2021
The prognostic value of heart rate at discharge in acute decompensation of heart failure with reduced ejection fraction
Bahouth F, Elias A, Ghersin I, Khoury E, Bar O, Sholy H, Khoury J, Azzam Z. The prognostic value of heart rate at discharge in acute decompensation of heart failure with reduced ejection fraction. ESC Heart Failure 2021, 9: 585-594. PMID: 34821080, PMCID: PMC8788061, DOI: 10.1002/ehf2.13710.Peer-Reviewed Original ResearchConceptsReduced ejection fractionHeart rateHeart failureHazard ratioEjection fractionPrognostic valueTarget doseMortality rateChronic stable heart failureBeta-blocker dosageHeart failure settingAdjusted hazard ratioStable heart failureDay mortality rateSingle-center studyRetrospective observational studyYear mortality rateElevated heart rateLower heart rateHR 70Acute decompensationCause mortalityLaboratory variablesYear mortalityCox regression
2018
The association between treatment appropriateness according to EUCAST and CLSI breakpoints and mortality among patients with candidemia: a retrospective observational study
Ghanem-Zoubi N, Zorbavel D, Khoury J, Geffen Y, Qasum M, Predescu S, Paul M. The association between treatment appropriateness according to EUCAST and CLSI breakpoints and mortality among patients with candidemia: a retrospective observational study. European Journal Of Clinical Microbiology & Infectious Diseases 2018, 37: 2397-2404. PMID: 30284179, DOI: 10.1007/s10096-018-3389-1.Peer-Reviewed Original ResearchConceptsCLSI 2012Appropriate antifungal treatmentDefinitive treatmentOdds ratioAntifungal treatmentAntimicrobial Susceptibility Testing (EUCAST) breakpointsAppropriate definitive treatmentRetrospective observational studyAdjusted odds ratioAppropriate empirical treatmentBivariate logistic regressionCandidemia onsetCandidemia episodesEmpiric treatmentTreatment appropriatenessTertiary centerRetrospective studyCLSI breakpointsEmpirical treatmentObservational studyBreakpoint definitionPatientsResistance prevalenceMortalityLogistic regression