2023
Cross-Species Convergence of Brain Transcriptomic and Epigenomic Findings in Posttraumatic Stress Disorder: A Systematic Review
Núñez-Rios D, Martínez-Magaña J, Nagamatsu S, Krystal J, Martínez-González K, Giusti-Rodríguez P, Montalvo-Ortiz J. Cross-Species Convergence of Brain Transcriptomic and Epigenomic Findings in Posttraumatic Stress Disorder: A Systematic Review. Complex Psychiatry 2023, 9: 100-118. PMID: 37404872, PMCID: PMC10315001, DOI: 10.1159/000529536.Peer-Reviewed Original ResearchG protein-coupled receptorsPosttraumatic stress disorderEpigenomic findingsEpigenomic studiesEpigenomic profilesTranscriptomic modificationsEpigenetic studiesBrain transcriptomicsBiological pathwaysComplex multifactorial disorderGenesBrain tissueGene-environment interplayStress disorderSpeciesHuman postmortem samplesChemical synaptic transmissionSystematic literature searchEnvironmental factorsCurrent knowledge gapsPotential roleOrexin pathwayPathwayBrain alterationsPeripheral tissues
2019
Identification of gene ontology and pathways implicated in suicide behavior: Systematic review and enrichment analysis of GWAS studies
González‐Castro T, Tovilla‐Zárate C, Genis‐Mendoza A, Juárez‐Rojop I, Nicolini H, López‐Narváez M, Martínez‐Magaña J. Identification of gene ontology and pathways implicated in suicide behavior: Systematic review and enrichment analysis of GWAS studies. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2019, 180: 320-329. PMID: 31045331, DOI: 10.1002/ajmg.b.32731.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesBiological process gene ontologyGene OntologyProtein localizationPositive regulationKEGG pathwaysEnrichment analysisGenomes (KEGG) biological pathwaysHeterotypic cell-cell adhesionCell-cell adhesionGlucose importKyoto EncyclopediaGO analysisCardiomyopathy pathwaysGWAS studiesBiological pathwaysAssociation studiesGenesGenetic contributorsMultiple large-scale studiesEndopeptidase activityInsulin stimulusPathwayRegulationMuscle cell contraction