2017
Ghrelin is Supressed by Intravenous Alcohol and is Related to Stimulant and Sedative Effects of Alcohol
Ralevski E, Horvath TL, Shanabrough M, Hayden R, Newcomb J, Petrakis I. Ghrelin is Supressed by Intravenous Alcohol and is Related to Stimulant and Sedative Effects of Alcohol. Alcohol And Alcoholism 2017, 52: 431-438. PMID: 28481974, DOI: 10.1093/alcalc/agx022.Peer-Reviewed Original ResearchConceptsGhrelin levelsDoses of alcoholHealthy social drinkersSubjective effectsTG levelsAlcohol infusionSedative effectsLow doseHigh doseOral alcohol administrationIntravenous alcohol infusionFeeding-related peptidesSocial drinkersAlcohol administrationIntravenous alcoholOral alcoholGhrelinPercent changeInfusionRewarding propertiesBehavioral effectsAlcohol effectsDoseTime pointsSignificant predictors
2016
Effect of Intravenous Ethanol on Capsaicin‐Induced Hyperalgesia in Human Subjects
Arout CA, Perrino AC, Ralevski E, Acampora G, Koretski J, Limoncelli D, Newcomb J, Petrakis IL. Effect of Intravenous Ethanol on Capsaicin‐Induced Hyperalgesia in Human Subjects. Alcohol Clinical And Experimental Research 2016, 40: 1425-1429. PMID: 27218476, PMCID: PMC4930397, DOI: 10.1111/acer.13095.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntravenousAdultAffectBreath TestsCapsaicinDose-Response Relationship, DrugDouble-Blind MethodEthanolFemaleHumansHyperalgesiaMaleYoung AdultConceptsCapsaicin-induced hyperalgesiaVon Frey techniqueTime pointsArea of hyperalgesiaIntradermal capsaicin injectionExperimental pain paradigmVisual analog scaleAdditional outcome measuresImportant clinical implicationsTest dayETOH infusionHyperalgesia areasIntravenous EtOHAntihyperalgesic effectCentral sensitizationPrimary outcomeCapsaicin injectionChronic painPain processingAnalog scaleBreath alcohol concentrationIntravenous ethanolPain medicineHyperalgesiaOutcome measures