2022
Sex differences in early and term placenta are conserved in adult tissues
Olney K, Plaisier S, Phung T, Silasi M, Perley L, O’Bryan J, Ramirez L, Kliman H, Wilson M. Sex differences in early and term placenta are conserved in adult tissues. Biology Of Sex Differences 2022, 13: 74. PMID: 36550527, PMCID: PMC9773522, DOI: 10.1186/s13293-022-00470-y.Peer-Reviewed Original ResearchConceptsFirst trimester placentaLate first trimesterTerm placentaTrimester placentaFirst trimesterAdult tissuesGene expressionSex differencesLifelong health outcomesSex-differential gene expressionGenetic sexInnate immune responseFull-term placentaSex-linked genesInnate immune genesImmune responsePlacenta samplesHealth outcomesBrain tissuePlacentaGametologous genesDifferent timepointsSex chromosomesImmune genesSexInsulin increases placental triglyceride as a potential mechanism for fetal adiposity in maternal obesity
Anam AK, Cooke KM, Dratver MB, O'Bryan JV, Perley LE, Guller SM, Hwang JJ, Taylor HS, Goedeke L, Kliman HJ, Vatner DF, Flannery CA. Insulin increases placental triglyceride as a potential mechanism for fetal adiposity in maternal obesity. Molecular Metabolism 2022, 64: 101574. PMID: 35970449, PMCID: PMC9440306, DOI: 10.1016/j.molmet.2022.101574.Peer-Reviewed Original ResearchConceptsDe novo lipogenesisFetal adiposityFatty acid uptakeMaternal obesityObese womenNormal weightExcess adiposityVillous explantsInsulin receptorNewborns of mothersNormal-weight womenAcid uptakePlacental villous explantsTranscription factor SREBP-1Insulin-like growth factor 2Effect of insulinFatty acid oxidationPlacental triglyceridesPlacental responsesElevated triglyceridesMaternal hyperglycemiaWeight womenGrowth factor 2Diabetes riskPlacental metabolism
2015
Social network and census tract-level influences on substance use among emerging adult males: An activity spaces approach
Gibson C, Perley L, Bailey J, Barbour R, Kershaw T. Social network and census tract-level influences on substance use among emerging adult males: An activity spaces approach. Health & Place 2015, 35: 28-36. PMID: 26176810, PMCID: PMC4637231, DOI: 10.1016/j.healthplace.2015.06.004.Peer-Reviewed Original Research
2010
FEASIBILITY OF CRANBERRY CAPSULE ADMINISTRATION AND CLEAN‐CATCH URINE COLLECTION IN LONG‐TERM CARE RESIDENTS
Juthani‐Mehta M, Perley L, Chen S, Dziura J, Gupta K. FEASIBILITY OF CRANBERRY CAPSULE ADMINISTRATION AND CLEAN‐CATCH URINE COLLECTION IN LONG‐TERM CARE RESIDENTS. Journal Of The American Geriatrics Society 2010, 58: 2028-2030. PMID: 20929476, PMCID: PMC2953731, DOI: 10.1111/j.1532-5415.2010.03080.x.Peer-Reviewed Original Research