1999
Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles
Palmatier M, Kang A, Kidd K. Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles. Biological Psychiatry 1999, 46: 557-567. PMID: 10459407, DOI: 10.1016/s0006-3223(99)00098-0.Peer-Reviewed Original ResearchConceptsRestriction site polymorphismsSingle nucleotide polymorphismsAllele frequenciesDifferent population frequenciesControl allele frequenciesEnzyme activity levelsAncestral alleleCandidate genesPopulation-based association studyAssociation studiesSite polymorphismFirst global surveyNucleotide polymorphismsAllelesEnzyme activityPopulation frequencyPolymorphismDifferent populationsCOMT enzyme activityActivity alleleLow-activity alleleGenesProteinGlobal variationPopulation
1993
Associations of disease with genetic markers: Déjà vu all over again
Kidd K. Associations of disease with genetic markers: Déjà vu all over again. American Journal Of Medical Genetics 1993, 48: 71-73. PMID: 8362928, DOI: 10.1002/ajmg.1320480202.Peer-Reviewed Original Research
1991
Trials and tribulations in the search for genes causing neuropsychiatric disorders
Kidd K. Trials and tribulations in the search for genes causing neuropsychiatric disorders. Biodemography And Social Biology 1991, 38: 163-178. PMID: 1801198, DOI: 10.1080/19485565.1991.9988785.Peer-Reviewed Original Research
1987
Family-Genetic Studies and Identification of Valid Diagnostic Categories in Adult and Child Psychiatry
Leckman J, Weissman M, Pauls D, Kidd K. Family-Genetic Studies and Identification of Valid Diagnostic Categories in Adult and Child Psychiatry. The British Journal Of Psychiatry 1987, 151: 39-44. PMID: 3315088, DOI: 10.1192/bjp.151.1.39.Peer-Reviewed Original Research
1986
Family-Genetic Studies of Psychiatric Disorders: Developing Technologies
Weissman M, Merikangas K, John K, Wickramaratne P, Prusoff B, Kidd K. Family-Genetic Studies of Psychiatric Disorders: Developing Technologies. JAMA Psychiatry 1986, 43: 1104-1116. PMID: 3532996, DOI: 10.1001/archpsyc.1986.01800110090012.Peer-Reviewed Original ResearchMeSH KeywordsData CollectionEpidemiologic MethodsGenetic LinkageGenetic TechniquesHumansMental DisordersResearch DesignRiskConceptsPsychiatric disordersFamily genetic studiesMode of transmissionFuture genetic linkage studiesPsychiatric illnessChildhood manifestationsClinical practiceDiagnostic proceduresStudy designDisordersGenetic linkage studiesFamily studiesHomogeneous subgroupsLinkage studiesAdultsInformative families
1984
Psychopathology in the Children (Ages 6–18) of Depressed and Normal Parents
WEISSMAN M, PRUSOFF B, GAMMON G, MERIKANGAS K, LECKMAN J, KIDD K. Psychopathology in the Children (Ages 6–18) of Depressed and Normal Parents. Journal Of The American Academy Of Child & Adolescent Psychiatry 1984, 23: 78-84. PMID: 6693680, DOI: 10.1097/00004583-198401000-00011.Peer-Reviewed Original ResearchConceptsDSM-III diagnosesFirst-degree relativesMajor depressionPsychiatric disordersProbands' first-degree relativesChildren of probandsCommon psychiatric disordersDirect interview studyFamily history studyClinical statusPsychiatric illnessNormal controlsDepressed probandsPsychological symptomsSuicidal behaviorEarly onsetDiagnosisDepressionSignificant predictorsProbandsAttention deficitsChildrenRiskEmotional problemsNormal parentsPsychiatric Disorders in the Relatives of Probands With Affective Disorders: The Yale University—National Institute of Mental Health Collaborative Study
Weissman M, Gershon E, Kidd K, Prusoff B, Leckman J, Dibble E, Hamovit J, Thompson W, Pauls D, Guroff J. Psychiatric Disorders in the Relatives of Probands With Affective Disorders: The Yale University—National Institute of Mental Health Collaborative Study. JAMA Psychiatry 1984, 41: 13-21. PMID: 6691780, DOI: 10.1001/archpsyc.1984.01790120015003.Peer-Reviewed Original ResearchConceptsRelatives of probandsMajor depressionPsychiatric disordersAffective disordersMental Health Collaborative StudyComparable diagnostic criteriaFirst-degree relativesComparability of ratesDiagnostic criteriaBipolar disorderDepressed probandsMost disordersDisordersProbandsFamily studiesCollaborative studyRelativesAmbulatoryIllness
1982
An Evaluation of the Family History Method for Ascertaining Psychiatric Disorders
Thompson W, Orvaschel H, Prusoff B, Kidd K. An Evaluation of the Family History Method for Ascertaining Psychiatric Disorders. JAMA Psychiatry 1982, 39: 53-58. PMID: 7055408, DOI: 10.1001/archpsyc.1982.04290010031006.Peer-Reviewed Original Research
1978
Research Designs for the Study of Gene-Environment Interactions in Psychiatric Disorders: Report of a Foundations Fund for Research in Psychiatry Panel
Kidd K, Matthysee S. Research Designs for the Study of Gene-Environment Interactions in Psychiatric Disorders: Report of a Foundations Fund for Research in Psychiatry Panel. JAMA Psychiatry 1978, 35: 925-932. PMID: 678045, DOI: 10.1001/archpsyc.1978.01770320019001.Peer-Reviewed Original ResearchConceptsGenetic variantsUnrelated individualsIndividual genetic variantsGenetic variationDifferent genetic variantsExtended pedigreesGenetic heterogeneityGene-environment interactionsGenetic hypothesisPhenotypeDiagnostic phenotypesFamilyGeneticsVariantsTraitsIndividual susceptibilitySpecific hypothesesSuch studiesHypothesisEnvironmental contributionsPedigreeGenotypesSusceptibility