2020
Neuropsychiatric Aspects of Epilepsy
Tolchin B, Hirsch LJ, LaFrance WC. Neuropsychiatric Aspects of Epilepsy. Psychiatric Clinics Of North America 2020, 43: 275-290. PMID: 32439022, DOI: 10.1016/j.psc.2020.02.002.Peer-Reviewed Original ResearchMeSH KeywordsAnxietyCognitive DysfunctionComorbidityDepressionEpilepsyHumansPsychotic DisordersQuality of LifeConceptsNeuropsychiatric disordersNeuropsychiatric aspectsCertain neuropsychiatric disordersAntiseizure medicationsClinical outcomesTherapeutic optionsEpidemiologic studiesEpilepsyMultidisciplinary teamNeuropsychiatric impactDisordersBidirectional relationshipTreatmentClose collaborationComorbiditiesMedicationsPathophysiologySocial factorsDiagnosis
2017
Time‐dependent risk of seizures in critically ill patients on continuous electroencephalogram
Struck AF, Osman G, Rampal N, Biswal S, Legros B, Hirsch LJ, Westover MB, Gaspard N. Time‐dependent risk of seizures in critically ill patients on continuous electroencephalogram. Annals Of Neurology 2017, 82: 177-185. PMID: 28681492, PMCID: PMC5842678, DOI: 10.1002/ana.24985.Peer-Reviewed Original ResearchConceptsEpileptiform EEG abnormalitiesClinical factorsIll patientsEpileptiform findingsRisk factorsEEG abnormalitiesEEG risk factorsClinical risk factorsRisk of seizuresHistory of seizuresPresence of comaDuration of monitoringGreater predictive valueTime-dependent riskAnn NeurolSeizure incidenceAcute illnessPrior seizuresClinical variablesEEG findingsProspective dataSeizure riskBaseline riskMultistate survival modelsPredictive value
2007
Generalized convulsive status epilepticus after nontraumatic subarachnoid hemorrhage: the nationwide inpatient sample.
Claassen J, Bateman BT, Willey JZ, Inati S, Hirsch LJ, Mayer SA, Sacco RL, Schumacher HC. Generalized convulsive status epilepticus after nontraumatic subarachnoid hemorrhage: the nationwide inpatient sample. Neurosurgery 2007, 61: 60-4; discussion 64-5. PMID: 17621019, DOI: 10.1227/01.neu.0000279724.05898.e7.Peer-Reviewed Original ResearchConceptsNontraumatic subarachnoid hemorrhageConvulsive status epilepticusNationwide Inpatient SampleSubarachnoid hemorrhageRenal diseaseStatus epilepticusInpatient SampleNonfederal United States hospitalsGeneralized convulsive status epilepticusDatabase of admissionsDuration of hospitalizationMultivariate logistic regressionUnited States hospitalsHospital mortalityHospital stayAdult patientsYounger patientsIndependent predictorsPatient mortalityEmergency departmentPatientsLinear regression analysisState HospitalNeurosurgical proceduresLogistic regression
2006
Nonconvulsive Status Epilepticus in Children: Clinical and EEG Characteristics
Tay SK, Hirsch LJ, Leary L, Jette N, Wittman J, Akman CI. Nonconvulsive Status Epilepticus in Children: Clinical and EEG Characteristics. Epilepsia 2006, 47: 1504-1509. PMID: 16981867, DOI: 10.1111/j.1528-1167.2006.00623.x.Peer-Reviewed Original ResearchConceptsNonconvulsive status epilepticusConvulsive status epilepticusPeriodic lateralized epileptiform dischargesPediatric patientsStatus epilepticusEpileptiform dischargesDiagnosis of NCSEAcute hypoxic-ischemic injuryAntiepileptic drug regimenAcute medical illnessHypoxic-ischemic injuryComprehensive Epilepsy CenterContinuous electroencephalographic monitoringPeriodic epileptiform dischargesHeterogeneous clinical conditionYears of ageFrequent etiologyNeurological outcomeChart reviewDrug regimenAcute infectionAcute settingConvulsive seizuresPrompt recognitionRefractory epilepsy
2003
Tonic–Absence Seizures: An Underrecognized Seizure Type
Shih TT, Hirsch LJ. Tonic–Absence Seizures: An Underrecognized Seizure Type. Epilepsia 2003, 44: 461-465. PMID: 12614405, DOI: 10.1046/j.1528-1157.2003.39602.x.Peer-Reviewed Original ResearchConceptsSymptomatic generalized epilepsySeizure typesTonic seizuresGeneralized epilepsyAbsence seizuresMultiple seizure typesParoxysmal fast activityEpilepsy monitoring unitSlow spikeElectroclinical patternClinical patternStatic encephalopathyClinical correlatesClinical correlationTonic activityInternational LeagueFast activitySeizuresNormal cognitionPatientsEpilepsy diagnosisEpilepsyGPFAMonitoring unitEncephalopathy