2013
Brain mechanisms for prepulse inhibition in adults with Tourette syndrome: Initial findings
Zebardast N, Crowley MJ, Bloch MH, Mayes LC, Vander Wyk BV, Leckman JF, Pelphrey KA, Swain JE. Brain mechanisms for prepulse inhibition in adults with Tourette syndrome: Initial findings. Psychiatry Research 2013, 214: 33-41. PMID: 23916249, PMCID: PMC3932431, DOI: 10.1016/j.pscychresns.2013.05.009.Peer-Reviewed Original ResearchConceptsTourette syndromeFunctional magnetic resonance imagingHealthy subjectsTic severityWhole-brain functional magnetic resonance imagingYale Global Tic Severity ScaleTactile startle responseCase-control study designTic Severity ScaleCortical-striatal circuitsBrain activityMagnetic resonance imagingMultiple brain regionsLeft middle frontal gyrusMiddle frontal gyrusDegree of PPIPulse-alone stimuliBlock-design fMRI paradigmTic symptomsNeuropathological dataHealthy controlsPrepulse inhibitionDevelopmental neuropsychiatric disordersSensorimotor gatingLeft caudate
2010
Oxytocin, cortisol, and triadic family interactions
Gordon I, Zagoory-Sharon O, Leckman JF, Feldman R. Oxytocin, cortisol, and triadic family interactions. Physiology & Behavior 2010, 101: 679-684. PMID: 20723553, DOI: 10.1016/j.physbeh.2010.08.008.Peer-Reviewed Original Research
2000
Sensory phenomena in obsessive-compulsive disorder and Tourette's disorder.
Miguel EC, do Rosário-Campos MC, Prado HS, do Valle R, Rauch SL, Coffey BJ, Baer L, Savage CR, O'Sullivan RL, Jenike MA, Leckman JF. Sensory phenomena in obsessive-compulsive disorder and Tourette's disorder. The Journal Of Clinical Psychiatry 2000, 61: 150-6; quiz 157. PMID: 10732667, DOI: 10.4088/jcp.v61n0213.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderTourette's disorderDisorder groupTic-related obsessive-compulsive disorderSensory phenomenaDisorder diagnosisMental sensationsDisorder spectrumAlone groupClinical indicesAdult outpatientsBody sensationPatientsBodily sensationsHeterogeneous disorderPatients' performanceDisordersPhenotypic featuresSensationSemistructured interviewsPresent studyRepetitive behaviorsRecent studiesGroupInner tension