2003
Sp1- and Krüppel-like transcription factors
Kaczynski J, Cook T, Urrutia R. Sp1- and Krüppel-like transcription factors. Genome Biology 2003, 4: 206. PMID: 12620113, PMCID: PMC151296, DOI: 10.1186/gb-2003-4-2-206.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAmino Acid SequenceAnimalsBinding SitesDNA-Binding ProteinsEvolution, MolecularGene Expression RegulationHumansKruppel-Like Transcription FactorsMolecular Sequence DataPhylogenyRepressor ProteinsSequence Homology, Amino AcidSp1 Transcription FactorTranscription FactorsTranscription, GeneticZinc FingersConceptsKruppel-like factorCellular functionsCell- and promoter-specific mannerSp1-like proteinsGC-rich promoterTranscriptional activation domainCellular transcription machineryZinc-finger proteinPromoter-specific mannerSp1-like factorsTranscription machineryHuman genomeTranscriptional regulationDNA bindingActivation domainAmino terminusGene expressionProteinCell proliferationNeoplastic transformationFamily membersPromoterExpressionGenomeRepressor
2001
A Conserved α-Helical Motif Mediates the Interaction of Sp1-Like Transcriptional Repressors with the Corepressor mSin3A
Zhang J, Moncrieffe M, Kaczynski J, Ellenrieder V, Prendergast F, Urrutia R. A Conserved α-Helical Motif Mediates the Interaction of Sp1-Like Transcriptional Repressors with the Corepressor mSin3A. Molecular And Cellular Biology 2001, 21: 5041-5049. PMID: 11438660, PMCID: PMC87230, DOI: 10.1128/mcb.21.15.5041-5049.2001.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid MotifsAmino Acid SequenceAnimalsApoptosis Regulatory ProteinsBlotting, WesternCell Cycle ProteinsCell DivisionCHO CellsCircular DichroismCricetinaeGenetic VectorsGlutathione TransferaseLuciferasesMolecular Sequence DataMutationPeptide BiosynthesisPlasmidsPrecipitin TestsProtein BindingProtein BiosynthesisProtein Structure, TertiaryRecombinant Fusion ProteinsRepressor ProteinsSequence Homology, Amino AcidSin3 Histone Deacetylase and Corepressor ComplexSp1 Transcription FactorTranscription, GeneticTransforming Growth Factor betaZinc FingersConceptsSp1-like proteinsRepress transcriptionDeacetylase complexRepression motifTranscriptional repressionSin3 histone deacetylase complexBind GC-rich sequencesMechanism of transcriptional repressionSp1-like transcription factorsMSin3A-histone deacetylase complexGC-rich sequencesMammalian cell homeostasisCorepressor mSin3ARepression domainTranscriptional repressorA-helicesMSin3ATranscription factorsTIEG2Antiproliferative functionCell homeostasisMotifTranscriptionRepressionProtein