2015
Emergency Department–Initiated Buprenorphine/Naloxone Treatment for Opioid Dependence: A Randomized Clinical Trial
D’Onofrio G, O’Connor P, Pantalon MV, Chawarski MC, Busch SH, Owens PH, Bernstein SL, Fiellin DA. Emergency Department–Initiated Buprenorphine/Naloxone Treatment for Opioid Dependence: A Randomized Clinical Trial. JAMA 2015, 313: 1636-1644. PMID: 25919527, PMCID: PMC4527523, DOI: 10.1001/jama.2015.3474.Peer-Reviewed Original ResearchConceptsBrief intervention groupOpioid-dependent patientsIllicit opioid useAddiction treatment servicesPercent of patientsBuprenorphine groupEmergency departmentIntervention groupReferral groupOpioid useTreatment servicesBrief interventionOpioid dependenceClinical trialsHIV riskUrban teaching hospital emergency departmentBuprenorphine/naloxone treatmentHuman immunodeficiency virus (HIV) riskTeaching hospital emergency departmentAddiction treatmentBuprenorphine treatment groupUrine samplesBuprenorphine/naloxoneRandomized clinical trialsCommunity-based treatment services
2006
Coronary stenting is safe and effective in a high-risk octogenarian patient cohort.
Baklanov DV, Marcu CB, Juhasz DF, Caracciolo EA, Chawarski MC, Donohue TJ. Coronary stenting is safe and effective in a high-risk octogenarian patient cohort. Connecticut Medicine 2006, 70: 15-9. PMID: 16479871.Peer-Reviewed Original ResearchConceptsTarget vessel revascularization rateCoronary stentingProcedural successNew York Heart Association class IIIHigh procedural success rateSerial cardiac enzymesVessel revascularization ratePercent of patientsTIMI 3 flowAcute coronary syndromeMajor cardiac eventsProcedural success rateLow complication rateCoronary heart diseaseCommunity teaching hospitalHigh-risk populationLong-term resultsCoronary stent proceduresAngiographic profileCoronary syndromeIndex hospitalizationRevascularization ratesCardiac eventsComplication rateResidual stenosis