1985
Transfer RNA is an essential component of the ubiquitin- and ATP-dependent proteolytic system.
Ciechanover A, Wolin SL, Steitz JA, Lodish HF. Transfer RNA is an essential component of the ubiquitin- and ATP-dependent proteolytic system. Proceedings Of The National Academy Of Sciences Of The United States Of America 1985, 82: 1341-1345. PMID: 2983338, PMCID: PMC397256, DOI: 10.1073/pnas.82.5.1341.Peer-Reviewed Original ResearchConceptsATP-dependent proteolytic systemProteolytic systemATP-dependent degradationATP-requiring reactionATP-dependent pathwayProteolytic activityProgression of cellsProtein substratesTransfer RNAGene activationMammalian cellsUncharged tRNAReticulocyte extractsProtein degradationTRNA fractionReticulocyte systemMouse cellsCell cycleUbiquitinEssential componentRNAGel electrophoresisTRNAConjugated proteinsAutoimmune sera
1982
Precursor molecules of both human 5S ribosomal RNA and transfer RNAs are bound by a cellular protein reactive with anti-La Lupus antibodies
Rinke J, Steitz J. Precursor molecules of both human 5S ribosomal RNA and transfer RNAs are bound by a cellular protein reactive with anti-La Lupus antibodies. Cell 1982, 29: 149-159. PMID: 7105180, DOI: 10.1016/0092-8674(82)90099-x.Peer-Reviewed Original ResearchConceptsRRNA moleculesLa proteinLa RNAsPrecursor formNuclear transcription systemUninfected mammalian cellsPulse-chase experimentsSmall RNAsSmall ribonucleoproteinPrecursor moleculesTransfer RNAMammalian cellsRibosomal RNATRNA precursorsCertain tRNAsSpecific tRNAsRNA transcriptsTranscription systemU residuesCell extractsMature sizeHeLa cellsRNAEssential roleProtein
1981
Ro Small Cytoplasmic Ribonucleoproteins Are a Subclass of La Ribonucleoproteins: Further Characterization of the Ro and La Small Ribonucleoproteins from Uninfected Mammalian Cells
Hendrick J, Wolin S, Rinke J, Lerner M, Steitz J. Ro Small Cytoplasmic Ribonucleoproteins Are a Subclass of La Ribonucleoproteins: Further Characterization of the Ro and La Small Ribonucleoproteins from Uninfected Mammalian Cells. Molecular And Cellular Biology 1981, 1: 1138-1149. DOI: 10.1128/mcb.1.12.1138-1149.1981.Peer-Reviewed Original ResearchLa RNAsRNA polymerase III transcriptionLa ribonucleoproteinsHuman cellsPolymerase III transcriptionRNA polymerase IIINuclear transcription systemIII transcriptionSmall ribonucleoproteinsPolymerase IIITransfer RNACytoplasmic ribonucleoproteinRNA-like moleculesRNA componentRNA moleculesTranscription systemRo ribonucleoproteinsRibonucleoproteinMouse cellsReconstitution experimentsRNAInternal modificationCell cytoplasmTranscriptionCellsRo Small Cytoplasmic Ribonucleoproteins Are a Subclass of La Ribonucleoproteins: Further Characterization of the Ro and La Small Ribonucleoproteins from Uninfected Mammalian Cells
Hendrick J, Wolin S, Rinke J, Lerner M, Steitz J. Ro Small Cytoplasmic Ribonucleoproteins Are a Subclass of La Ribonucleoproteins: Further Characterization of the Ro and La Small Ribonucleoproteins from Uninfected Mammalian Cells. Molecular And Cellular Biology 1981, 1: 1138-1149. DOI: 10.1128/mcb.1.12.1138-1149.1981.Peer-Reviewed Original ResearchLa RNAsHuman cellsRNA polymerase III transcriptsNuclear transcription systemRNA polymerase IIIUninfected mammalian cellsPolymerase III transcriptsSmall cytoplasmic ribonucleoproteinsDifferent RNA moleculesSmall ribonucleic acidsProtein complexesSmall ribonucleoproteinTransfer RNAMammalian cellsRo RNPsPolymerase IIIRNA componentCytoplasmic ribonucleoproteinRNA moleculesTranscription systemMouse cellsReconstitution experimentsLa ribonucleoproteinsRibonucleoproteinRNARo small cytoplasmic ribonucleoproteins are a subclass of La ribonucleoproteins: further characterization of the Ro and La small ribonucleoproteins from uninfected mammalian cells.
Hendrick JP, Wolin SL, Rinke J, Lerner MR, Steitz JA. Ro small cytoplasmic ribonucleoproteins are a subclass of La ribonucleoproteins: further characterization of the Ro and La small ribonucleoproteins from uninfected mammalian cells. Molecular And Cellular Biology 1981, 1: 1138-1149. PMID: 6180298, PMCID: PMC369740, DOI: 10.1128/mcb.1.12.1138.Peer-Reviewed Original ResearchConceptsLa RNAsHuman cellsRNA polymerase III transcriptsNuclear transcription systemRNA polymerase IIIUninfected mammalian cellsPolymerase III transcriptsSmall cytoplasmic ribonucleoproteinsDifferent RNA moleculesSmall ribonucleic acidsProtein complexesSmall ribonucleoproteinTransfer RNAMammalian cellsRo RNPsPolymerase IIIRNA componentCytoplasmic ribonucleoproteinRNA moleculesTranscription systemMouse cellsReconstitution experimentsRNARNA-like moleculesCell cytoplasm
1977
The nucleotide sequence of a major glycine transfer RNA from the posterior silk gland of Bombyx mori L.
Zúñiga M, Steitz J. The nucleotide sequence of a major glycine transfer RNA from the posterior silk gland of Bombyx mori L. Nucleic Acids Research 1977, 4: 4175-4196. PMID: 414206, PMCID: PMC343233, DOI: 10.1093/nar/4.12.4175.Peer-Reviewed Original Research