2024
Language sentiment predicts changes in depressive symptoms
Hur J, Heffner J, Feng G, Joormann J, Rutledge R. Language sentiment predicts changes in depressive symptoms. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2321321121. PMID: 39284070, PMCID: PMC11441484, DOI: 10.1073/pnas.2321321121.Peer-Reviewed Original ResearchConceptsLinguistic Inquiry and Word CountDepressive symptomsCurrent moodAssociated with current moodDecision-making taskAssess depressive symptomsThree-week follow-upLanguage sentimentPatient Health QuestionnaireSymptom changePrevalence of depressionPsychiatric symptomsMood dynamicsMomentary happinessPHQ-9Past researchLinguistic responsesDepressionHealth QuestionnaireHuman ratersWord countMoodSocietal health concernSymptomsRaters
2023
Cognitive behavioral therapy following esketamine for major depression and suicidal ideation for relapse prevention: The CBT-ENDURE randomized clinical trial study protocol
Kitay B, Murphy E, Macaluso M, Corlett P, Hershenberg R, Joormann J, Martinez-Kaigi V, Nikayin S, Rhee T, Sanacora G, Shelton R, Thase M, Wilkinson S. Cognitive behavioral therapy following esketamine for major depression and suicidal ideation for relapse prevention: The CBT-ENDURE randomized clinical trial study protocol. Psychiatry Research 2023, 330: 115585. PMID: 37935086, DOI: 10.1016/j.psychres.2023.115585.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyMajor depressionSuicidal ideationRelapse preventionBehavioral therapyStudy protocolHigh riskClinical trial study protocolLong-term treatment approachKey secondary outcomesTrial study protocolHigh relapse rateHigh-risk populationSignificant suicidal ideationHospital dischargeSecondary outcomesPrimary outcomeRelapse rateFeasibility trialEsketamineTreatment approachesPatientsSuicide attemptsTherapySupplemental indicationsOn the impulsivity path: Examining the unique and conjoint relations between emotion‐ and non‐emotion‐related impulsivity, internalizing symptoms, alcohol use, and physical health parameters
Javelle F, Schlagheck M, Broos H, Timpano K, Joormann J, Zimmer P, Johnson S. On the impulsivity path: Examining the unique and conjoint relations between emotion‐ and non‐emotion‐related impulsivity, internalizing symptoms, alcohol use, and physical health parameters. Journal Of Clinical Psychology 2023, 80: 339-354. PMID: 37883120, PMCID: PMC11170548, DOI: 10.1002/jclp.23608.Peer-Reviewed Original ResearchConceptsPhysical health parametersPoor sleep qualityPhysical activitySleep qualityHealth parametersAlcohol useAim 1Feelings Trigger ActionPsychopathology symptomsPotential treatment targetLack of followAssociation of ERIFollow-ThroughInternalizing symptomsCombined associationsTreatment targetsSymptomsAim 2Physical healthModerate associationMeasures of impulsivityAssociationControl comparisonSeparate path modelsImpulsivitySeeing Red: Distraction Influences Visual Attention for Anger but Not for Other Negative Emotions
Rutherford A, Raila H, Blicher A, Vanderlind W, Joormann J. Seeing Red: Distraction Influences Visual Attention for Anger but Not for Other Negative Emotions. Emotion 2023, 23: 1224-1235. PMID: 36107655, DOI: 10.1037/emo0001136.Peer-Reviewed Original ResearchConceptsEmotion regulation strategiesRegulation strategiesFilm clipsState anxietyEmotion-eliciting film clipsEmotion-eliciting stimuliEmotional film clipsCurrent affective stateNegative emotional statesAttention allocation strategyCognitive reappraisalEmotion regulationEmotional informationVisual attentionNegative emotionsNegative affectDistraction conditionEmotional statesAffective statesNatural viewingEye trackingOverall functioningVital skillEffect of conditionCommunity participantsChoosing to Avoid the Positive? Emotion Regulation Strategy Choice in Depression
Millgram Y, Lakan S, Joormann J, Nahum M, Shimony O, Tamir M. Choosing to Avoid the Positive? Emotion Regulation Strategy Choice in Depression. Journal Of Psychopathology And Clinical Science 2023, 132: 669-680. PMID: 37261782, DOI: 10.1037/abn0000835.Peer-Reviewed Original ResearchConceptsEmotion regulation strategiesPleasant emotionsUnpleasant emotionsMDD participantsRegulation strategiesPleasant affectNondepressed individualsStrategy choiceMajor depressive disorderEcological momentary assessmentStrong motivationPositive ruminationNegative ruminationUnpleasant affectPleasant stimuliStrategy useBehavioral tasksEmotionsDaily lifeStudy 1Study 2Momentary assessmentAffectMotivationRuminationCortisol reactivity to a laboratory stressor predicts increases in depressive symptoms in perinatal and nulliparous women during population-level stress
Beech A, Edelman A, Yatziv T, Rutherford H, Joormann J, Gadassi-Polack R. Cortisol reactivity to a laboratory stressor predicts increases in depressive symptoms in perinatal and nulliparous women during population-level stress. Journal Of Affective Disorders 2023, 340: 33-41. PMID: 37499916, PMCID: PMC10529046, DOI: 10.1016/j.jad.2023.07.093.Peer-Reviewed Original ResearchConceptsDepressive symptomsNulliparous womenCortisol reactivityLaboratory stressorHigh-risk groupDepressive symptom questionnairesBiomarkers of riskPsychosocial stress testCurrent depressive symptomsCOVID-19Salivary cortisol samplesPopulation-level stressorGestational weeksSymptom questionnairePerinatal periodNeed of interventionDepression riskCortisol levelsSymptomsCortisol samplesPregnancyWomenCOVID-19 pandemicStress testRiskCognitive flexibility and emotion regulation: Dual layers of resilience against the emergence of paranoia
Deng W, Acquah K, Joormann J, Cannon T. Cognitive flexibility and emotion regulation: Dual layers of resilience against the emergence of paranoia. Behaviour Research And Therapy 2023, 167: 104360. PMID: 37413786, DOI: 10.1016/j.brat.2023.104360.Peer-Reviewed Original ResearchConceptsEmotion regulation abilitiesHigher cognitive flexibilityCognitive flexibilityEmotion regulationRegulation abilityParanoid beliefsBetter emotion regulation abilityGreater emotion regulation difficultiesLower cognitive flexibilityEmotion regulation difficultiesSelf-report measuresSevere paranoiaCognitive vulnerabilityRegulation difficultiesCognitive inflexibilityAffective statesLower paranoiaBiased beliefsParanoiaEarly interventionBeliefsLow abilityInflexibilityIndividualsAbilityInterplay between uncertainty intolerance, emotion regulation, cognitive flexibility, and psychopathology during the COVID-19 pandemic: a multi-wave study
Godara M, Everaert J, Sanchez-Lopez A, Joormann J, De Raedt R. Interplay between uncertainty intolerance, emotion regulation, cognitive flexibility, and psychopathology during the COVID-19 pandemic: a multi-wave study. Scientific Reports 2023, 13: 9854. PMID: 37330557, PMCID: PMC10276821, DOI: 10.1038/s41598-023-36211-3.Peer-Reviewed Original ResearchConceptsIntolerance of uncertaintyEmotion regulation difficultiesCognitive controlMulti-wave studyRegulation difficultiesCognitive flexibilityEmotion regulationMental healthMaladaptive emotion regulationProtective factorsUncertainty intoleranceIndividual differencesMediation analysisMental health burdenCOVID-19 pandemicStress resilienceRisk factorsPsychopathologySignificant mental health burdenOnline assessmentLongitudinal changesNegative effectsDifficultiesHealth burdenAnxietyEmotion regulation and disordered eating behaviour in youths: Two daily‐diary studies
Dworschak C, Polack R, Winschel J, Joormann J, Kober H. Emotion regulation and disordered eating behaviour in youths: Two daily‐diary studies. European Eating Disorders Review 2023, 31: 655-669. PMID: 37293697, DOI: 10.1002/erv.2993.Peer-Reviewed Original ResearchConceptsEmotion regulationNegative affectPositive emotion regulationMaladaptive emotion regulationDisorder riskDaily diary designDaily diary studyUse of ruminationNegative emotionsDiary designRestrictive eatingWeight concernsRuminationPrevious researchCognitionWave 1YouthAffectEatingEmotionsCOVID-19 pandemicAdolescenceHigh levelsPresent studyBehaviorNeural responses to reward valence and magnitude from pre- to early adolescence
Polack R, Mollick J, Keren H, Joormann J, Watts R. Neural responses to reward valence and magnitude from pre- to early adolescence. NeuroImage 2023, 275: 120166. PMID: 37178821, PMCID: PMC10311119, DOI: 10.1016/j.neuroimage.2023.120166.Peer-Reviewed Original ResearchConceptsReward processingEarly adolescenceNeural responsesTrial typesMonetary incentive delay taskIncentive delay taskNeural reactivityNeural basisAdolescent developmentDelay taskIncentive valenceFunctional neuroanatomyNeural activationMotivational behaviorPreadolescent childrenReward circuitrySuccess feedbackAdolescenceDevelopmental changesValenceIndependent subsamplesStatus differencesBiological sexEffect sizeLarge sampleAttentional biases in facial emotion processing in individuals at clinical high risk for psychosis
Williams T, Cohen A, Sanchez-Lopez A, Joormann J, Mittal V. Attentional biases in facial emotion processing in individuals at clinical high risk for psychosis. European Archives Of Psychiatry And Clinical Neuroscience 2023, 273: 1825-1835. PMID: 36920535, PMCID: PMC10502185, DOI: 10.1007/s00406-023-01582-1.Peer-Reviewed Original ResearchConceptsFacial emotion processingEye-tracking paradigmAttentional biasesClinical high riskSocial functioningEmotion processingNegative symptomsCHR individualsAttentional bias indicesGlobal social functioningPoor social functioningFearful facesHappy facesNeutral facesPsychosis exhibitCHR groupSuch biasesBias indexComorbid disordersClinical InterviewFunctioningPrevious researchBiasesCHR syndromeDepressive symptomsUtility of Wrist-Wearable Data for Assessing Pain, Sleep, and Anxiety Outcomes After Traumatic Stress Exposure
Straus L, An X, Ji Y, McLean S, Neylan T, Cakmak A, Richards A, Clifford G, Liu M, Zeng D, House S, Beaudoin F, Stevens J, Linnstaedt S, Germine L, Bollen K, Rauch S, Haran J, Storrow A, Lewandowski C, Musey P, Hendry P, Sheikh S, Jones C, Punches B, Kurz M, Swor R, Hudak L, Seamon M, Datner E, Chang A, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, O’Neil B, Sergot P, Sanchez L, Bruce S, Miller M, Pietrzak R, Joormann J, Barch D, Pizzagalli D, Sheridan J, Harte S, Elliott J, Kessler R, Ressler K, Koenen K. Utility of Wrist-Wearable Data for Assessing Pain, Sleep, and Anxiety Outcomes After Traumatic Stress Exposure. JAMA Psychiatry 2023, 80: 220-229. PMID: 36630119, PMCID: PMC9857758, DOI: 10.1001/jamapsychiatry.2022.4533.Peer-Reviewed Original ResearchConceptsTraumatic stress exposureAdverse posttraumatic neuropsychiatric sequelaeEmergency departmentStress exposureNeuropsychiatric sequelaeGreater pain severityPain severityDerivation cohortNeuropsychiatric symptomsMean ageStudy criteriaSerial assessmentSleep disruptionMAIN OUTCOMEHigh incidenceUseful biomarkerBaseline assessmentPainSymptom severityDiverse cohortInformed consentPatientsSymptom domainsSleepDisadvantaged populations“Don't [ruminate], be happy”: A cognitive perspective linking depression and anhedonia
Rutherford A, McDougle S, Joormann J. “Don't [ruminate], be happy”: A cognitive perspective linking depression and anhedonia. Clinical Psychology Review 2023, 101: 102255. PMID: 36871425, DOI: 10.1016/j.cpr.2023.102255.Peer-Reviewed Original ResearchConceptsPositive affectNegative affectSustained negative affectCognitive constructsCognitive theoryCognitive perspectiveLack of pleasureCognitive deficitsSpecific thoughtsIntervention effortsDifferent theoretical lensesAffectRuminationAnhedoniaDeficitsExtant literatureMemoryDepressionHallmark featureComputational modelingTheoretical lensesEnvironmental cuesLess focusDebilitating disorderCuesStructural inequities contribute to racial/ethnic differences in neurophysiological tone, but not threat reactivity, after trauma exposure
Harnett N, Fani N, Carter S, Sanchez L, Rowland G, Davie W, Guzman C, Lebois L, Ely T, van Rooij S, Seligowski A, Winters S, Grasser L, Musey P, Seamon M, House S, Beaudoin F, An X, Zeng D, Neylan T, Clifford G, Linnstaedt S, Germine L, Bollen K, Rauch S, Haran J, Storrow A, Lewandowski C, Hendry P, Sheikh S, Jones C, Punches B, Swor R, Hudak L, Pascual J, Harris E, Chang A, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, Bruce S, Miller M, Pietrzak R, Joormann J, Barch D, Pizzagalli D, Harte S, Elliott J, Kessler R, Koenen K, McLean S, Jovanovic T, Stevens J, Ressler K. Structural inequities contribute to racial/ethnic differences in neurophysiological tone, but not threat reactivity, after trauma exposure. Molecular Psychiatry 2023, 28: 2975-2984. PMID: 36725899, PMCID: PMC10615735, DOI: 10.1038/s41380-023-01971-x.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderAmygdala connectivityAmygdala reactivityTrauma exposurePrefrontal cortexPTSD symptomsDorsal anterior cingulate cortexAnterior cingulate cortexFunctional magnetic resonance imagingMagnetic resonance imagingGreater amygdala connectivityDorsolateral prefrontal cortexSymptoms 3Trauma outcomesSkin conductance levelCingulate cortexEthnic groupsEthnic disparitiesResonance imagingMultisite longitudinal studyStress disorderTwo weeksEthnic variabilityWhite individualsBlack participantsDevelopment of a model to predict combined antidepressant medication and psychotherapy treatment response for depression among veterans
Bossarte R, Ross E, Liu H, Turner B, Bryant C, Zainal N, Puac-Polanco V, Ziobrowski H, Cui R, Cipriani A, Furukawa T, Leung L, Joormann J, Nierenberg A, Oslin D, Pigeon W, Post E, Zaslavsky A, Zubizarreta J, Luedtke A, Kennedy C, Kessler R. Development of a model to predict combined antidepressant medication and psychotherapy treatment response for depression among veterans. Journal Of Affective Disorders 2023, 326: 111-119. PMID: 36709831, PMCID: PMC9975041, DOI: 10.1016/j.jad.2023.01.082.Peer-Reviewed Original ResearchConceptsPsychotherapy treatment responseSelf-report assessmentsPsychological resilienceSelf-ReportRecent stressorsDepressed patientsGeneralizability of resultsSheehan Disability ScaleNational sampleTreatment responseImportant predictorLearning modelDepression treatmentParallel informationLikely responseSample definitionPsychotherapyTraining samplesStressorsClinician assessmentDisability ScaleGeneralizabilityInventoryVeteransDepressionChildhood adversities and risk of posttraumatic stress disorder and major depression following a motor vehicle collision in adulthood
Ziobrowski H, Holt-Gosselin B, Petukhova M, King A, Lee S, House S, Beaudoin F, An X, Stevens J, Zeng D, Neylan T, Clifford G, Linnstaedt S, Germine L, Bollen K, Rauch S, Haran J, Storrow A, Lewandowski C, Musey P, Hendry P, Sheikh S, Jones C, Punches B, Kurz M, Swor R, Hudak L, Pascual J, Seamon M, Harris E, Pearson C, Merchant R, Domeier R, Rathlev N, O'Neil B, Sergot P, Sanchez L, Bruce S, Miller M, Pietrzak R, Joormann J, Barch D, Pizzagalli D, Harte S, Elliott J, Ressler K, McLean S, Koenen K, Kessler R. Childhood adversities and risk of posttraumatic stress disorder and major depression following a motor vehicle collision in adulthood. Epidemiology And Psychiatric Sciences 2023, 32: e1. PMID: 36624694, PMCID: PMC9879881, DOI: 10.1017/s2045796022000798.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderAdverse posttraumatic neuropsychiatric sequelaeChildhood adversityEmotional abuseStress disorderEmotional neglectChronic posttraumatic stress disorderSelf-report criteriaPeritraumatic symptomsTraumatic eventsPTSD ChecklistSexual abusePhysical neglectMajor depressive episodeMotor vehicle collisionsPhysical abuseDSM-5CA measuresBullyingAbuseStrongest predictorAdversityTrauma studiesDichotomous measureExposure frequencyThe effect of attention bias modification on depressive symptoms in a comorbid sample: a randomized controlled trial
Bø R, Kraft B, Pedersen M, Joormann J, Jonassen R, Osnes K, Harmer C, Landrø N. The effect of attention bias modification on depressive symptoms in a comorbid sample: a randomized controlled trial. Psychological Medicine 2023, 53: 6389-6396. PMID: 36617964, PMCID: PMC10520597, DOI: 10.1017/s0033291722003956.Peer-Reviewed Original ResearchConceptsBeck Depression Inventory-IIDepressive symptomsDouble-blind randomized sham-controlled trialSham conditionRandomized sham-controlled trialSham-controlled trialLong-term outcomesMajor depressive episodeMajor depressive disorderSecondary outcomesPrimary outcomeDepressive episodeDepressive disorderLong-term effectsComorbid disordersComorbid anxietyComorbid sampleConsecutive daysInventory-IIPredictor analysisInventory scoresTotal scoreSymptomsEffects of ABMClinical samplesUse of serial smartphone-based assessments to characterize diverse neuropsychiatric symptom trajectories in a large trauma survivor cohort
Beaudoin F, An X, Basu A, Ji Y, Liu M, Kessler R, Doughtery R, Zeng D, Bollen K, House S, Stevens J, Neylan T, Clifford G, Jovanovic T, Linnstaedt S, Germine L, Rauch S, Haran J, Storrow A, Lewandowski C, Musey P, Hendry P, Sheikh S, Jones C, Punches B, Kurz M, Swor R, Murty V, McGrath M, Hudak L, Pascual J, Datner E, Chang A, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, Neil B, Sergot P, Sanchez L, Bruce S, Baker J, Joormann J, Miller M, Pietrzak R, Barch D, Pizzagalli D, Sheridan J, Smoller J, Harte S, Elliott J, Koenen K, Ressler K, McLean S. Use of serial smartphone-based assessments to characterize diverse neuropsychiatric symptom trajectories in a large trauma survivor cohort. Translational Psychiatry 2023, 13: 4. PMID: 36609484, PMCID: PMC9823011, DOI: 10.1038/s41398-022-02289-y.Peer-Reviewed Original ResearchSocial impression formation and depression: examining cognitive flexibility and bias
Deng W, Cannon T, Joormann J. Social impression formation and depression: examining cognitive flexibility and bias. Cognition & Emotion 2023, 37: 137-146. PMID: 36607322, DOI: 10.1080/02699931.2023.2165043.Peer-Reviewed Original ResearchConceptsSocial impression formationImpression formationImpression ratingsNegative interpretation biasSocial interaction partnersFuture social interactionsDepressive symptomsCognitive flexibilityInterpretation biasNegative interpretationsNegative contextPositive contextNegative evaluationSocial situationsPositive interpretationSocial interactionScenario typesSocial isolationInteraction partnersRatingsDepressionTaskNovel charactersScenario outcomesBias
2022
Derivation and Validation of a Brief Emergency Department-Based Prediction Tool for Posttraumatic Stress After Motor Vehicle Collision
Jones C, An X, Ji Y, Liu M, Zeng D, House S, Beaudoin F, Stevens J, Neylan T, Clifford G, Jovanovic T, Linnstaedt S, Germine L, Bollen K, Rauch S, Haran J, Storrow A, Lewandowski C, Musey P, Hendry P, Sheikh S, Punches B, Lyons M, Kurz M, Swor R, McGrath M, Hudak L, Pascual J, Seamon M, Datner E, Harris E, Chang A, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, O'Neil B, Sergot P, Sanchez L, Bruce S, Miller M, Pietrzak R, Joormann J, Barch D, Pizzagalli D, Sheridan J, Smoller J, Harte S, Elliott J, Koenen K, Ressler K, Kessler R, McLean S. Derivation and Validation of a Brief Emergency Department-Based Prediction Tool for Posttraumatic Stress After Motor Vehicle Collision. Annals Of Emergency Medicine 2022, 81: 249-261. PMID: 36328855, PMCID: PMC11181458, DOI: 10.1016/j.annemergmed.2022.08.011.Peer-Reviewed Original ResearchConceptsMotor vehicle collisionsPosttraumatic stress symptomsValidation cohortSubstantial posttraumatic stress symptomsStress symptomsVehicle collisionsRisk-stratify individualsClinical decision support toolEmergency department patientsPersistent posttraumatic stress symptomsPreventive intervention trialNumber of EDsEase of administrationDerivation cohortPrimary outcomeDepartment patientsIntervention trialsBaseline healthHigh riskSymptomsCohortExternal validationPsychological recoveryDiscriminative abilityPosttraumatic stress