2019
Genome‐wide scan identifies opioid overdose risk locus close to MCOLN1
Cheng Z, Yang B, Zhou H, Nunez Y, Kranzler HR, Gelernter J. Genome‐wide scan identifies opioid overdose risk locus close to MCOLN1. Addiction Biology 2019, 25: e12811. PMID: 31362332, PMCID: PMC7485539, DOI: 10.1111/adb.12811.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesMucolipin-1Expression profilesGenome-wide significant signalsAssociation studiesPost-GWAS analysisWide association studyDrug repositioning analysisCation channel activityFunctional categoriesConnectivity Map databaseDrug targetsRisk genesGenesChannel activityPatatin-like phospholipaseNetwork analysisPNPLA6Significant signalEuropean Americans
2013
Genome-wide Association Study Identifies New Susceptibility Loci for Posttraumatic Stress Disorder
Xie P, Kranzler HR, Yang C, Zhao H, Farrer LA, Gelernter J. Genome-wide Association Study Identifies New Susceptibility Loci for Posttraumatic Stress Disorder. Biological Psychiatry 2013, 74: 656-663. PMID: 23726511, PMCID: PMC3810148, DOI: 10.1016/j.biopsych.2013.04.013.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsGenome-wide significanceFirst intronGenome-wide association study analysisGenome-wide association analysisNew susceptibility lociCandidate gene association studiesNew susceptibility genesCommon risk allelesGene association studiesChromosome 7p12Association studiesAssociation analysisSusceptibility lociSusceptibility genesGenetic variantsNucleotide polymorphismsIntronsTLL1GenesLociRisk allelesGenetic factorsSignificant signalEuropean Americans