2014
Trafficking to the Apical and Basolateral Membranes in Polarized Epithelial Cells
Stoops EH, Caplan MJ. Trafficking to the Apical and Basolateral Membranes in Polarized Epithelial Cells. Journal Of The American Society Of Nephrology 2014, 25: 1375-1386. PMID: 24652803, PMCID: PMC4073435, DOI: 10.1681/asn.2013080883.Peer-Reviewed Original ResearchConceptsTrafficking routesCell type-specific variationsDistinct protein compositionTrans-Golgi networkPolarized epithelial cellsCellular trafficking pathwaysEpithelial cellsBasolateral membraneType-specific variationsBasolateral proteinsTrafficking pathwaysRecycling endosomesRenal epithelial cellsDifferent developmental statesCarrier vesiclesProtein distributionProtein compositionTransport functionProteinK-ATPaseCurrent understandingCellsPathwayRemarkable capacityDevelopmental state
1991
Chapter 2 Biogenesis and Sorting of Plasma Membrane Proteins
Caplan M. Chapter 2 Biogenesis and Sorting of Plasma Membrane Proteins. Current Topics In Membranes 1991, 39: 37-86. PMCID: PMC7128438, DOI: 10.1016/s0070-2161(08)60800-x.Peer-Reviewed Original ResearchPlasma membrane proteinsPlasma membraneMembrane proteinsCell typesCell surfacePolarized epithelial cellsApical plasma membraneDistribution of polypeptidesExpression of genesCell surface membraneTransducer proteinsAnchor cellCell biologyProtein compositionProteinMost cellsBiogenesisFascinating questionsPlasmalemmal receptorsOrganellesEpithelial cellsSurface membranePolypeptideMembranePlasmalemma
1987
Dependence on pH of polarized sorting of secreted proteins
Caplan M, Stow J, Newman A, Madri J, Anderson H, Farquhar M, Palade G, Jamieson J. Dependence on pH of polarized sorting of secreted proteins. Nature 1987, 329: 632-635. PMID: 2821405, DOI: 10.1038/329632a0.Peer-Reviewed Original ResearchConceptsSecretory proteinsMDCK cellsDifferent protein compositionsBasolateral cell surfacePolarized sortingMembrane proteinsBasolateral domainDefault pathwayPlasma membraneAcidic intracellular compartmentsIntracellular compartmentsProtein compositionMembrane componentsCell surfaceBasement membrane componentsProteinSecrete lamininDistinct setsRenal tubule cellsEpithelial cellsActive sortingBasolateral compartmentCellsSecretory productsSpecific regions