2020
Nonepileptic Electroencephalographic Correlates of Episodic Increases in Intracranial Pressure
Sheikh ZB, Maciel CB, Dhakar MB, Hirsch LJ, Gilmore EJ. Nonepileptic Electroencephalographic Correlates of Episodic Increases in Intracranial Pressure. Journal Of Clinical Neurophysiology 2020, 39: 149-158. PMID: 32701765, DOI: 10.1097/wnp.0000000000000750.Peer-Reviewed Original Research
2013
Nonconvulsive seizures after subarachnoid hemorrhage: Multimodal detection and outcomes
Claassen J, Perotte A, Albers D, Kleinberg S, Schmidt JM, Tu B, Badjatia N, Lantigua H, Hirsch LJ, Mayer SA, Connolly ES, Hripcsak G. Nonconvulsive seizures after subarachnoid hemorrhage: Multimodal detection and outcomes. Annals Of Neurology 2013, 74: 53-64. PMID: 23813945, PMCID: PMC3775941, DOI: 10.1002/ana.23859.Peer-Reviewed Original ResearchConceptsRegional cerebral blood flowAcute brain injuryBrain injuryCerebral physiologic effectsCerebral perfusion pressureSecondary brain injuryBrain tissue oxygenationSubarachnoid hemorrhage patientsCerebral blood flowGlobal brain metabolismElevated heart rateComplex physiologic processBlood pressureNonconvulsive seizuresHemorrhage patientsPerfusion pressureSubarachnoid hemorrhageBrain metabolismFunctional outcomeIntracranial pressureSeizure onsetPhysiologic effectsHeart rateOnly seizuresBlood flow
2009
Continuous Electroencephalogram Monitoring in the Intensive Care Unit
Friedman D, Claassen J, Hirsch LJ. Continuous Electroencephalogram Monitoring in the Intensive Care Unit. Anesthesia & Analgesia 2009, 109: 506-523. PMID: 19608827, DOI: 10.1213/ane.0b013e3181a9d8b5.Peer-Reviewed Original ResearchConceptsContinuous EEG monitoringNonconvulsive seizuresIll patientsIntracranial pressureBrain functionContinuous electroencephalogram monitoringConvulsive status epilepticusIntensive care unitMajority of seizuresMultimodality brain monitoringPharmacological comaNeurologic outcomeNeurologic statusNeuronal injuryBrain ischemiaStatus epilepticusCare unitSecondary injurySubarachnoid hemorrhageCEEG monitoringClinical examinationElectroencephalogram monitoringSystemic abnormalitiesIntracranial EEG recordingsHigh risk
2008
Nonconvulsive Seizures in Traumatic Brain Injury: What You Don't See Can Hurt You
Hirsch LJ. Nonconvulsive Seizures in Traumatic Brain Injury: What You Don't See Can Hurt You. Epilepsy Currents 2008, 8: 97-99. PMID: 18596875, PMCID: PMC2442151, DOI: 10.1111/j.1535-7511.2008.00254.x.Peer-Reviewed Original ResearchLactate/pyruvate ratioPost-traumatic seizuresMicrodialysis lactate/pyruvate ratioTraumatic brain injury patientsBrain injury patientsIntracranial pressureTraumatic brain injuryPyruvate ratioSeizure groupInjury patientsBrain injuryMean lactate/pyruvate ratioSevere traumatic brain injury patientsNeurologic intensive care unitTraumatic brain injury (TBI) resultsHighest mean intracranial pressureIntensive care unitBrain injury resultsMean intracranial pressureRetrospective data analysisNonseizure patientsCerebral microdialysisNonconvulsive seizuresStatus epilepticusCare unit