2020
Thiopental Does Not Produce Hyperalgesia: A Laboratory Study Using Two Human Experimental Pain Models
Arout CA, Petrakis IL, Ralevski E, Acampora G, Koretski J, DeNegre D, Newcomb J, Perrino AC. Thiopental Does Not Produce Hyperalgesia: A Laboratory Study Using Two Human Experimental Pain Models. Pain Medicine 2020, 21: 2823-2829. PMID: 32249311, PMCID: PMC8453625, DOI: 10.1093/pm/pnaa037.Peer-Reviewed Original ResearchConceptsArea of hyperalgesiaExperimental pain modelsCapsaicin conditionPain modelPain thresholdElectrical stimulationPercent changeHuman experimental pain modelsEffects of thiopentalVon Frey techniqueMcGill Pain QuestionnaireExperimental pain paradigmNoxious electrical stimulationSignificant differencesIntradermal capsaicinPain interpretationThiopental effectPain QuestionnaireBarbiturate administrationHyperalgesiaThiopental infusionHuman studiesPain paradigmPain toleranceElectrical stimulation currents
2017
Ghrelin is Supressed by Intravenous Alcohol and is Related to Stimulant and Sedative Effects of Alcohol
Ralevski E, Horvath TL, Shanabrough M, Hayden R, Newcomb J, Petrakis I. Ghrelin is Supressed by Intravenous Alcohol and is Related to Stimulant and Sedative Effects of Alcohol. Alcohol And Alcoholism 2017, 52: 431-438. PMID: 28481974, DOI: 10.1093/alcalc/agx022.Peer-Reviewed Original ResearchConceptsGhrelin levelsDoses of alcoholHealthy social drinkersSubjective effectsTG levelsAlcohol infusionSedative effectsLow doseHigh doseOral alcohol administrationIntravenous alcohol infusionFeeding-related peptidesSocial drinkersAlcohol administrationIntravenous alcoholOral alcoholGhrelinPercent changeInfusionRewarding propertiesBehavioral effectsAlcohol effectsDoseTime pointsSignificant predictors