative CarePractice Guidelines as TopicPractice Patterns, Physicians'Program EvaluationQuality ImprovementQuality Indicators, Health CareRecovery of FunctionRectumTime FactorsTreatment OutcomeConceptsProcess measure complianceMeasure complianceProcess measuresAcute pain servicePain medication useLength of staySpecific process measuresImpact of complianceBreakthrough painHospital lengthPain serviceSurgery cohortERAS programSurgical encountersConsecutive patientsMedication usePerioperative careShorter LOSAnesthesia protocolImproved outcomesMultivariable regressionSurgery programEnhanced recoveryPatientsLOS
2017
Dedicated Operating Room Teams and Clinical Outcomes in an Enhanced Recovery after Surgery Pathway for Colorectal Surgery
Grant MC, Hanna A, Benson A, Hobson D, Wu CL, Yuan CT, Rosen M, Wick EC. Dedicated Operating Room Teams and Clinical Outcomes in an Enhanced Recovery after Surgery Pathway for Colorectal Surgery. Journal Of The American College Of Surgeons 2017, 226: 267-276. PMID: 29274837, DOI: 10.1016/j.jamcollsurg.2017.12.010.Peer-Reviewed Original ResearchConceptsClinical outcomesProcess measure complianceEnhanced recoveryMeasure complianceOperating room teamSurgery programAnesthesia providersSurgical site infectionLength of stayHigh complianceColorectal surgeryERAS implementationERAS programSite infectionPerioperative careSurgery pathwayProvider teamProtocol elementsNurse anesthetistsIndividual providersDedicated teamOutcomesSignificant increaseSignificant reductionAnesthesiologistsOptimizing an Enhanced Recovery Pathway Program: Development of a Postimplementation Audit Strategy
Grant M, Galante D, Hobson D, Lavezza A, Friedman M, Wu C, Wick E. Optimizing an Enhanced Recovery Pathway Program: Development of a Postimplementation Audit Strategy. The Joint Commission Journal On Quality And Patient Safety 2017, 43: 524-533. PMID: 28942777, DOI: 10.1016/j.jcjq.2017.02.011.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersClinical ProtocolsDigestive System Surgical ProceduresElectronic Health RecordsFemaleGroup ProcessesHumansLength of StayMaleMiddle AgedOrganizational CulturePatient Care BundlesPatient Care TeamPerioperative CarePostoperative ComplicationsQuality Indicators, Health CareRetrospective StudiesSafety ManagementConceptsLength of stayOverall LOSAverage LOSProcess measuresThree-month followProcess measure complianceAcademic medical centerSystem-level interventionsSignificant reductionElectronic health recordsColorectal surgeryConsecutive patientsPathway implementationEarly mobilityMeasure complianceMedical CenterPreventable harmOne-year periodPatientsRecovery pathwaysHealth recordsSystem-level changesSurgeryComplianceSame procedureIs enhanced recovery enough for reducing 30-d readmissions after surgery?
Fabrizio A, Grant M, Siddiqui Z, Alimi Y, Gearhart S, Wu C, Efron J, Wick E. Is enhanced recovery enough for reducing 30-d readmissions after surgery? Journal Of Surgical Research 2017, 217: 45-53. PMID: 28602223, DOI: 10.1016/j.jss.2017.04.007.Peer-Reviewed Original ResearchConceptsEnhanced recovery pathwaySurgical site infectionSite infectionSingle tertiary care centerPostoperative surgical site infectionIndex hospitalization lengthTertiary care centerEnhanced recovery programmeLength of stayTransitions of carePatient care experiencesColorectal surgeryReadmission ratesReduced readmissionsHospitalization lengthRetrospective studyCare transitionsCare centerPatient outcomesReadmissionSymptom monitoringSimilar cohortEnhanced recoveryHome transfersCare experiencesPreserved Analgesia With Reduction in Opioids Through the Use of an Acute Pain Protocol in Enhanced Recovery After Surgery for Open Hepatectomy
Grant M, Sommer P, He C, Li S, Page A, Stone A, Hobson D, Wick E, Wu C. Preserved Analgesia With Reduction in Opioids Through the Use of an Acute Pain Protocol in Enhanced Recovery After Surgery for Open Hepatectomy. Regional Anesthesia & Pain Medicine 2017, 42: 451-457. PMID: 28525409, DOI: 10.1097/aap.0000000000000615.Peer-Reviewed Original ResearchConceptsOpen hepatectomyPain scoresERAS pathwayERAS protocolEnd pointPain controlSelf-reported pain scoresAcute pain protocolsAverage pain scoreLess morphine equivalentsMorphine equivalent requirementsOpioid-based medicationsProvision of fluidsLiver resection surgeryOptimal pain controlUse of epiduralsLength of stayHigh-risk procedurePostoperative end pointsERAS settingMorphine equivalentsNonepidural groupOpioid requirementsPerioperative opioidsEpidural analgesiaImpact of Enhanced Recovery After Surgery and Fast Track Surgery Pathways on Healthcare-associated Infections
Grant M, Yang D, Wu C, Makary M, Wick E. Impact of Enhanced Recovery After Surgery and Fast Track Surgery Pathways on Healthcare-associated Infections. Annals Of Surgery 2017, 265: 68-79. PMID: 28009729, DOI: 10.1097/sla.0000000000001703.Peer-Reviewed Original ResearchConceptsHealthcare-associated infectionsSurgical site infectionUrinary tract infectionLung infectionFTS protocolFast-track surgery pathwaysFast-track surgery protocolMajor healthcare-associated infectionPostoperative lung infectionLength of staySignificant reductionPostoperative incidenceHospital lengthColorectal surgerySurgery protocolTract infectionsPerioperative carePrimary outcomeSite infectionRandomized trialsSurgery pathwayPelvic surgerySubgroup analysisSurgical careHigh risk