2017
Ghrelin is Supressed by Intravenous Alcohol and is Related to Stimulant and Sedative Effects of Alcohol
Ralevski E, Horvath TL, Shanabrough M, Hayden R, Newcomb J, Petrakis I. Ghrelin is Supressed by Intravenous Alcohol and is Related to Stimulant and Sedative Effects of Alcohol. Alcohol And Alcoholism 2017, 52: 431-438. PMID: 28481974, DOI: 10.1093/alcalc/agx022.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntravenousAdultBreath TestsCentral Nervous System StimulantsDose-Response Relationship, DrugEthanolFastingFemaleGhrelinHealthy VolunteersHumansHypnotics and SedativesMaleYoung AdultConceptsGhrelin levelsDoses of alcoholHealthy social drinkersSubjective effectsTG levelsAlcohol infusionSedative effectsLow doseHigh doseOral alcohol administrationIntravenous alcohol infusionFeeding-related peptidesSocial drinkersAlcohol administrationIntravenous alcoholOral alcoholGhrelinPercent changeInfusionRewarding propertiesBehavioral effectsAlcohol effectsDoseTime pointsSignificant predictors
2016
Effect of Intravenous Ethanol on Capsaicin‐Induced Hyperalgesia in Human Subjects
Arout CA, Perrino AC, Ralevski E, Acampora G, Koretski J, Limoncelli D, Newcomb J, Petrakis IL. Effect of Intravenous Ethanol on Capsaicin‐Induced Hyperalgesia in Human Subjects. Alcohol Clinical And Experimental Research 2016, 40: 1425-1429. PMID: 27218476, PMCID: PMC4930397, DOI: 10.1111/acer.13095.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntravenousAdultAffectBreath TestsCapsaicinDose-Response Relationship, DrugDouble-Blind MethodEthanolFemaleHumansHyperalgesiaMaleYoung AdultConceptsCapsaicin-induced hyperalgesiaVon Frey techniqueTime pointsArea of hyperalgesiaIntradermal capsaicin injectionExperimental pain paradigmVisual analog scaleAdditional outcome measuresImportant clinical implicationsTest dayETOH infusionHyperalgesia areasIntravenous EtOHAntihyperalgesic effectCentral sensitizationPrimary outcomeCapsaicin injectionChronic painPain processingAnalog scaleBreath alcohol concentrationIntravenous ethanolPain medicineHyperalgesiaOutcome measures
2013
Effects of Family History of Alcohol Dependence on the Subjective Response to Alcohol Using the Intravenous Alcohol Clamp
Kerfoot K, Pittman B, Ralevski E, Limoncelli D, Koretski J, Newcomb J, Arias AJ, Petrakis IL. Effects of Family History of Alcohol Dependence on the Subjective Response to Alcohol Using the Intravenous Alcohol Clamp. Alcohol Clinical And Experimental Research 2013, 37: 2011-2018. PMID: 23895557, PMCID: PMC3971638, DOI: 10.1111/acer.12199.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcoholismCognitionDose-Response Relationship, DrugDouble-Blind MethodEthanolFemaleHumansMalePlacebosPsychomotor PerformanceReaction TimeYoung AdultConceptsAlcohol use disorderSubjective responsesBiphasic Alcohol Effects ScaleSubjective effectsUse disordersEffects of FHSimilar dose-related effectsTest dayCognitive effectsCognitive functionHigh-dose alcoholMeasure of coordinationSeparate test daysFamily historySubjective measuresHigh-dose EtOHImpairment of coordinationAlcohol challengeAlcohol dependenceEffects ScaleDouble-blind conditionsLow-dose ethanolAlcohol administrationVisual analog scaleIndividuals