Quantitative Trait Locus Analysis Identifies Rat Genomic Regions Related to Amphetamine-Induced Locomotion and Gαi3 Levels in Nucleus Accumbens
Potenza MN, Brodkin ES, Yang BZ, Birnbaum SG, Nestler EJ, Gelernter J. Quantitative Trait Locus Analysis Identifies Rat Genomic Regions Related to Amphetamine-Induced Locomotion and Gαi3 Levels in Nucleus Accumbens. Neuropsychopharmacology 2008, 33: 2735-2746. PMID: 18216777, PMCID: PMC2818767, DOI: 10.1038/sj.npp.1301667.Peer-Reviewed Original ResearchMeSH KeywordsAmphetamineAnimalsGenomicsGTP-Binding Protein alpha Subunits, Gi-GoMaleMotor ActivityNucleus AccumbensQuantitative Trait LociRatsRats, Inbred F344Rats, Inbred LewConceptsQuantitative trait lociRobust quantitative trait lociGenomic regionsChromosome 2Quantitative trait locus (QTL) analysisG protein levelsCommon genetic mechanismQTL patternsTrait lociRat genomic regionsGenetic mechanismsChromosome 3Locus analysisChromosome 13Genetic factorsGαi3LociAmphetamine-Induced LocomotionBetter understandingLocomotionRegionAnimal modelsSignificant implicationsLevelsNovelty-induced locomotion