2020
Neural responsivity to social rewards in autistic female youth
Lawrence KE, Hernandez LM, Eilbott J, Jack A, Aylward E, Gaab N, Van Horn JD, Bernier RA, Geschwind DH, McPartland JC, Nelson CA, Webb SJ, Pelphrey KA, Bookheimer SY, Dapretto M. Neural responsivity to social rewards in autistic female youth. Translational Psychiatry 2020, 10: 178. PMID: 32488083, PMCID: PMC7266816, DOI: 10.1038/s41398-020-0824-8.Peer-Reviewed Original ResearchConceptsImplicit learning taskSocial rewardsAutistic girlsAutistic boysLearning taskSocial reward processingSocial reward systemFemale youthPrevious neuroimaging studiesFunctional magnetic resonanceLateral frontal cortexSocial stimuliNeural responsivityReward processingSocial motivationRewarding stimuliAnterior insulaGreater activityNeural activationNeuroimaging studiesPotential sex differencesRewarding natureSalience detectionAutistic femalesBehavioral evidence
2019
Social motivation in autism: Gaps and directions for measurement of a putative core construct
Keifer C, Dichter G, McPartland J, Lerner M. Social motivation in autism: Gaps and directions for measurement of a putative core construct. Behavioral And Brain Sciences 2019, 42: e95. DOI: 10.1017/s0140525x18002418.Peer-Reviewed Original ResearchSocial motivation
2012
Neural Mechanisms of Improvements in Social Motivation After Pivotal Response Treatment: Two Case Studies
Voos AC, Pelphrey KA, Tirrell J, Bolling DZ, Wyk B, Kaiser MD, McPartland JC, Volkmar FR, Ventola P. Neural Mechanisms of Improvements in Social Motivation After Pivotal Response Treatment: Two Case Studies. Journal Of Autism And Developmental Disorders 2012, 43: 1-10. PMID: 23104615, PMCID: PMC4999079, DOI: 10.1007/s10803-012-1683-9.Peer-Reviewed Original ResearchConceptsPivotal Response TreatmentAutism spectrum disorderSocial stimuliResponse treatmentFunctional magnetic resonance imagingYoung childrenNeural correlatesSocial motivationSocial skillsSocial perceptionNeural mechanismsNeural responsesBehavioral measuresSpectrum disorderSocial communicationBehavioral treatmentEye trackingNeural systemsAdaptive behaviorBrain regionsBaseline measuresStriking gainsStimuliChildrenPositive effectMechanisms of change in psychosocial interventions for autism spectrum disorders
Lerner MD, White SW, McPartland JC. Mechanisms of change in psychosocial interventions for autism spectrum disorders. Dialogues In Clinical Neuroscience 2012, 14: 307-318. PMID: 23226955, PMCID: PMC3513684, DOI: 10.31887/dcns.2012.14.3/mlerner.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSpectrum disorderPsychosocial interventionsIntervention researchSocial information processingSocial communication deficitsASD intervention researchPsychosocial intervention researchActive therapeutic ingredientsMechanisms of changeExecutive functioningIndividual differencesSocial motivationInternalizing comorbidityInformation processingSocial knowledgeEmpirical supportTherapeutic ingredientsTherapeutic relationshipBehavior modificationFuture directionsInterventionTreatment responseLittle workResearch