Featured Publications
Development and validation of a prediction model for persistent functional impairment among older ICU survivors
Ferrante LE, Murphy TE, Leo‐Summers L, O'Leary JR, Vander Wyk B, Pisani MA, Gill TM. Development and validation of a prediction model for persistent functional impairment among older ICU survivors. Journal Of The American Geriatrics Society 2022, 71: 188-197. PMID: 36196998, PMCID: PMC9870848, DOI: 10.1111/jgs.18075.Peer-Reviewed Original ResearchConceptsPersistent functional impairmentICU hospitalizationFunctional impairmentValidation cohortICU admissionDevelopment cohortOlder Intensive Care Unit SurvivorsIntensive care unit survivorsOlder adultsOlder ICU survivorsMonths of dischargeHigh-risk survivorsCommunity-living participantsGood calibrationHospital lengthICU survivorsCritical illnessMedian agePrior hospitalizationFunctional recoveryNational HealthProbable dementiaHospitalizationHigh riskDepressive symptomsNeighborhood Socioeconomic Disadvantage and Disability After Critical Illness*
Falvey JR, Murphy TE, Leo-Summers L, Gill TM, Ferrante LE. Neighborhood Socioeconomic Disadvantage and Disability After Critical Illness*. Critical Care Medicine 2021, 50: 733-741. PMID: 34636807, PMCID: PMC9001742, DOI: 10.1097/ccm.0000000000005364.Peer-Reviewed Original ResearchConceptsNeighborhood socioeconomic disadvantageDisability burdenHigher disability burdenCritical illnessSocioeconomic disadvantageOlder adultsCritical illness survivorsLongitudinal cohort studyArea Deprivation IndexDisadvantaged neighborhoodsNon-Hispanic whitesDifferent functional tasksICU admissionICU dischargeICU survivorsCohort studyDischarge destinationHospital dischargeFunctional recoveryNeighborhood disadvantageAdjusted modelCare servicesSecondary analysisSecondary objectiveIllnessThe Combined Effects of Frailty and Cognitive Impairment on Post-ICU Disability among Older ICU Survivors
Ferrante LE, Murphy TE, Leo-Summers LS, Gahbauer EA, Pisani MA, Gill TM. The Combined Effects of Frailty and Cognitive Impairment on Post-ICU Disability among Older ICU Survivors. American Journal Of Respiratory And Critical Care Medicine 2019, 200: 107-110. PMID: 30883191, PMCID: PMC6603056, DOI: 10.1164/rccm.201806-1144le.Peer-Reviewed Original ResearchThe Association of Frailty With Post-ICU Disability, Nursing Home Admission, and Mortality A Longitudinal Study
Ferrante LE, Pisani MA, Murphy TE, Gahbauer EA, Leo-Summers LS, Gill TM. The Association of Frailty With Post-ICU Disability, Nursing Home Admission, and Mortality A Longitudinal Study. CHEST Journal 2018, 153: 1378-1386. PMID: 29559308, PMCID: PMC6026287, DOI: 10.1016/j.chest.2018.03.007.Peer-Reviewed Original ResearchConceptsNursing home admissionPost-ICU disabilityHome admissionCritical illnessFrailty statusGreater disabilityNew nursing home admissionsAssociation of frailtyLikelihood of deathOne-point increaseICU admissionICU survivorsICU outcomesMean agePrognostic informationPrefrailtyFried indexAdmissionFrailtyOlder personsParent cohortAnalytic sampleFunctional activityNonfrailtyDisabilityFactors Associated with Functional Recovery among Older Intensive Care Unit Survivors
Ferrante LE, Pisani MA, Murphy TE, Gahbauer EA, Leo-Summers LS, Gill TM. Factors Associated with Functional Recovery among Older Intensive Care Unit Survivors. American Journal Of Respiratory And Critical Care Medicine 2016, 194: 299-307. PMID: 26840348, PMCID: PMC4970594, DOI: 10.1164/rccm.201506-1256oc.Peer-Reviewed Original ResearchConceptsHigher body mass indexOlder ICU survivorsIntensive care unitBody mass indexFunctional recoveryICU survivorsICU admissionMass indexOlder Intensive Care Unit SurvivorsIntensive care unit survivorsOlder adultsPoor functional recoveryCritical illnessIndependent predictorsCare unitMultivariable analysisFunctional outcomePremorbid functionPotential predictorsVision impairmentAdmissionSurvivorsAnalytic sampleFunctional activityMonthsFeasibility of In-Hospital Administration of a Tool to Predict Persistent Post-ICU Functional Impairment Among Older ICU Survivors A Pilot Study
Stevenson J, Murphy T, Tessier-Sherman B, Pisani M, Gill T, Ferrante L. Feasibility of In-Hospital Administration of a Tool to Predict Persistent Post-ICU Functional Impairment Among Older ICU Survivors A Pilot Study. CHEST Critical Care 2024, 2: 100093. DOI: 10.1016/j.chstcc.2024.100093.Peer-Reviewed Original ResearchRisk prediction toolsICU survivorsIn-hospital administrationOlder adultsFunctional impairmentPilot studyIn-hospital mobilityOlder ICU survivorsDevelopment of risk prediction modelsHospital-related factorsIn-hospital factorsPresence of deliriumRisk prediction modelModel discriminationPersistent functional impairmentStatistical significanceHospital settingStudy designFeasibility thresholdDaily activitiesIncreased riskInternational Consensus ConferenceConsensus conferenceSurvivorsCritical illness
2024
Association Between Restricting Symptoms and Disability After Critical Illness Among Older Adults.
Jain S, Han L, Gahbauer E, Leo-Summers L, Feder S, Ferrante L, Gill T. Association Between Restricting Symptoms and Disability After Critical Illness Among Older Adults. Critical Care Medicine 2024, 52: 1816-1827. PMID: 39298623, DOI: 10.1097/ccm.0000000000006427.Peer-Reviewed Original ResearchActivities of daily livingAssociated with increased disabilityDaily livingOlder adultsRestricting symptomsInstrumental activities of daily livingCommunity-living older adultsICU hospitalizationMultivariable Poisson regression modelsCommunity-living adultsOlder ICU survivorsAge of participantsPoisson regression modelsSurvive critical illnessCritical illnessQuality of lifeInstrumental activitiesICU survivorsProspective longitudinal studyLength of stayPost-ICUIncreased disabilityMonthly interviewsICU length of stayPre-ICU
2023
Changes in Restricting Symptoms after Critical Illness among Community-Living Older Adults.
Jain S, Han L, Gahbauer E, Leo-Summers L, Feder S, Ferrante L, Gill T. Changes in Restricting Symptoms after Critical Illness among Community-Living Older Adults. American Journal Of Respiratory And Critical Care Medicine 2023, 208: 1206-1215. PMID: 37769149, PMCID: PMC10868351, DOI: 10.1164/rccm.202304-0693oc.Peer-Reviewed Original ResearchConceptsNeighborhood-level socioeconomic disadvantageCritical illnessIntensive care unitHospital dischargeCommunity-living older adultsOlder adultsOlder ICU survivorsPost-ICU careSocioeconomic disadvantageProspective longitudinal studyQuality of lifeICU admissionICU survivorsCare unitFunctional recoverySymptom managementMultiple symptomsThird monthThree monthsSymptomsIllnessRestricted activityVulnerable subgroupsFirst monthMonths
2022
Long-term recovery after critical illness in older adults
Kaushik R, Ferrante LE. Long-term recovery after critical illness in older adults. Current Opinion In Critical Care 2022, 28: 572-580. PMID: 35950731, PMCID: PMC9458622, DOI: 10.1097/mcc.0000000000000981.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOlder ICU patientsPost-ICU recoveryCritical illnessGeriatric syndromesLong-term recoveryOlder adultsICU patientsRisk factorsIncidence of frailtyOlder ICU survivorsTransitional care programLong-term outcomesContinuum of careSocial isolationRecent epidemiologic workSocial risk factorsICU survivorsRecent literature pertainingUnique needsRecent longitudinal studiesNew disabilityWorse outcomesFunctional declineCare programSyndrome
2020
Home Health Rehabilitation Utilization Among Medicare Beneficiaries Following Critical Illness
Falvey JR, Murphy TE, Gill TM, Stevens‐Lapsley J, Ferrante LE. Home Health Rehabilitation Utilization Among Medicare Beneficiaries Following Critical Illness. Journal Of The American Geriatrics Society 2020, 68: 1512-1519. PMID: 32187664, PMCID: PMC7712590, DOI: 10.1111/jgs.16412.Peer-Reviewed Original ResearchConceptsRehabilitation visitsCritical illnessMedicare beneficiariesICU survivorsHome healthPost-acute care facilitiesIntensive care unit survivorsDays of dischargeHigher baseline disabilityAssessment Information SetPost-hospitalization periodRural settingsHome-based rehabilitationHH careHH servicesHH settingHospice transferLeast disabilityMore comorbiditiesBaseline disabilityICU stayElixhauser scoreHighest tertileRehabilitation utilizationDischarge planning
2019
Patient-Centered Outcomes in Critical Illness: Will My Patient Be Functionally and Cognitively Intact?
Geer JH, Qi W, Ferrante LE. Patient-Centered Outcomes in Critical Illness: Will My Patient Be Functionally and Cognitively Intact? Seminars In Respiratory And Critical Care Medicine 2019, 40: 638-647. PMID: 31826264, DOI: 10.1055/s-0039-1698379.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements