2023
Biomolecular Condensation of SH2 Domain-Containing Proteins on Membranes
Zeng L, Su X. Biomolecular Condensation of SH2 Domain-Containing Proteins on Membranes. Methods In Molecular Biology 2023, 2705: 371-379. PMID: 37668985, DOI: 10.1007/978-1-0716-3393-9_20.Peer-Reviewed Original ResearchConceptsSH2 domainSH2 domain-containing proteinsDomain-containing proteinsT cell receptorReceptors/adaptorsReceptor pathwayContext of membraneEndomembrane systemMembrane receptor pathwaysSignal transductionBiomolecular condensationSpecific tyrosinePlasma membraneReconstitution systemGolgi apparatusEndoplasmic reticulumLiquid-liquid phase separationMultivalent interactionsCondensate formationProteinMembranePathwayPhosphotyrosineAssaysTransduction
2017
Structural basis of host recognition and biofilm formation by Salmonella Saf pili
Zeng L, Zhang L, Wang P, Meng G. Structural basis of host recognition and biofilm formation by Salmonella Saf pili. ELife 2017, 6: e28619. PMID: 29125121, PMCID: PMC5700814, DOI: 10.7554/elife.28619.Peer-Reviewed Original ResearchConceptsHost recognitionBiofilm formationNovel functionStructure-based mutantsSelf-association activityFunctional characterizationBiofilm formation assaysStructural basisBacterial aggregationFormation assaysCell aggregationPiliAdherence assaysColonizationSAXS characterizationAssaysMutantsSAFABacterial infectionsSAFDOligomerizationCrystal structureAggregationMechanismFormation