2020
Randomized controlled clinical study evaluating the efficacy and safety of intratumoral treatment of canine mast cell tumors with tigilanol tiglate (EBC‐46)
De Ridder TR, Campbell JE, Burke‐Schwarz C, Clegg D, Elliot EL, Geller S, Kozak W, Pittenger ST, Pruitt JB, Riehl J, White J, Wiest ML, Johannes CM, Morton J, Jones PD, Schmidt PF, Gordon V, Reddell P. Randomized controlled clinical study evaluating the efficacy and safety of intratumoral treatment of canine mast cell tumors with tigilanol tiglate (EBC‐46). Journal Of Veterinary Internal Medicine 2020, 35: 415-429. PMID: 32542733, PMCID: PMC7848366, DOI: 10.1111/jvim.15806.Peer-Reviewed Original ResearchConceptsMast cell tumorsComplete responseControl dogsAdverse eventsIntratumoral treatmentTigilanol tiglateCell tumorsClinical studiesTumor volumeModified Response Evaluation CriteriaTT treatmentOverall complete responseResponse Evaluation CriteriaCanine mast cell tumorsPhase 1Quality of lifeConcomitant medicationsTumor resolutionLocal treatmentTreatment responseSolid tumorsDogsTumorsTreatmentEfficacy
2019
Using Machine Learning Applied to Real-World Healthcare Data for Predictive Analytics: An Applied Example in Bariatric Surgery
Johnston SS, Morton JM, Kalsekar I, Ammann EM, Hsiao CW, Reps J. Using Machine Learning Applied to Real-World Healthcare Data for Predictive Analytics: An Applied Example in Bariatric Surgery. Value In Health 2019, 22: 580-586. PMID: 31104738, DOI: 10.1016/j.jval.2019.01.011.Peer-Reviewed Original ResearchConceptsLarge US healthcare claims databasesLaparoscopic metabolic surgeryHealthcare claims databasesType 2 diabetesStudy inclusion criteriaLogistic regression modelsDays postindexMedication cessationBariatric surgeryMetabolic surgeryT2D diagnosisCessation ratesPatient selectionMedication treatmentClaims databaseInclusion criteriaTreatment responseDiscriminative accuracyPatientsExternal validationSurgeryRegression modelsHealthcare dataTreatmentUseful predictive models
2018
Bariatric Surgery: Current State of Affairs
Blevins K, Azagury D, Morton J. Bariatric Surgery: Current State of Affairs. 2018, 17-20. DOI: 10.1007/978-3-319-93545-4_2.Peer-Reviewed Original Research