2021
Innate immunity in latent autoimmune diabetes in adults
Huang J, Pearson JA, Wong FS, Wen L, Zhou Z. Innate immunity in latent autoimmune diabetes in adults. Diabetes/Metabolism Research And Reviews 2021, 38: e3480. PMID: 34156143, PMCID: PMC8813511, DOI: 10.1002/dmrr.3480.Peer-Reviewed Original ResearchConceptsType 1 diabetesDendritic cellsImmune cellsT cellsInnate immunityPathogenesis of LADALatent autoimmune diabetesAdaptive immune cellsPancreas of patientsType 2 diabetesImmune-associated genesIslet β-cellsAutoimmune diabetesClinical featuresImmunological reasonsAutoimmune diseasesRat modelB cellsDiabetesΒ-cellsImmunityPotential rolePathogenesisLADADisease
2016
Neutrophils in type 1 diabetes
Huang J, Xiao Y, Xu A, Zhou Z. Neutrophils in type 1 diabetes. Journal Of Diabetes Investigation 2016, 7: 652-663. PMID: 27181374, PMCID: PMC5009125, DOI: 10.1111/jdi.12469.Peer-Reviewed Original ResearchConceptsType 1 diabetesImmune cellsDiabetogenic T cell responseAutoimmune type 1 diabetesType 1 diabetes pathogenesisType 1 diabetes developmentΒ-cellsInsulin-producing pancreatic β-cellsProgression of insulitisT cell responsesFirst immune cellsNon-immune cellsImmune cell typesPancreatic β-cellsDendritic cellsDiabetes developmentAutoimmune diseasesDegranulation productsDiabetes pathogenesisExtracellular trapsT cellsDiabetesCell responsesNeutrophilsIslet cells