2022
Survival Probability and Survival Benefit Associated With Primary Prevention Implantable Cardioverter‐Defibrillator Generator Changes
Bilchick KC, Wang Y, Curtis JP, Shadman R, Dardas TF, Anand I, Lund LH, Dahlström U, Sartipy U, Levy WC. Survival Probability and Survival Benefit Associated With Primary Prevention Implantable Cardioverter‐Defibrillator Generator Changes. Journal Of The American Heart Association 2022, 11: e023743. PMID: 35766293, PMCID: PMC9333379, DOI: 10.1161/jaha.121.023743.Peer-Reviewed Original ResearchConceptsSeattle Heart Failure ModelHeart failure modelHeart failure patientsResynchronization therapyGenerator changeSurvival benefitWorse survivalFailure patientsNational Cardiovascular Data Registry ICD RegistryGC survivalSurvival Benefit AssociatedPrimary prevention indicationVentricular ejection fractionAnnual mortalityICD therapyConclusions PatientsPrevention indicationEjection fractionICD RegistryImproved survivalPrimary preventionPatient deathGreater effect sizeLVEFPatients
2021
Longitudinal Outcomes Associated With Non-Evidence-Based Implantable Cardioverter-Defibrillators Among Medicare Beneficiaries (From the National Cardiovascular Data Registry)
Daimee UA, Aslam F, Parzynski CS, Desai NR, Curtis JP. Longitudinal Outcomes Associated With Non-Evidence-Based Implantable Cardioverter-Defibrillators Among Medicare Beneficiaries (From the National Cardiovascular Data Registry). The American Journal Of Cardiology 2021, 155: 64-71. PMID: 34315569, DOI: 10.1016/j.amjcard.2021.06.020.Peer-Reviewed Original ResearchConceptsPrimary prevention ICD implantationRisk of mortalityICD implantationHeart failureICD RegistryMortality riskNational Cardiovascular Data Registry ICD RegistryPivotal randomized clinical trialsHospital adverse eventsSevere heart failureRecent myocardial infarctionCause hospital readmissionRandomized clinical trialsSimilar mortality riskLongitudinal outcomesImplantable cardioverter defibrillatorGreater mortality riskCause hospitalizationCause mortalityCoronary revascularizationAdverse eventsHospital readmissionICD recipientsDevice implantationPrimary preventionImpact of insurance status on ICD implantation practice patterns: Insights from the NCDR ICD registry
Ahmed I, Merchant FM, Curtis JP, Parzynski CS, Lampert R. Impact of insurance status on ICD implantation practice patterns: Insights from the NCDR ICD registry. American Heart Journal 2021, 235: 44-53. PMID: 33503408, DOI: 10.1016/j.ahj.2021.01.016.Peer-Reviewed Original ResearchConceptsOptimal medical therapyInsurance statusNCDR ICD RegistryMedical therapyComplication rateICD RegistryUninsured patientsCardiac resynchronization therapy defibrillatorPrivate insurancePropensity-weighted analysisSingle-chamber devicesPrimary preventionMean ageICD implantsPractice patternsTreatment weightingImplantation practicePatientsInverse probabilityTherapyInsurance coverageFurther studiesRegistryMedicareStatus
2020
Periprocedural Risk and Survival Associated With Implantable Cardioverter-Defibrillator Placement in Older Patients With Advanced Heart Failure
Fudim M, Ali-Ahmed F, Parzynski CS, Ambrosy AP, Friedman DJ, Pokorney SD, Curtis JP, Fonarow GC, Masoudi FA, Hernandez AF, Al-Khatib SM. Periprocedural Risk and Survival Associated With Implantable Cardioverter-Defibrillator Placement in Older Patients With Advanced Heart Failure. JAMA Cardiology 2020, 5: 643-651. PMID: 32211811, PMCID: PMC7097837, DOI: 10.1001/jamacardio.2020.0391.Peer-Reviewed Original ResearchConceptsAdvanced heart failureAdvanced HF populationHeart transplant listingPeriprocedural complication rateHeart failureSudden cardiac deathComparator groupVentricular assist deviceInotrope useTransplant listingCardiac deathComplication rateHF populationPrimary preventionCardiac arrestNew York Heart Association class IV symptomsNational Cardiovascular Data Registry ICD RegistryAssist deviceLeft ventricular ejection fractionImplantable cardioverter-defibrillator placementAdvanced HF groupClass IV symptomsFirst-time ICDLeft ventricular assist deviceNYHA class II
2018
Periprocedural Risk and Survival after ICD Placement in Patients with Advanced Heart Failure
Fudim M, Parzynski C, Pokorney S, Ambrosy A, Friedman D, Curtis J, Fonarow G, Masoudi F, Hernandez A, Al-Khatib S. Periprocedural Risk and Survival after ICD Placement in Patients with Advanced Heart Failure. Journal Of Cardiac Failure 2018, 24: s63. DOI: 10.1016/j.cardfail.2018.07.275.Peer-Reviewed Original ResearchAdvanced heart failureOrthotopic heart transplantNYHA class IV symptomsClass IV symptomsPrimary prevention ICDsPeriprocedural complication rateHeart failureInitial ICDHF patientsComplication rateICD RegistryPrimary preventionCardiac arrestNational Cardiovascular Data Registry ICD RegistryDiagnosis of HFCause survival ratesICD/CRTNYHA class IVAdvanced HF patientsIschemic heart diseaseAdditional prospective researchSudden cardiac deathCRT-D devicesSudden cardiac arrestCox hazard modelAssociation of the US Department of Justice Investigation of Implantable Cardioverter-Defibrillators and Devices Not Meeting the Medicare National Coverage Determination, 2007-2015
Desai NR, Bourdillon PM, Parzynski CS, Brindis RG, Spatz ES, Masters C, Minges KE, Peterson P, Masoudi FA, Oetgen WJ, Buxton A, Zipes DP, Curtis JP. Association of the US Department of Justice Investigation of Implantable Cardioverter-Defibrillators and Devices Not Meeting the Medicare National Coverage Determination, 2007-2015. JAMA 2018, 320: 63-71. PMID: 29971398, PMCID: PMC6583049, DOI: 10.1001/jama.2018.8151.Peer-Reviewed Original ResearchConceptsPrimary prevention ICDsNon-Medicare beneficiariesAbsolute decreaseNational Cardiovascular Data Registry ICD RegistrySerial cross-sectional analysisStudy periodImplantable cardioverter defibrillatorRelative decreaseCross-sectional analysisProportion of devicesInitial ICDICD RegistryPrimary preventionCardioverter defibrillatorMAIN OUTCOMEMedicare beneficiariesUS hospitalsHospital groupHospitalICDMore rapid decreasesModest decreaseDepartmentMedicareUS Department
2015
Defibrillator implantations for primary prevention in the United States: Inappropriate care or inadequate documentation: Insights from the National Cardiovascular Data ICD Registry
Kaiser DW, Tsai V, Heidenreich PA, Goldstein MK, Wang Y, Curtis J, Turakhia MP, Registry C. Defibrillator implantations for primary prevention in the United States: Inappropriate care or inadequate documentation: Insights from the National Cardiovascular Data ICD Registry. Heart Rhythm 2015, 12: 2086-2093. PMID: 25982720, PMCID: PMC4770888, DOI: 10.1016/j.hrthm.2015.05.010.Peer-Reviewed Original ResearchConceptsMulticenter Unsustained Tachycardia TrialMulticenter Automatic Defibrillator Implantation TrialICD RegistryPrimary preventionICD implantationInclusion criteriaNational Cardiovascular Data Registry ICD RegistryMultivariate analysisImplantable cardioverter defibrillator implantationAtrioventricular conduction diseaseFirst-time ICDPrimary prevention ICDsPrior cardiac transplantationHeart Failure TrialPrimary prevention trialsProportion of patientsCardioverter-defibrillator implantationAppropriate use criteriaSudden cardiac deathCardiac transplantationDefibrillator implantationMADIT-IIPatient characteristicsYounger patientsCardiac deathGender and outcomes after primary prevention implantable cardioverter-defibrillator implantation: Findings from the National Cardiovascular Data Registry (NCDR)
Russo AM, Daugherty SL, Masoudi FA, Wang Y, Curtis J, Lampert R. Gender and outcomes after primary prevention implantable cardioverter-defibrillator implantation: Findings from the National Cardiovascular Data Registry (NCDR). American Heart Journal 2015, 170: 330-338. PMID: 26299231, PMCID: PMC4768728, DOI: 10.1016/j.ahj.2015.02.025.Peer-Reviewed Original ResearchConceptsNational Cardiovascular Data RegistryPrimary preventionHF readmissionCause readmissionHospital dischargeICD implantationHeart failurePrimary prevention implantable cardioverter-defibrillator (ICD) implantationDual-chamber ICD implantationImplantable cardioverter defibrillator implantationPatients 65 yearsAdvanced heart failureProcedure-related complicationsCardioverter-defibrillator implantationDevice-related complicationsSudden cardiac deathHigh-risk individualsDual-chamber ICDGreater comorbidityBaseline characteristicsOlder patientsCardiac deathProcedural complicationsWorse outcomesClinical trialsA validated risk model for 1-year mortality after primary prevention implantable cardioverter defibrillator placement
Heidenreich PA, Tsai V, Curtis J, Wang Y, Turakhia MP, Masoudi FA, Varosy PD, Goldstein MK. A validated risk model for 1-year mortality after primary prevention implantable cardioverter defibrillator placement. American Heart Journal 2015, 170: 281-289.e2. PMID: 26299225, DOI: 10.1016/j.ahj.2014.12.013.Peer-Reviewed Original ResearchConceptsOne-year mortalityImplantable cardioverter defibrillatorRisk factorsHeart failurePrimary preventionMortality riskRisk scorePrimary prevention implantable cardioverter-defibrillator placementB-type natriuretic peptide valuesImplantable cardioverter-defibrillator placementCardiovascular Disease RegistryPrimary prevention populationNatriuretic peptide valuesChronic lung diseaseSystolic blood pressureSimilar risk factorsBlood urea nitrogenPg/mLLogistic regression modelsPrevention populationICD therapyICD implantationBlood pressureICD RegistryICD placement
2014
Implant and Clinical Characteristics for Pediatric and Congenital Heart Patients in the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry
Jordan CP, Freedenberg V, Wang Y, Curtis JP, Gleva MJ, Berul CI. Implant and Clinical Characteristics for Pediatric and Congenital Heart Patients in the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry. Circulation Arrhythmia And Electrophysiology 2014, 7: 1092-1100. PMID: 25287482, DOI: 10.1161/circep.114.001841.Peer-Reviewed Original ResearchConceptsNew York Heart Association classPrimary preventionSecondary preventionPediatric patientsAssociation classLEAD patientsGreat vesselsNational Cardiovascular Data Registry Implantable Cardioverter Defibrillator RegistryHigher New York Heart Association classImplantable Cardioverter-Defibrillator RegistryImplantable cardioverter defibrillator implantationNational Cardiovascular Data RegistryImplantable cardioverter-defibrillator indicationsImplantable cardioverter-defibrillator (ICD) proceduresCongenital heart patientsCardioverter-defibrillator implantationStructural heart diseaseHigh rateLead implantsOverall registryVentricle patientsClinical characteristicsDefibrillator implantationCHD typesCommon ventricleTemporal Trends in Patient Characteristics and Outcomes Among Medicare Beneficiaries Undergoing Primary Prevention Implantable Cardioverter-Defibrillator Placement in the United States, 2006–2010
Borne RT, Peterson PN, Greenlee R, Heidenreich PA, Wang Y, Curtis JP, Tzou WS, Varosy PD, Kremers MS, Masoudi FA. Temporal Trends in Patient Characteristics and Outcomes Among Medicare Beneficiaries Undergoing Primary Prevention Implantable Cardioverter-Defibrillator Placement in the United States, 2006–2010. Circulation 2014, 130: 845-853. PMID: 25095884, DOI: 10.1161/circulationaha.114.008653.Peer-Reviewed Original ResearchConceptsPrimary prevention ICD implantationDevice-related complicationsPatient characteristicsICD implantationICD RegistryNational Cardiovascular Data Registry ICD RegistryPrimary prevention implantable cardioverter-defibrillator placementConcomitant cardiac resynchronization therapyLeft ventricular ejection fractionImplantable cardioverter-defibrillator placementMultivariable hierarchical logistic regressionCardiac resynchronization therapy devicesCardiac resynchronization therapyVentricular ejection fractionResynchronization therapy devicesCommunity practice settingsSingle-lead deviceHierarchical logistic regressionClinical characteristicsOlder patientsEjection fractionResynchronization therapyPrimary preventionPatient populationHospital characteristics
2013
Association of Single- vs Dual-Chamber ICDs With Mortality, Readmissions, and Complications Among Patients Receiving an ICD for Primary Prevention
Peterson PN, Varosy PD, Heidenreich PA, Wang Y, Dewland TA, Curtis JP, Go AS, Greenlee RT, Magid DJ, Normand SL, Masoudi FA. Association of Single- vs Dual-Chamber ICDs With Mortality, Readmissions, and Complications Among Patients Receiving an ICD for Primary Prevention. JAMA 2013, 309: 2025-2034. PMID: 23677314, PMCID: PMC3752924, DOI: 10.1001/jama.2013.4982.Peer-Reviewed Original ResearchConceptsDual-chamber ICDSingle-chamber devicesDevice-related complicationsPrimary preventionDual-chamber devicesICD RegistryNational Cardiovascular Data Registry ICD RegistryPropensity-matched cohortRetrospective cohort studyHeart failure readmissionRate of complicationsSudden cardiac deathMedicaid Services feePropensity-score matchingCause hospitalizationCause readmissionCohort studyHospital factorsCardiac deathHeart failureHospitalization outcomesRandomized trialsChamber ICDMAIN OUTCOMEHigh risk
2012
Variation in Use of Dual-Chamber Implantable Cardioverter-Defibrillators: Results From the National Cardiovascular Data Registry
Matlock DD, Peterson PN, Wang Y, Curtis JP, Reynolds MR, Varosy PD, Masoudi FA. Variation in Use of Dual-Chamber Implantable Cardioverter-Defibrillators: Results From the National Cardiovascular Data Registry. JAMA Internal Medicine 2012, 172: 634-641. PMID: 22529229, PMCID: PMC8317619, DOI: 10.1001/archinternmed.2012.394.Peer-Reviewed Original ResearchMeSH KeywordsAgedCluster AnalysisComorbidityCross-Sectional StudiesDeath, Sudden, CardiacDefibrillators, ImplantableEquipment DesignFemaleHospitalsHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisNew EnglandOdds RatioPacemaker, ArtificialPacific StatesPredictive Value of TestsPrimary PreventionRegistriesConceptsDual-chamber ICDDual-chamber devicesPrimary preventionDual-Chamber Implantable CardioverterMultivariate hierarchical logistic regressionNational Cardiovascular Data RegistrySingle-chamber ICDHospital-level variationStrong independent predictorSudden cardiac deathCross-sectional studyHealth care providersHierarchical logistic regressionPacing indicationCardiac deathHospital clusteringIndependent predictorsPatient factorsPhysician factorsHospital ratesImplantable cardioverterCare providersIdentical patientsCurrent evidenceData registry
2011
Age Differences in Primary Prevention Implantable Cardioverter‐Defibrillator Use in U.S. Individuals
Tsai V, Goldstein MK, Hsia HH, Wang Y, Curtis J, Heidenreich PA, Registry O. Age Differences in Primary Prevention Implantable Cardioverter‐Defibrillator Use in U.S. Individuals. Journal Of The American Geriatrics Society 2011, 59: 1589-1595. PMID: 21883101, DOI: 10.1111/j.1532-5415.2011.03542.x.Peer-Reviewed Original ResearchConceptsICD RegistryICD useNonarrhythmic deathHigh riskImplantable cardioverter-defibrillator (ICD) useHigh comorbid burdenPrior myocardial infarctionRisk of deathHigh-risk individualsRisk stratification systemOlder U.S. adultsYounger age groupsComorbid burdenICD implantationEjection fractionICD recipientsPrimary preventionRetrospective studyMyocardial infarctionMortality riskLower riskAge groupsU.S. adultsYounger groupOlder adultsNon–Evidence-Based ICD Implantations in the United States
Al-Khatib SM, Hellkamp A, Curtis J, Mark D, Peterson E, Sanders GD, Heidenreich PA, Hernandez AF, Curtis LH, Hammill S. Non–Evidence-Based ICD Implantations in the United States. JAMA 2011, 305: 43-49. PMID: 21205965, PMCID: PMC3432303, DOI: 10.1001/jama.2010.1915.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiologyCohort StudiesCoronary Artery BypassDeath, Sudden, CardiacDefibrillators, ImplantableEvidence-Based MedicineFemaleGuideline AdherenceHeart FailureHospital MortalityHumansMaleMiddle AgedMyocardial InfarctionPatient SelectionPractice Patterns, Physicians'Primary PreventionRegistriesRetrospective StudiesTreatment OutcomeUnited StatesConceptsICD implantsHospital outcomesNational Cardiovascular Data Registry ICD RegistryCoronary artery bypass graft surgerySevere heart failure symptomsArtery bypass graft surgeryBypass graft surgeryHeart failure symptomsRetrospective cohort studyYear of procedureEvidence-based criteriaGraft surgeryHospital deathCohort studyICD implantationHeart failurePostprocedure complicationsPrimary preventionMyocardial infarctionRecent diagnosisFailure symptomsPhysician specialtyPractice guidelinesMAIN OUTCOMEHigh risk
2010
Regional Variation in the Use of Implantable Cardioverter-Defibrillators for Primary Prevention
Matlock DD, Peterson PN, Heidenreich PA, Lucas FL, Malenka DJ, Wang Y, Curtis JP, Kutner JS, Fisher ES, Masoudi FA. Regional Variation in the Use of Implantable Cardioverter-Defibrillators for Primary Prevention. Circulation Cardiovascular Quality And Outcomes 2010, 4: 114-121. PMID: 21139094, DOI: 10.1161/circoutcomes.110.958264.Peer-Reviewed Original ResearchConceptsPrimary prevention ICDsProportion of patientsTrial inclusion criteriaInclusion criteriaPrimary preventionTrial criteriaPhysician supplyNational Cardiovascular Data RegistryImplantable cardioverter defibrillatorHospital referral regionsRace-adjusted ratesCross-sectional analysisICD implantationICD placementCardioverter defibrillatorReferral regionsData registryPotential overusePatientsICDDeath variesRate ratioService populationGeographic variationRegional variation
2009
Clinical characteristics and in-hospital outcome of patients with end-stage renal disease on dialysis referred for implantable cardioverter-defibrillator implantation
Aggarwal A, Wang Y, Rumsfeld JS, Curtis JP, Heidenreich PA, Registry C. Clinical characteristics and in-hospital outcome of patients with end-stage renal disease on dialysis referred for implantable cardioverter-defibrillator implantation. Heart Rhythm 2009, 6: 1565-1571. PMID: 19879533, DOI: 10.1016/j.hrthm.2009.08.006.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillator implantationESRD patientsCardioverter-defibrillator implantationICD implantationHospital complicationsTotal complicationsHospital stayPrimary preventionEnd-stage renal disease patientsEnd-stage renal diseaseComorbid medical conditionsRenal disease patientsHigh rateERSD patientsHospital mortalityHospital outcomesClinical characteristicsAngiotensin inhibitorsClinical profileICD RegistryMajor complicationsPrimary outcomeRenal diseaseMultivariable analysisDevice implantationUse of implantable cardioverter defibrillators for primary prevention in the community: Do women and men equally meet trial enrollment criteria?
Daugherty SL, Peterson PN, Wang Y, Curtis JP, Heidenreich PA, Lindenfeld J, Vidaillet HJ, Masoudi FA, behalf of the NCDR O. Use of implantable cardioverter defibrillators for primary prevention in the community: Do women and men equally meet trial enrollment criteria? American Heart Journal 2009, 158: 224-229. PMID: 19619698, DOI: 10.1016/j.ahj.2009.05.018.Peer-Reviewed Original ResearchConceptsTrial enrollment criteriaPrimary prevention ICD implantationEnrollment criteriaICD implantationMADIT-IIMultivariable analysisPrimary preventionTrial criteriaNational Cardiovascular Data Registry ICD RegistryPrimary prevention ICD placementImplantable cardioverter defibrillator implantationSCD-HeFT trialsCardioverter-defibrillator implantationSudden cardiac deathImplantable cardioverter defibrillatorDefibrillator implantationSCD-HeFTYounger patientsCardiac deathICD RegistryICD placementNational cohortCardioverter defibrillatorOlder womenPatients