Exploratory analysis of genetic variants influencing molecular traits in cerebral cortex of suicide completers
Rodríguez‐López M, Martínez‐Magaña J, Cabrera‐Mendoza B, Genis‐Mendoza A, García‐Dolores F, López‐Armenta M, Flores G, Vázquez‐Roque R, Nicolini H. Exploratory analysis of genetic variants influencing molecular traits in cerebral cortex of suicide completers. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2019, 183: 26-37. PMID: 31418530, DOI: 10.1002/ajmg.b.32752.Peer-Reviewed Original ResearchConceptsExpression quantitative trait lociQuantitative trait lociTrait lociExpression of genesGene expressionGenetic variantsMethylation quantitative trait lociGene expression regulationExpression regulationCandidate genetic variantsDNA methylationMolecular traitsTranscription factorsEnhancer activityCell organizationRegulatory mechanismsGenetic factorsGenotype dataMultiple biological systemsLociGenesExpressionBiological systemsRegulationVariantsIdentification of gene ontology and pathways implicated in suicide behavior: Systematic review and enrichment analysis of GWAS studies
González‐Castro T, Tovilla‐Zárate C, Genis‐Mendoza A, Juárez‐Rojop I, Nicolini H, López‐Narváez M, Martínez‐Magaña J. Identification of gene ontology and pathways implicated in suicide behavior: Systematic review and enrichment analysis of GWAS studies. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2019, 180: 320-329. PMID: 31045331, DOI: 10.1002/ajmg.b.32731.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesBiological process gene ontologyGene OntologyProtein localizationPositive regulationKEGG pathwaysEnrichment analysisGenomes (KEGG) biological pathwaysHeterotypic cell-cell adhesionCell-cell adhesionGlucose importKyoto EncyclopediaGO analysisCardiomyopathy pathwaysGWAS studiesBiological pathwaysAssociation studiesGenesGenetic contributorsMultiple large-scale studiesEndopeptidase activityInsulin stimulusPathwayRegulationMuscle cell contraction